DPLM Faculty Profiles — Dr. Lawton
Thomas J. Lawton, MD
My main research interests are the study of high-risk breast lesions from a radiology/pathology perspective (with a particular focus on in situ lobular neoplasia) and other markers of breast cancer risk, including the study of specific molecular alterations related to breast cancer prediction, prognosis, and treatment.
Selected Journal Publications
O’Connor SM and Lawton TJ. Can Molecular Subtyping be Used to Guide Metastatic Screening in Breast Cancer? Am J Clin Pathol 2015; 143(4):468-70.
Lawton TJ, Acs G , Argani P, Farshid G, Gilcrease M, Goldstein N, Koerner F, Rowe JJ, Sanders M, Shah S, Reynolds C. Interobserver Variability by Pathologists in the Distinction Between Cellular Fibroadenomas and Phyllodes Tumors. Int J Surg Pathol 2014; 22(8):695-8.
Bartlett JM, Bloom KJ, Piper T, Lawton TJ, van de Velde CJ, Ross DT, Ring BZ, Seitz RS, Beck RA, Hasenburg A, Kieback D, Putter H, Markopoulos C, Dirix L, Seynaeve D, Rea D. Mammostrat as an Immunohistochemical Multigene Assay for Prediction of Early Relapse Risk in the Tamoxifen Versus Exemestane Adjuvant Multicenter Trial Pathology Study. J Clin Oncol. 30(36):4477-4484, 2012.
Georgian-Smith D and Lawton TJ. Variations in Physician Recommendations for Surgery After Diagnosis of a High-Risk Lesion on Breast Core Needle Biopsy. AJR Am J Roentgenol. 198(2):256-263, 2012.
Joh JE, Esposito NN, Kiluk JV, Laronga C, Lee MC, Loftus L, Soliman H, Boughey JC, Reynolds C, Lawton TJ, Acs PI, Gordon L, Acs G. The Effect of Oncotype DX Recurrence Score on Treatment Recommendations for Patients with Estrogen Receptor Positive Early Stage Breast Cancer and Correlation with Estimation of Recurrence Risk by Breast Cancer Specialists. Oncologist. 16(11): 1520-1526, 2011.
Linden HM, Kurland BF, Peterson LM, Schubert EK, Gralow JR, Specht JM, Ellis GK, Lawton TJ, Livingston RB, Petra PH, Link JM, Krohn KA, Mankoff DA. Fluoroestradiol Positron Emission Tomography Reveals Differences In Pharmacodynamics of Aromatase Inhibitors, Tamoxifen, and Fluvestrant in Patients with Metastatic Breast Cancer. Clin Cancer Res. 17(14):4799-4805, 2011.
Selected Books and Book Chapters
Georgian-Smith D and Lawton TJ. Breast Imaging and Pathologic Correlations: A Pattern-Based Approach. Philadelphia: Lippincott Williams and Wilkins, 2014.
Lawton TJ. High Risk Breast Lesions and Pathologic Evaluation. In: Hansen, NM, ed. Management of the Patient at High Risk for Breast Cancer. New York: Springer: pp. 61-67, 2013.
Calhoun KE, Lawton TJ, Kim JN, Lehman CD, Anderson BO. Phyllodes Tumors. In: Harris JR, Lippman ME, Morrow M, Osborne CK, eds. Diseases of the Breast (4th Edition). Philadelphia: Lippincott Williams & Wilkins: pp. 781-792, 2010.
Georgian-Smith D and Lawton TJ. Controversies on the Management of High Risk Lesions on Core Biopsy from a Radiology/Pathology Perspective. In: Radiologic Clinics of NA (volume 48:5): pp. 999-1012, 2010.
Lawton TJ. Breast (Cambridge Illustrated Surgical Pathology). New York: Cambridge University Press, 2009.
Future Presentations and Educational Courses
Lawton TJ. “In Situ Lobular Neoplasia: Current Concepts and Controversies.” 1st International Invasive Lobular Cancer Symposium. Pittsburgh, PA; September 29-30, 2016.
Ashley BE, Jordan SG, Lawton TJ. “ Lobular Neoplasia of the Breast: A Stronger Statement of an Old Issue. Poster Discussion Session: RSNA 102nd Annual Meeting. Chicago, IL: November 29, 2016.
Jordan SG, Mukherjee N, Bookhout C, Jordan ZS, Lawton TJ. Unwise Conventional Wisdom: Real Truths About Atypical and Malignant Solitary Papillary Lesions of the Breast. Platform Session: RSNA 102nd Annual Meeting. Chicago, IL: November 30, 2016.
Lawton TJ. “Breast Cancer Pathology: Markers and Gene Profiles.” SBI/ACR Breast Imaging Symposium. Los Angeles, CA; April 6-9, 2017.