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Professor, Gynecologic Oncology

Daniel L. Clarke-Pearson, MD, Professor of Obstetrics and Gynecology, was born and raised in Southern California. He attended Harvard College, majoring in Biology. He was a two-year varsity football letterman and played in the epic 1968 “Harvard Beats Yale: 29-29 Game.” After working as a technician in a vascular laboratory at the West Roxbury Veterans Administration Hospital in West Roxbury, MA, he attended Case Western Reserve University School of Medicine in Cleveland, Ohio.

Dr. Clarke-Pearson completed a residency in Obstetrics and Gynecology (Roy T. Parker, MD, Chair) and a fellowship in Gynecologic Oncology (William T. Creasman, MD, Director) at Duke University, Durham, NC. He joined the Duke faculty as an Assistant Professor in the Division of Gynecologic Oncology in 1981. Between 1985-87 he was the director of Gynecology and Gynecologic Oncology at the University of Illinois in Chicago.(William Spellacy, MD, Chair) He returned to Duke University Medical Center in 1987 as a tenured Professor and Director of the Division of Gynecologic Oncology (Charles B. Hammond, MD, Chair). He was named the James Ingram Professor of Gynecologic Oncology in 1993. Throughout his Duke tenure, he was the director of the fellowship in Gynecologic Oncology. Sixteen of his eighteen fellows accepted academic positions in university medical centers.

In 2005 Dr. Clarke-Pearson accepted the role of Chair of the Department of Obstetrics and Gynecology at the University of North Carolina, Chapel Hill, a role he filled until stepping down to rejoin the gynecologic oncology faculty in July 2019.

In 2016 U.S. News & World Report ranked the UNC OB-GYN Department #11 in the U.S. and #1 in North Carolina. In the same year, the UNC OB-GYN Residency was ranked #3 in the US and #1 in the Southeast.

Dr. Clarke-Pearson’s primary research interest has been in the prevention, treatment and diagnosis of venous thromboembolic events (VTE) with particular interest in gynecologic surgery. He has conducted numerous randomized clinical trials evaluating prophylactic methods that have set the standard of current clinical care. His research interests also include the entire field of clinical gynecologic oncology. He has published more than 250 scientific papers in peer-reviewed journals, more than 50 textbook chapters and three textbooks.

Dr. Clarke-Pearson has been an active participant in committees of the Gynecologic Oncology Group and the American College of Obstetricians and Gynecologists and has led CME courses on complex gynecologic surgery at the ACOG Annual Clinical Meeting for over a decade. He served a 6year term (3 as Chair) of the ACOG Gyn Practice Committee and on the ACOG Executive Board. He has been a member of the ObGyn Advisory Committee of the American College of Surgeons. He served for 18 years as an examiner of the American Board of Obstetrics and Gynecology. He was the 2010-2011 President of the Society of Gynecologic Oncologists.
Currently, Dr. Clarke-Pearson is a member of the ACOG Grievance Committee and is the President of the Council of University Chairs of OB-GYN (CUCOG). He continues to have an active, full-scope practice of gynecologic oncology.

Clinical Profile

Daniel Lyle Clarke-Pearson, MD – UNC Health Care

Daniel Clarke-Pearson – UNC Lineberger Comprehensive Cancer Center

Areas of Research

  • ovarian cancer
  • uterine cancer
  • cervical cancer
  • chemotherapy
  • radical pelvic surgery
  • reconstructive surgery
  • treatment of cervix dysplasia
  • laser therapy
  • gynecological cancer
  • clinical trials
  • prevention of venous thrombosis
  • Address

    Division of Gynecologic Oncology

    CB 7570

    Chapel Hill, NC 27599-7570