Multidisciplinary, integrated care is at the core of our management of pituitary tumors. Through cooperation between the Departments of Neurosurgery, Otolaryngology/Head and Neck Surgery, Radiology, Radiation Therapy, and the Division of Endocrinology, patients are managed in a truly integrated and holistic fashion.

Quinsey in surgeryOn the surgical side, Matthew Ewend, MD, Chair of the Department of Neurosurgery, along with Brent A. Senior, MD, Chief of the Division of Rhinology, Allergy, and Endoscopic Skull Base Surgery, became the first team in North Carolina to perform Minimally Invasive Pituitary Surgery (MIPS) to treat pituitary tumors in 2000. In contrast to traditional open approaches such as using endoscopes for visualization, the nose is used as a corridor to approach the tumor so that no facial or oral incisions are made, dramatically reducing the overall morbidity of the procedure. Recovery is rapid and no packing is typically used. “Hydroscopy,” a technique developed and popularized by Drs. Ewend and Senior, is performed following tumor removal in order to assess for residual tumor.

Management of the function of the pituitary gland is essential in the care of patients with pituitary tumors. Endocrinologist Elizabeth Harris, MD and her team, focus on both the treatment of pituitary tumors that produce too much hormone (Cushing’s disease, acromegaly, prolactinoma) and on restoring normal pituitary function in patients who have lost function as a result of their tumors.

Drs. Ewend and Senior, along with colleagues Adam Zanation, MD, and Carlos Ebert, MD, in the Department of Otolaryngology, and Dr. Deanna Sasaki-Adams in the Department of Neurosurgery, have become recognized experts in this exciting area, lecturing nationally and internationally on the topic, and authoring publications in several books and journals. They have performed over 800 of these procedures, placing University of North Carolina at the forefront of minimally invasive approaches to skull base tumors.

Pituitary Tumor Physician Team:


Matthew G. Ewend, MD, FACS

Carolyn Quinsey, MD

Endocrinology & Metabolism

David Clemmons, MD

Elizabeth Harris, MD, FACS

Otolaryngology/Head and Neck Surgery

Brent A. Senior, MD, FACS, FARS

Adam M. Zanation, MD;

Charles S. Ebert, Jr., MD, MPH

Department of Radiation Therapy

Colette Shen, MD, PhD

Department of Radiology

J. Keith Smith, MD, PhD

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