My research focuses on elucidating early pathogenesis in lung diseases, specifically cystic fibrosis, primary ciliary dyskinesia, and chronic lung disease of prematurity as well as the development of novel endpoints which identify and predict disease processes at earlier time points during preschool and infancy. I have also served as one of the PIs for three large therapeutic trials in young children with cystic fibrosis. I have extensive expertise in infant and preschool lung function testing and have led consensus groups in establishing guidelines for these measurements. My research group contributes to several multicenter investigations in the areas of cystic fibrosis and primary ciliary dyskinesia lung disease pathogenesis, endpoint validation, and interventional studies. I currently serve as contact PI for the Genetic Disorders of Mucociliary Clearance Consortium (2U54HL096458) which is a part of the NCATS-sponsored Rare Disease Clinical Research Network.<\/p>\n","protected":false},"featured_media":4295,"template":"","meta":{"_acf_changed":false},"affiliation":[55,54],"database-category":[295,297],"expert-year":[287],"class_list":["post-4293","faculty-expert","type-faculty-expert","status-publish","has-post-thumbnail","hentry","affiliation-childrens-research-institute","affiliation-peds","database-category-genetics-and-gene-therapy","database-category-respiratory-care-and-diseases","expert-year-287","odd"],"acf":[],"yoast_head":"\n