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GYN | A Necessary Multi-Parametric Evaluation of Vulvodynia
STUDY BRIEF | To develop novel tools and classification algorithms to identify the relative contribution of multiple pain mechanisms in individual patients to enhance diagnosis of vulvodynia and choice of tailored, mechanistic-based treatments.
Located in Research / Ongoing
GYN | ACE Trial for Overactive Bladder
Study Brief | The purpose of the ACE trial is to assess cognitive function in women taking an anticholinergic medication (trospium) for the treatment of overactive bladder. This medication is FDA-approved and is not experimental. There are rare reports of changes in cognitive function when taking any anticholinergic medication for overactive bladder. The goal is to administer written cognitive function tests to measure your cognitive function before and after starting medication.
Located in Research / Ongoing
GYN | Peripheral and Central Mechanisms of Vulvar Vestibulitis Syndrome (VVS)
STUDY BRIEF | To explore the relative contribution of the mucosal and muscle pain sensitivity to clinical pain report among women with vestibulodynia.
Located in Research / Ongoing
GYN | The URGE Trial
Study Brief | The purpose of this research study is to determine genes that affect how a person’s body metabolizes a drug can help us predict how women will respond to a FDA approved medication (fesoterodine fumarate) for urgency urinary incontinence (UUI).
Located in Research / Ongoing
GYN | VAULT study for pelvic organ prolapse
STUDY BRIEF | The purpose of this research study is to learn about the effectiveness of 2 surgical techniques for treatment of uterovaginal prolapse: Laparoscopic/ robotic-assisted sacral hysteropexy and Vaginal Uphold Hysteropexy will be compared. Both procedures leave the uterus in place and use mesh to support the uterus and vagina. The cure rates, complications, and improvement of symptoms after these two procedures will be compared.
Located in Research / Ongoing
Mood, Mother and Infant Study
You are invited to help UNC researchers understand how breastfeeding builds bonds between mothers and babies.
Located in Research / Ongoing
OB | Time to Conceive
STUDY BRIEF | Time to Conceive is a research study that hopes to find a way to accurately measure a woman’s fertility. Women between 30 and 44 years of age who are trying to become pregnant or about to start trying are eligible to participate in the study. Women are not eligible to participate if they or their partner have a history of infertility or fertility treatment.
Located in Research / Ongoing