UNC Program for Precision Medicine in Health Care (PPMH), which aims to transform patient care through evidence-based precision medicine, and the North Carolina Translational and Clinical Sciences (NC TraCS) Institute at The University of North Carolina at Chapel Hill (UNC-CH) have awarded four pilot grants for project that have direct clinical or human translational impact and are focused on the implementation of precision medicine approaches in the UNC Health system and the state of North Carolina. See full list.
Neeta Vora, MD, associate professor in the Division of Maternal-Fetal Medicine at UNC’s Department of Obstetrics and Gynecology, will lead the study, “Expanding the Utility of Non-Invasive Prenatal Genetic Testing.”
Non-invasive prenatal screening utilizing cell-free fetal DNA has the potential to identify large chromosomal abnormalities in the fetus. This proof-of-technology project will demonstrate an approach for the first sequencing-based screening panel to detect both dominant and recessive conditions in the fetus using maternal blood. The results from this study will build towards a new population-scale non-invasive prenatal test for medically actionable genetic diseases.