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Matt Ewend, MD


New Patients/Referrals: (919) 445-2410
Returns/Follow-up Appointments:  (984) 974-0000

Dr. Matthew G. Ewend is President of UNC Physicians and former Chair of the Department of Neurosurgery. He joined the faculty in 1997 after completing medical school, neurosurgery residency, and a brain tumor fellowship at The Johns Hopkins School of Medicine and The Johns Hopkins Hospital. Dr. Ewend’s clinical interests lie in the fields of brain tumors (including brain metastases), trigeminal neuralgia, radiosurgery, Chiari malformation, hydrocephalus and pediatric neurosurgery.

In addition to these roles, Dr. Ewend is the Chief Quality and Value Officer for the University of North Carolina Health Care System. He is also the Group Leader for NeuroOncology in the UNC Lineberger Comprehensive Cancer Center. His research interests are in novel imaging of the brain, treatment of brain metastases, and outcomes for endoscopic neurosurgery.

When asked about his goals for a new patient visit, Dr. Ewend says, “My first goal is to build a strong relationship with my patient and his or her family. In addition to a thoughtful review of their case, patients can expect an understandable explanation of their condition, discussion of all the treatment options, and my opinion as to which option(s) might be best. At UNC, we work in teams to bring you the best care. If needed, I will help you to assemble this team. I pride myself on making the issues of neurosurgery easy to understand for my patients. After all, it isn’t really rocket science. I look forward to meeting you.”

Dr. Ewend has been named to the 2019 Best Doctors in America® list.

UNC News:

Expert profile

Patient Stories:

Linda Hewitt
Grayson Clamp


  • Van L. Weatherspoon, Jr. Eminent Distinguished Professor, Department of Neurosurgery
  • President, UNC Physicians
  • Chief Quality and Value Officer, University of North Carolina Health Care System

Brain tumors, pituitary tumors, endoscopic surgery, metastatic tumors, CyberKnife®, skull base surgery and hydrocephalus.

Fellowship – Neuro-Oncology; The Johns Hopkins Hospital, 1994-1996
Residency – Neurosurgery; The Johns Hopkins Hospital, 1991-1997
Internship – Surgery; The Johns Hopkins Hospital, 1990-1991
M.D. – Medicine; Johns Hopkins University School of Medicine, 1990
B.A. – Mathematics, Health Sciences; Kalamazoo College, 1986

Neurological Surgery – Board Certified, 2001 (Re-certified 2011)

For recent publications, please visit Dr. Matt Ewend’s PubMed listing.