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Simon Khagi, MDNeuro-Oncologist

New Patients/Referrals: (984) 215-3627
Returns/Follow-up Appointments: (984) 974-0000

Dr. Simon Khagi is a neurological oncologist who joined the faculty of the University of North Carolina at Chapel Hill School of Medicine in 2016 as an assistant professor. Dr. Khagi holds dual academic appointments in the departments of Medicine and Neurosurgery. As the director of the UNC Neuro-Oncology and Brain Metastases Programs, Dr. Khagi works in close collaboration with a wide range of supportive specialties to provide patients with a truly multidisciplinary approach to the treatment of central nervous system malignancies.

In addition to his extensive experience with chemotherapy and genomic-guided therapy, he is also certified in the application of alternating electric field therapy (i.e., Optune) for the treatment of glioblastoma. His research efforts center around improving treatments for patients with aggressive brain tumors (i.e., glioblastoma) and metastatic disease to the brain from lung cancer. Specifically, his research focuses on novel stem cell-based therapies, neuro-immunotherapeutics, design of early phase clinical trials, and enhanced imaging techniques for brain tumors.

Prior to joining UNC, Dr. Khagi completed a one-year training fellowship in neurological oncology at Duke University. In 2015, he completed a three-year combined fellowship in hematology and medical oncology at Tufts Medical Center/Tufts University School of Medicine. In 2012, he completed a three-year residency in internal medicine at Dartmouth-Hitchcock Medical Center/Dartmouth Medical School. Dr. Khagi is a 2009 graduate of the combined/accelerated BA/MD program at the University of Missouri-Kansas City School of Medicine.

Assistant Professor of Medicine and Neurosurgery
Director, UNC Neuro-Oncology Program
Director, UNC Brain Metastases Program

Brain tumors
Spinal cord tumors
Metastatic brain tumors
Alternating electric field therapy
Genome-guided therapy
Stem cell-based therapies
Enhanced imaging techniques
Early phase clinical trial design

Fellowship – Neurological Oncology, Duke University Hospital, 2015 – 2016
Fellowship – Hematology and Medical Oncology, Tufts Medical Center, 2012 – 2015
Residency – Internal Medicine, Dartmouth-Hitchcock Medical Center, 2010 – 2012
Internship – Internal Medicine, Dartmouth-Hitchcock Medical Center, 2009 – 2010
M.D. and B.A. – University of Missouri, Kansas City in an accelerated combined program, 2002 – 2009

Internal Medicine: certified
Medical Oncology: certified
Neuro-Oncology: certified
Hematology: eligible