{"id":2295,"date":"2009-12-29T18:45:00","date_gmt":"2009-12-29T23:45:00","guid":{"rendered":"https:\/\/med.sites.unc.edu\/pathology\/mcp\/pbts\/alumni\/"},"modified":"2024-09-26T09:50:54","modified_gmt":"2024-09-26T13:50:54","slug":"alumni","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pathology\/mcp\/mcp\/pbts\/for-prospective-students\/alumni\/","title":{"rendered":"Program Alumni"},"content":{"rendered":"<div style=\"text-align: center\">\n<p><img loading=\"lazy\" decoding=\"async\" style=\"border: 1px solid #666666\" title=\"splash-jennifer-lab\" src=\"https:\/\/www.med.unc.edu\/pathology\/mcp\/wp-content\/uploads\/sites\/639\/2018\/04\/splash-jennifer-lab.jpg\" alt=\"splash-jennifer-lab\" width=\"137\" height=\"100\" align=\"middle\" \/> <img loading=\"lazy\" decoding=\"async\" style=\"border: 1px solid #666666\" title=\"splash-josh-astern\" src=\"https:\/\/www.med.unc.edu\/pathology\/mcp\/wp-content\/uploads\/sites\/639\/2018\/04\/splash-josh-astern.jpg\" alt=\"splash-josh-astern\" width=\"131\" height=\"100\" align=\"middle\" \/> <img loading=\"lazy\" decoding=\"async\" style=\"border: 1px solid #666666\" title=\"splash-lea-2\" src=\"https:\/\/www.med.unc.edu\/pathology\/mcp\/wp-content\/uploads\/sites\/639\/2018\/04\/splash-lea-2.jpg\" alt=\"splash-lea-2\" width=\"133\" height=\"100\" align=\"middle\" \/><\/p>\n<div style=\"text-align: left\">\n<h2 style=\"text-align: center\">Graduates of the Pathobiology and Translational Science Graduate Program<\/h2>\n<h2 style=\"text-align: center\">2023<\/h2>\n<p><strong>Mattew Combs, Ph.D.<br \/>\n<\/strong>Dissertation title: The Role of GRAF RhoA-GAPs in Maintaining Highly Energetic Tissues via Regulation of Mitochondrial Quality Control<br \/>\nAdvisor: Joan Taylor<\/p>\n<p><strong>Cherise Glodowski, Ph.D.<\/strong><br \/>\nDissertation title: Identification of Intra-tumoral Heterogeneity, Drug-Induced Cellular Subpopulation Shifts, and novel metabolic Profiles in Triple Negative Breat Cancer Models<br \/>\nAdvisor: Charles Perou<\/p>\n<p><strong>Drevon Dobson, Ph.D.<\/strong><br \/>\nThe Genetic Regulation of Fibrinogen Synthesis<br \/>\nAdvisor: Alisa Wolberg<\/p>\n<p><strong>Emma Bouck, Ph.D.<\/strong><br \/>\nMechanisms of Hormone-Associated Venous Thromboembolism<br \/>\nAdvisor: Alisa Wolberg<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<div style=\"text-align: left\">\n<h2 style=\"text-align: center\">2022<\/h2>\n<p>&nbsp;<\/p>\n<p><strong>Christian Agosto-Burgos, Ph.D.<br \/>\n<\/strong>Dissertation title: Profiling the Heterogeneity of T Regulatory Cells in Patients with Anti-Neutrophil Cytoplasmic Autoantibodies (ANCA) Vasculitis<br \/>\nAdvisor: Ronald Falk<\/p>\n<p><strong>Bethany Brown, Ph.D.<br \/>\n<\/strong>Dissertation title: Novel Mouse Models for Investigating Genetic Drivers and Influencers of Oral Squamous Cell Carcinomas<br \/>\nAdvisor: Scott Williams<\/p>\n<p><strong>Johnny Castillo Cabrera, Ph.D.<br \/>\n<\/strong>Dissertation title: AGC Kinase Inhibitors Regulate STING Signaling by SGK-dependent and SGK-independent Mechanisms<br \/>\nAdvisor: Albert Baldwin<\/p>\n<p><strong>Taylor Dismuke, Ph.D.<br \/>\n<\/strong>Dissertation title:\u00a0Advancing Targeted Therapy for SHH Medulloblastoma by Addressing Resistance Mechanisms<br \/>\nAdvisor: Timothy Gershon<\/p>\n<p><strong>Alina Hamilton, Ph.D.<br \/>\n<\/strong>Dissertation title: The Landscape of Immune Microenvironments in Racially Diverse Breast Cancer Patients<br \/>\nAdvisor: Melissa Troester and Katie Hoadley<\/p>\n<p><strong>Carolina Herrera, Ph.D.<br \/>\n<\/strong>Dissertation title: Monocytes in Autoimmune Kidney Disease: Their Role as Biomarkers and Drivers of Anca Vasculitis and Systemic Lupus Erythematosus<br \/>\nAdvisor: Ronald Falk<\/p>\n<p><strong>Benjamin Keepers, Ph.D.<br \/>\n<\/strong>Dissertation title: A Change of Heart: Novel Approaches to Direct Cardiac Reprogramming<br \/>\nAdvisor: Li Qian<\/p>\n<p><strong>Dominique Munson, Ph.D.<\/strong><br \/>\nDissertation title: Evaluating Low- And Normal-Density Neutrophils Profile And Pathological Mechanisms In ANCA Vasculitis<br \/>\nAdvisor: Ronald Falk<\/p>\n<p><strong>Jean Marie Mwiza, Ph.D.<br \/>\n<\/strong>Dissertation title: Determining the Platelet Signaling Pathway(s) Critical in Venous Thrombosis Pathogenesis<br \/>\nAdvisor: Wolfgang Bergmeir and Alisa Wolberg<\/p>\n<p><strong>Abigail Shelton, Ph.D.<br \/>\n<\/strong>Dissertation title: Transcriptomic and Proteomic Responses to Targeted Inhibitors in Glioblastoma: In Pursuit of Personalized Combination Therapies<br \/>\nAdvisor: C. Ryan Miller<\/p>\n<p><strong>Markia Smith, Ph.D.<\/strong><br \/>\nDissertation title: Developing Methods to Detect DNA Repair Defects in a Diverse Population<br \/>\nAdvisor: Melissa Troester and Katie Hoadley<\/p>\n<p><strong>Erin Smithberger, Ph.D.<br \/>\n<\/strong>Dissertation title: Kinome-guided Development of Precision-Targeted Therapeutics for Glioblastoma<br \/>\nAdvisor: C. Ryan Miller<\/p>\n<h2 style=\"text-align: center\">2020<\/h2>\n<p><strong>Haley Chi, Ph.D.<br \/>\n<\/strong>Dissertation title: Molecular Mechanisms of Direct Cardiac Reprogramming<br \/>\nAdvisor: Li Qian<\/p>\n<p><strong>Michael Henderson, Ph.D.<br \/>\n<\/strong>Dissertation title: Coagulation -Independent Role of High Molecular Weight Kininogenin Acute Liver Failure<br \/>\nAdvisor: Nigel Key<\/p>\n<p><strong>Krystal Orlando, Ph.D.<\/strong><br \/>\nDissertation title: The Epigenetic Consequences of BRG1 Loss in Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) Tumorigenesis<br \/>\nAdvisor: Bernard Weissman<\/p>\n<h2 style=\"text-align: center\">2019<\/h2>\n<p><strong>Sabri Abdelwahab, Ph.D.<br \/>\n<\/strong>Dissertation title: Characterizing the Effect of New and Emerging Tobacco Products on the Airway Innate Mucosal Defense<br \/>\nAdvisor: Mehmet Kesimer<\/p>\n<p><strong>Bethany Batson, Ph.D.<\/strong><br \/>\nDissertation title: Airway Mucin Dynamics in Infection and Inflammation<br \/>\nAdvisor: Mehmet Kesimer<\/p>\n<p><strong>Rachel Dee, Ph.D.<\/strong><br \/>\nDissertation title: Characterizing the Molecular Mechanisms of Blood Pressure Regulation by GRAF3, a Smooth Muscle-Specific RhoGAP<br \/>\nAdvisor: Joan Taylor<\/p>\n<p><strong>Nicole Fleming, Ph.D.<\/strong><br \/>\nDissertation title: Molecular Regulation of Cardiovascular Development and Disease<br \/>\nAdvisor: Jiandong Liu<\/p>\n<h2 style=\"text-align: center\">2018<\/h2>\n<p><strong>James Byrnes, Ph.D.<\/strong><br \/>\nDissertation title: Defining the Interactions Between Coagulation Factor XIII, Fibrin(ogen), and Red Blood Cells<br \/>\nAdvisor: Alisa Wolberg<\/p>\n<p><strong>Ashley Fuller, Ph.D.<\/strong><br \/>\nDissertation title: Triple-Negative Breast Cancer Microenvironments: Molecular and Histologic Portraits<br \/>\nAdvisor: Melissa Troester<\/p>\n<p><strong>Katherine Stember, Ph.D.<br \/>\n<\/strong>Dissertation title: Identifying Pathogenic Epitopes and Autoreactive Cells in ANCA Vasculitis<br \/>\nAdvisor: Ronald J. Falk<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">2017<\/h2>\n<p><b>Pamela Lockyer,<\/b><b> M.S.<\/b><br \/>\nDissertation title: <span style=\"color: #000000\">Bone Morphogenetic Protein Precursor Regulator (BMPER) Regulates Vascular Inflammatory Responses in Endothelial Cells<\/span><br \/>\nAdvisor: Xinchun Pi<\/p>\n<p><b>Kevin Mangum,<\/b><b> Ph.D.<\/b><br \/>\nDissertation title: Identification of Critical RhoA Signaling Components in Vascular Development and Hypertension<br \/>\nAdvisor: Christopher Mack<\/p>\n<p><b>Robbie McNeill,<\/b><b> Ph.D.<\/b><br \/>\nDissertation title: Defining the Role of PI3K Pathway Mutations in Gliomagenesis and Drug Response<br \/>\nAdvisor: Ryan Miller<\/p>\n<h2 style=\"text-align: center\">2016<\/h2>\n<p><b><b>Britta Jones,<\/b><b> Ph.D.<\/b><br \/>\n<\/b>Dissertation title: DNA Methylation Patterns as a Biomarker of Disease Relapse and Remission in Patients with ANCA-associated Vasculitis<br \/>\nAdvisor: Ronald J. Falk<\/p>\n<p><b>Amanda Rinkenbaugh,<\/b><b> Ph.D.<\/b><br \/>\nDissertation title: Roles of the NF-kappaB Pathway in Glioblastoma Stem Cells and Chordoma<br \/>\nAdvisor: Albert Baldwin<\/p>\n<h2 style=\"text-align: center\">2015<\/h2>\n<p><b>Julia Geddings, M.D.<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: The Role of Tumor Microparticles in Cancer-associated Thrombosis<br \/>\nAdvisor: Nigel Mackman<\/p>\n<p><b>Justine Monk<\/b><b>, M.S.<\/b><br \/>\nThesis title: Inflammatory Responses Induced By Cigarette Smoke, In Healthy Mice and In Mice with Chronic Bronchitis<br \/>\nAdvisor: Claire Doerschuk<\/p>\n<p><b>Adam Pfefferle, Ph.D.<\/b><br \/>\nDissetation title: Genetically Engineered Mouse Models of Breast Carcinoma: A Translational Resource for Highlighting Human Breast Subtype Etiology and Developing Personalized Therapeutic Approaches<br \/>\nAdvisor: Charles Perou<\/p>\n<p><b>Bethany Walton<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: The Contribution of Fibrinogen and Red Blood Cells to Arterial Thrombosis<br \/>\nAdvisor: Alisa Wolberg<\/p>\n<p><b>Laura Weiss-Cross<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: Regulation of Smooth Muscle Cell Phenotype by the RhoA Effectors mDia1 and mDia2<br \/>\nAdvisor: Christopher Mack<\/p>\n<h2 style=\"text-align: center\"><\/h2>\n<h2 style=\"text-align: center\">2014<\/h2>\n<p><b>Maria Aleman<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: Cellular and Plasma Protein Crosstalk in Arterial and Venous Thrombosis<br \/>\nAdvisor: Alisa Wolberg<\/p>\n<p><b>Dinuka De Silva<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: Role of Androgen Receptor Co-repressor SLIRP in Cell Cycle Regulation<br \/>\nAdvisor: Young Whang<\/p>\n<p><b>Kaitlin Lenhart<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: The Rho-GAP GRAF1 Regulates Skeletal Muscle Maturation and Repair<br \/>\nAdvisor: Joan Taylor<\/p>\n<p><b>Lantz Mackey<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: The Role of \u0251(1,3)-Fucosylated Glycans in Homeostatic Immunity, Granulopoiesis, and Mucosal Injury<br \/>\nAdvisor: Jonathon Homeister<\/p>\n<p><b>Kristine Wadosky<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: Cardiac Muscle RING Finger 1 inhibits adaptive hypertrophic remodeling induced by IGF-1, Exercise, and Thyroid Hormone<br \/>\nAdvisor: Monte Willis<\/p>\n<h2 style=\"text-align: center\">2013<\/h2>\n<p><b>Patricia Casbas Hernandez<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: In vitro Coculture Models to Study Heterotypic Interactions in Breast Cancer Microenvironments<br \/>\nAdvisor: Melissa Troester<\/p>\n<p><b>Michael Durando<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: Novel DNA Damage Tolerance Mechanisms Mediated by Translesion Synthesis<br \/>\nAdvisor: Cyrus Vaziri<\/p>\n<p><b>Meghan Free<\/b><b>, Ph.D.<\/b><br \/>\nDissertation title: Role of Circulating T Cells in Autoimmune Kidney Disease: Implications for ANCA Disease and Minimal Change Disease<br \/>\nAdvisor: Ronald J. Falk<\/p>\n<\/div>\n<div style=\"text-align: left\">\n<h2 style=\"text-align: center\">2012<\/h2>\n<p><b>Jessica C. Cardenas, Ph.D.<\/b><br \/>\nDissertation title: The Role of p16INK4a Expression in the Age-related Risk of Venous Thromboembolism<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>David A. Detwiler, Ph.D.<\/b><br \/>\nDissertation title: Isolation and Characterization of Primary Canine Satellite Cells in the GRMD Model<br \/>\nAdvisor: Joe Kornegay<\/p>\n<p><b>Aleeza J. Roth, Ph.D.<\/b><br \/>\nDissertation title: Characterization of Antigenic Determinants and Their Correlation with Disease Activity in ANCA Glomerulonephritis<br \/>\nAdvisor: Ronald J. Falk<\/p>\n<h2 style=\"text-align: center\"><\/h2>\n<h2 style=\"text-align: center\">2011<\/h2>\n<p><b>Rachel Beaulieu Goldsmith, Ph.D.<\/b><br \/>\nDissertation title: Detection and Mechanistic Comparison of Two Anti-Trypanosomal Diamidines in a Rat Renal Model<br \/>\nAdvisor: Richard T. Tidwell<\/p>\n<p><b>Lance A. Johnson, Ph.D.<\/b><br \/>\nDissertation title: Apolipoprotein E in Diabetic Dyslipidemia and Atherosclerosis<br \/>\nAdvisor: Nobuyo N. Maeda<b> <\/b><\/p>\n<p><b>\u00a0<\/b><\/p>\n<p><b>Kellie Rae Machlus, Ph.D.<\/b><br \/>\nDissertation title: Pathophysiology of Plasma Hypercoagulability in Thrombosis<br \/>\nAdvisor: Alisa S. Wolberg<\/p>\n<p><b><br \/>\nTroy A. McEachron, Ph.D.<\/b><br \/>\nDissertation title: Regulation of Urokinase Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Murine Breast Cancer Cells<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Jessica E. Rodriguez, Ph.D.<\/b><br \/>\nDissertation title: Muscle Ring Finger-1 (MuRF1) Inhibits PPAR\u03b1 Activity to Modulate Cardiac Metabolism<br \/>\nAdvisor: Monte S. Willis<\/p>\n<p><b>Lisa L. Samuelson, M.S.<\/b><br \/>\nThesis title: Sca-1 Positive Pancreatic Progenitor Cells: A Replacement for Transplanted Islets<br \/>\nAdvisor: David A. Gerber<\/p>\n<p><b>Rupninder Sandhu, Ph.D.<\/b><br \/>\nDissertation title: Hypermethylator Phenotype in Human Breast Cancer: Therapeutic Target and Mechanism of DNMT3b Dysregulation<br \/>\nAdvisor: William B. Coleman<\/p>\n<h2 style=\"text-align: center\">2010<\/h2>\n<div style=\"text-align: left\">\n<p>&nbsp;<\/p>\n<p><b>Jason Thomas Doherty, Ph.D.<\/b><br \/>\nDissertation title: Focal Adhesion Kinase and ARHGAP26 in Cardiac and Skeletal Muscle Development<br \/>\nAdvisor: Joan M. Taylor<\/p>\n<p><b> <\/b><b>Mark W. Gramling, Ph.D.<\/b><br \/>\nDissertation title: Serine Proteases and Serine Protease Inhibitors in Breast Cancer Cell Pathophysiology<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Mehmet Karaca, Ph.D.<\/b><br \/>\nDissertation title: Androgen Receptor Activation by Ack1<br \/>\nAdvisor: Young E. Whang<\/p>\n<p><b>Matthew Douglas Medlin, Ph.D.<\/b><br \/>\nDissertation Title: Sphingosine-1-Phosphate and the RGS RhoGEFs Regulate Vascular Smooth Muscle Phenotype<br \/>\nAdvisor: Christopher P. Mack<\/p>\n<\/div>\n<p><b>Elizabeth Parker Merricks, Ph.D.<\/b><br \/>\nDissertation title: Cardiovascular Disease, Endothelial Cell Gene Expression, and Renal Dysfunction in Insulin Resistant, Hyperlipidemic Swine<br \/>\nAdvisor: Timothy C. Nichols<\/p>\n<p><b>Avani A. Pendse, Ph.D.<\/b><\/p>\n<p>Dissertation title: Peroxisome Proliferator Activated Receptor-gamma P465L Point Mutation in Diabetes and Atherosclerosis<br \/>\nAdvisor: Nobuyo Maeda<\/p>\n<p><b>Chih-Hong Wang, Ph.D.<\/b><br \/>\nDissertation title: Inhibition of Renin Angiotensin System Improves Leptin and Insulin Sensitivity, but Impairs Erythropoiesis in Bone Marrow via Thyroid Hormone<br \/>\nAdvisor: Nobuyuki Takahashi<\/p>\n<h2 style=\"text-align: center\">2009<\/h2>\n<p style=\"text-align: left\"><b>Diane E. Bender, Ph.D.<\/b><br \/>\nDissertation title: Characterization of a Feline Model of Factor XII Deficiency: The In Vivo Role of FXII in Vascular Injury and Inflammatory Responses<br \/>\nAdvisor: Dwight A. Bellinger<\/p>\n<p><b>Robert A. Campbell, Ph.D.<\/b><br \/>\nDissertation title: The Role of Different Vascular Cells in Fibrin Clot Formation and Structure<br \/>\nAdvisor: Alisa S. Wolberg<\/p>\n<p><b>Jennifer C. Carter, Ph.D.<\/b><br \/>\nDissertation title: PPAR-gamma Ligands and Adipocytes Regulate Expression of the Plasminogen Activator System in Breast Cancer<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Kathleen R. Nevis, Ph.D.<\/b><br \/>\nDissertation title: Molecular Characterization of a Replication Licensing Checkpoint<br \/>\nAdvisor: Marila Cordeiro-Stone and Jeanette G. Cook<\/p>\n<p><b>Christopher M. Scull, Ph.D.<\/b><br \/>\nDissertation title: The Role of Platelet-Macrophage Interactions in Inflammation and Wound Healing<br \/>\nAdvisor: Thomas H. Fischer<\/p>\n<p><b>Dean P. Staus, Ph.D.<\/b><br \/>\nDissertation title: Regulation of Smooth Muscle Specific Gene Transcription by the Diaphanous-Related Formins<br \/>\nAdvisor: Christopher P. Mack<\/p>\n<p><b>Xuebin Yang, Ph.D.<\/b><br \/>\nDissertation title: Molecular and Cellular Mediators in Radiation-Induced Lung Injury<br \/>\nAdvisor: Suzanne L. Kirby<\/p>\n<h2 style=\"text-align: center\">2008<\/h2>\n<p style=\"text-align: left\"><b>Jeremiah S. Hinson, Ph.D.<\/b><br \/>\nThe Regulation of Myocardin Factor-Dependent Transcription in Vascular Smooth Muscle<br \/>\nAdvisor: Christopher P. Mack<\/p>\n<p><b>Lee E. Mangiante, M.S.<\/b><br \/>\nThesis title: The Role of Focal Adhesion Kinase in Vascular Smooth Muscle Cell Migration<br \/>\nAdvisor: Joan M. Taylor<\/p>\n<p><b>Hind E. Muallem, Ph.D.<\/b><br \/>\nDissertation title: Association of Genetic Variations in the 3\u2019UTR of the Human Low Density Lipoprotein Receptor with the Lipid Parameters in the Atherosclerosis Risk in Communities (ARIC) Study<br \/>\nAdvisor: Nobuyo Maeda<\/p>\n<p><b>Liliana A. Ponguta, Ph.D.<\/b><br \/>\nDissertation title: Androgen Receptor and Epidermal Growth Factor Signaling in Prostate Cancer<br \/>\nAdvisor: Elizabeth M. Wilson<\/p>\n<p><b>Jill C. Rau, Ph.D.<\/b><br \/>\nDissertation title: Engineering of Serpins for Vascular Application<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Jacqueline Risher Roll, Ph.D.<\/b><br \/>\nDissertation title: Mechanism and Consequence of the Hypermethylator Phenotype in Human Breast Cancer<br \/>\nAdvisor: William B. Coleman<\/p>\n<p><b>Kristen King White, M.S.<\/b><br \/>\nThesis title: Investigation of a Novel +ACA BRCA1 Promoter Polymorphism and Its Impact on the Breast Cancer Susceptibility Phenotype<br \/>\nAdvisor: William B. Coleman<\/p>\n<h2 style=\"text-align: center\">2007<\/h2>\n<div style=\"text-align: left\">\n<p><b>Michael Altenburg, Ph.D.<\/b><br \/>\nDissertation title: Atherosclerotic Mechanisms of Apolipoprotein E Isoforms<br \/>\nAdvisor: Nobuyo Maeda<b> <\/b><\/p>\n<p><b>Joshua M. Astern, Ph.D. <\/b><br \/>\nDissertation title: Myeloperoxidase in Vascular Disease and Autoimmunity<br \/>\nAdvisor: Ronald J. Falk<\/p>\n<p><b>Lea M. Beaulieu, Ph.D. <\/b><br \/>\nDissertation title: Role of the Protein C System in Breast Cancer Cell Invasion and Endothelial Cell Angiogenesis<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>D. Hunter Best, Ph.D. <\/b><br \/>\nDissertation title: Liver Regeneration by Small Hepatocyte-like Progenitor Cells After Hepatotoxic and Necrotic Injury in Fischer 344 Rats<br \/>\nAdvisor: William B. Coleman<\/p>\n<p><b>Jessica N. DelBove, Ph.D. <\/b><br \/>\nDissertation title: Characterization of the Tumor Suppressor Capabilities of SWI\/SNF Complex Member BAF155 in Cancer Cell Lines and Cooperation of SNF5 and p53 Pathways<br \/>\nAdvisor: Bernard E. Weissman<\/p>\n<p><b>Laura A. DiMichele, Ph.D. <\/b><br \/>\nDissertation title: Focal Adhesion Kinase in Cardiac Development and Disease<br \/>\nAdvisor: Joan M. Taylor<\/p>\n<p><b>Jennifer Bushman Gilner, Ph.D. <\/b><br \/>\nDissertation title: Enrichment of Therapeutic Hematopoietic Stem Cell Populations From Embryonic Stem Cells<br \/>\nAdvisor: Suzanne Kirby<\/p>\n<p><b>Jennifer E. Jahn, Ph.D. <\/b><br \/>\nDissertation title: Identification of Synaptotagmin XIII as a Liver Tumor Suppressor Gene<br \/>\nAdvisor: William B. Coleman<\/p>\n<p><b>Terrence D. Lewis, Ph.D. <\/b><br \/>\nDissertation title: Mechanisms of Estrogen Sensitivity in the Human Endometrium<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Liisa Sundberg Smith, Ph.D. <\/b><br \/>\nDissertation title: A Role for Focal Adhesion Kinase in Vascular Smooth Muscle Cell Proliferation, Migration, and Differentiation<br \/>\nAdvisor: Joan M. Taylor<\/p>\n<\/div>\n<h2 style=\"text-align: center\">2005<\/h2>\n<p>&nbsp;<\/p>\n<div style=\"text-align: left\">\n<p><b>Jingjing Chai, Ph.D.<\/b><br \/>\nDissertation title: Identification of the Signal Transduction Pathway and Functional Domains of hSNF5 in Human Rhabdoid Tumor Cell Line and Mouse Rhabdoid Tumors<br \/>\nAdvisor: Bernard E. Weissman<\/p>\n<p><b>Danny R. Gray, Ph.D. <\/b><br \/>\nDissertation title: Effects of Androgen Deprivation on the Human Prostate Microenvironment<br \/>\nAdvisor: Gary J. Smith<\/p>\n<p><b>Timothy P. Heffernan, Ph.D. <\/b><br \/>\nDissertation title: Mechanisms of S Checkpoint Function in Human Cells<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<p><b>Charlotte A. Lanteri, Ph.D. <\/b><br \/>\nDissertation title: Mechanisms of Uptake and Action of DB75 [2,5-bis(4-amidinophenyl)furan] in African Trypanosomes<br \/>\nAdvisor: Richard R. Tidwell<\/p>\n<p><b>Julie L. Ryan, Ph.D. <\/b><br \/>\nDissertation title: Prevalence of Epstein-Barr Virus in Gastric Mucosa and Influences on Selected Gene Expression in Gastric Carcinoma<br \/>\nAdvisor: Margaret L. Gulley<\/p>\n<p><b>Lisa Marie Sturk, Ph.D. <\/b><br \/>\nDissertation title: Comparative Pharmacokinetics of DB289 and DB844: Investigating Improved Prodrug Efficacy Against Mouse Models of Sleeping Sickness<br \/>\nAdvisor: Richard R. Tidwell<\/p>\n<p><b>Yau-Sheng Tsai, Ph.D. <\/b><br \/>\nDissertation title: Peroxisome Proliferator-Activated Receptor Gamma in the Metabolic Syndrome<br \/>\nAdvisor: Nobuyo Maeda<\/p>\n<\/div>\n<h2 style=\"text-align: center\">2004<\/h2>\n<p style=\"text-align: left\"><b>Brandi Whitley Hilder, Ph.D. <\/b><br \/>\nDissertation title: Plasminogen Activator Inhibitor-1 in Breast and Ovarian Cancer Invasion<br \/>\nAdvisor: Frank C. Church<\/p>\n<h2 style=\"text-align: center\">2003<\/h2>\n<div style=\"text-align: left\">\n<p><b>Susan D. Hester, Ph.D. <\/b><br \/>\nDissertation title: Genetic Events Involved in Formaldehyde-induced Carcinogenesis<br \/>\nAdvisor: Douglas C. Wolf<\/p>\n<p><b>William F. Pendergraft III, Ph.D. <\/b><br \/>\nDissertation title: In Depth Analysis of the Myeloid Protease, Proteinase 3, as an Autoantigen and a Mediator of Vascular Injury<br \/>\nAdvisor: Ronald J. Falk<\/p>\n<\/div>\n<h2 style=\"text-align: center\">2002<\/h2>\n<div style=\"text-align: left\">\n<p><b>Bryan L. Betz, Ph.D. <\/b><br \/>\nDissertation title: The hSNF5\/INI1 Tumor Suppressor Gene: Mutational Analysis and Functional Characterization<br \/>\nAdvisor: Bernard E. Weissman<\/p>\n<p><b>Sharon Ricketts Betz, Ph.D.<\/b><br \/>\nDissertation title: Identification and Characterization of Candidate Liver Tumor Suppressor Genes from Human Chromosome 11p11.2-p12<br \/>\nAdvisor: William B. Coleman<\/p>\n<p><b>Paula B.Deming, Ph.D. <\/b><br \/>\nDissertation title: Mechanisms of Human Decatenation Checkpoint Function<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<p><b>Jeffrey B. Hodgin, Ph.D., M.D. <\/b><br \/>\nDissertation title: Molecular Mechanisms of Atheroprotection by 17b-estradiol<br \/>\nAdvisor: Nobuyo N. Maeda<\/p>\n<p><b>Nazumi Alice S. Yamada, Ph.D. <\/b><br \/>\nDissertation title: Microsatellite Instability in the Absence of Mismatch Repair Defects<br \/>\nAdvisor: Rosann A. Farber<\/p>\n<p><b>Suzanne T. Newberry, M.S. <\/b><br \/>\nThesis title: Methylation-dependent Epigenetic Silencing of BRCA1 in Sporadic Breast Cancer<br \/>\nAdvisor: William B. Coleman<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">2001<\/h2>\n<div style=\"text-align: left\">\n<p><b>Kelly A. Hogan, Ph.D. <\/b><br \/>\nDissertation title: Fibrinogen Vlissingen\/Frankfurt IV: Studies with Recombinant Fibrinogen and Gene-Targeted Mice<br \/>\nAdvisor: Susan T. Lord<\/p>\n<p><b><br \/>\nJennifer Wemhoff Mitchell, Ph.D. <\/b><br \/>\nDissertation title: Structure, Function, and Physiological Role of Heparin Cofactor II<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Dorothy H. Wood, Ph.D. <\/b><br \/>\nDissertation title: The Role of Imidazoline Receptors in 1,5-Bis(4-Amidinophenoxy) Pentane (Pentamidine) Toxicity<br \/>\nAdvisor: Richard R. Tidwell<\/p>\n<p><b>Alexis T. Henry, M.S. <\/b><br \/>\nThesis title: Characterization of Single Nucleotide Polymorphisms (SNPs) in Protein C Inhibitor<br \/>\nAdvisor: Frank C. Church<\/p>\n<\/div>\n<h2 style=\"text-align: center\">2000<\/h2>\n<div style=\"text-align: left\">\n<p><b>Mohammed BaSalamah, Ph.D. <\/b><br \/>\nDissertation title: Testican: Novel Human Gene Product<br \/>\nAdvisor: Cora-Jean S. Edgell<\/p>\n<p><b>Cheryl A. Cistulli, Ph.D. <\/b><br \/>\nDissertation title: Cell Cycle Checkpoints and Human Carcinogenesis<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<p><b>Gavin J. Gordon, Ph.D.<\/b><br \/>\nDissertation title: Characterization of the Cellular Responses During Liver Regeneration in Retrorsine-exposed Rats and Identification of a Novel Hepatic Progenitor Cell<br \/>\nAdvisor: William B. Coleman<\/p>\n<p><b>Tara N. Lyons-Darden, Ph.D.<\/b><br \/>\nDissertation title: The Role of DNA Instability in Triplet Repeat Expansion During in vitro DNA Replication<br \/>\nAdvisor: Michael D. Topal<\/p>\n<p><b>Diane Palmieri, Ph.D. <\/b><br \/>\nDissertation title: Serpins in Cancer<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Arti C. Patel, Ph.D. <\/b><br \/>\nDissertation title: Analysis of Candidate Suseceptability Genes and the Role of DNA Methylation in Mouse Lung Carcinogenesis<br \/>\nAdvisors: J. Carl Barrett and Theodora R. Devereux<\/p>\n<p><b>Arlene S. Pereira, Ph.D. <\/b><br \/>\nDissertation title: A Study of Antiretroviral Drug Penetration into the Male Genital Tract Using High Performance Liquid Chromatography and Tandem Mass Spectrometry<br \/>\nAdvisor: Richard R. Tidwell<\/p>\n<p><b>Kelly L. Price, M.S. <\/b><br \/>\nThesis title: Genetic Instability in Cervical Carcinogenesis<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<p><b>Michelle A. Rider, M.S. <\/b><br \/>\nThesis title: Suppression of Tumorigenicity in Rat Liver Tumor Cells by Human Chromosome 13: Evidence Against the Involvement of pRb<br \/>\nAdvisor: William B. Coleman<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1999<\/h2>\n<div style=\"text-align: left\">\n<p><b>Susannah Jo Bauman, Ph.D. <\/b><br \/>\nDissertation title: Antithrombotic Properties of Heparin Cofactor II<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Sharon King Bullock, Ph.D. <\/b><br \/>\nDissertation title: UV-Induced Inhibition of DNA Replication<br \/>\nAdvisor: Marila Cordeiro-Stone<\/p>\n<p><b>Tracey Dawson Cruz, Ph.D. <\/b><br \/>\nDissertation title: Chemokine Receptors in Inflammatory Disease: Studies Using Chemokine Receptor Knockout Mice<br \/>\nAdvisor: Nobuyo N. Maeda<\/p>\n<p><b>Vincent R. Torti, Ph.D. <\/b><br \/>\nDissertation title: Cellular Aging in Endometrial Stromal Cells Promotes the Growth of Immortalized and Carcinoma-derived Endometrial Epithelial Cells via Paracrine Interactions: The Role of Interleukin-1a and Interleukin-1b<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Cynthia Irvin Behe, M.S. <\/b><br \/>\nThesis title: Defective Cell Cycle Checkpoint Function in Transformed Hepatocytes and WB-F344 Hepatic Epithelial Stem-like Cells<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<\/div>\n<h2 style=\"text-align: center\">1998<\/h2>\n<div style=\"text-align: left\">\n<p><b>Julia T. Arnold, Ph.D. <\/b><br \/>\nDissertation title: Human Endometrial Stromal Cells Regulate Epithelial Cell Growth and Function In Vitro<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Shyra J. Crider-Miller, Ph.D. <\/b><br \/>\nDissertation title: Identification of Candidate Pediatric Tumor Suppressor Genes on Human Chromosome 11p15.5<br \/>\nAdvisor: Bernard E. Weissman<\/p>\n<p><b>Hitendra S. Jethwa, Ph.D. <\/b><br \/>\nDissertation title: Molecular Characterization of the Spontaneous Anti-Myeloperoxidase Antibody Response in SCG\/Kj Mice<br \/>\nAdvisor: J. Charles Jennette<\/p>\n<p><b>Donald W. Lawrence, Jr., Ph.D. <\/b><br \/>\nDissertation title: The Regulation of Human Neutrophil Adhesion and Spreading by 3&#8242;,5&#8242;-cyclic Guanosine Monophosphate<br \/>\nAdvisor: Katherine B. Pryzwansky<\/p>\n<p><b>Jonathan M. Phillips, Ph.D. <\/b><br \/>\nDissertation title: The Association of Specific DNA Sequences with the Nuclear Matrix During G0 and S Phases of the Cell Cycle<br \/>\nAdvisor: David G. Kaufman<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1997<\/h2>\n<div style=\"text-align: left\">\n<p><b>Laura L. (Neese) Glasscock, Ph.D. <\/b><br \/>\nDissertation title: Protein C Inhibitor: Structure-Activity Relationships and Pathobiological Aspects<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Paula M. Oliver, Ph.D. <\/b><br \/>\nDissertation title:Targeted Gene Titration of the Natriuretic Peptide Receptor A to Study Its Role in Essential Hypertension<br \/>\nAdvisor: Nobuyo N. Maeda<\/p>\n<p><b>Karen K. Phillips, Ph.D. <\/b><br \/>\nDissertation title: Identifying Suppressor Genes for Breast Cancer and Wilms Tumor<br \/>\nAdvisor: Bernard E. Weissman<\/p>\n<\/div>\n<h2 style=\"text-align: center\">1995<\/h2>\n<div style=\"text-align: left\">\n<p><b>Delores J. Grant, Ph.D. <\/b><br \/>\nDissertation title: Expression of the Haptoglobin Gene Complex<br \/>\nAdvisor: Nobuyo N. Maeda<\/p>\n<p><b>Steven C. Hoffman, M.S. <\/b><br \/>\nThesis title: Altered Expression of the p53 Tumor Suppressor Gene Enhances the Tumorigenic Potential of Neoplastically Transformed WB-F344 Rat Liver Epithelial Cells<br \/>\nAdvisor: Gary J. Smith<\/p>\n<p><b>Lara K. Surles, M.S. <\/b><br \/>\nThesis title: The Paradoxical Effects of Lovastatin, an HMGCoA Reductase Inhibitor, on Apolipoprotein E Deficient Mice<br \/>\nAdvisor: Nobuyo N. Maeda<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1994<\/h2>\n<div style=\"text-align: left\">\n<p><b>Chia Chiao, Ph.D. <\/b><br \/>\nDissertation title: Mechanisms of Promotion of Hepatocarcinogenesis in vitro<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<p><b>Suzanne L. Kirby, M.D., Ph.D. <\/b><br \/>\nDissertation title: Bone Marrow Stromal Proteoglycans and Their Roles in Hematopoiesis<br \/>\nAdvisor: Stuart A. Bentley<\/p>\n<p><b>Rebecca A. Shirk, Ph.D. <\/b><br \/>\nDissertation title:Structure-Function Studies of Heparin Binding Serpins<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Sunny H. Zhang, Ph.D. <\/b><br \/>\nDissertation title:An Animal Model of Atherosclerosis: The Apolipoprotein E Deficient Mice<br \/>\nAdvisor: Nobuyo N. Maeda<\/p>\n<p><b>Adella R. Clark, M.S. <\/b><br \/>\nThesis title: Immunogenetics of Inhibitor Response to FVIII:C<br \/>\nAdvisor: Howard M. Reisner<\/p>\n<p><b>Margaret M. Doherty, M.S. <\/b><br \/>\nThesis title: Regulation of the Epidermal Growth Factor Receptor in Rat Tracheal Epithelial Cells<br \/>\nAdvisor: Paul Nettesheim<\/p>\n<p><b>Julia K. Holtz, M.S. <\/b><br \/>\nThesis title: Defining the Functional Domains of the NaeI Restriction Endonuclease by Random Mutagenesis<br \/>\nAdvisor: Michael D. Topal<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1993<\/h2>\n<div style=\"text-align: left\">\n<p><b>Terry L. Blakenship-Paris, D.V.M.,Ph.D. <\/b><br \/>\nDissertation title:Clostridium difficile Enterocolitis Associated With an Atherogenic, High Fat Diet in Hamsters<br \/>\nAdvisor: Jerjang Chang<\/p>\n<p><b>Leah D. Fletcher, Ph.D. <\/b><br \/>\nDissertation title: Cloning and Characterization of Rat Derived Pneumocystis carinii Genes<br \/>\nAdvisor: Christine C. Dykstra<\/p>\n<p><b>Phillip (Andy) Futreal, Ph.D. <\/b><br \/>\nDissertation title: Physical Mapping of Tumor Suppressor Genes on Human Chromosomes 1q and 17q<br \/>\nAdvisor: J. Carl Barrett<\/p>\n<p><b>Debra K. McMahon, Ph.D. <\/b><br \/>\nDissertation title: Characterization of a Two Motif Isoform of the Dihydropyridine Receptor in Skeletal Muscle<br \/>\nAdvisor: Nadia N. Malouf<\/p>\n<p><b>Kimberly Weiss Schuenke, Ph.D. <\/b><br \/>\nDissertation title: Analysis of a Novel Protein Antigen Gene of Rickettsia Conorii<br \/>\nAdvisor: David H. Walker<\/p>\n<\/div>\n<h2 style=\"text-align: center\">1992<\/h2>\n<div style=\"text-align: left\">\n<p><b>Pengchin Chen, Ph.D. <\/b><br \/>\nDissertation title: Mapping of Tumor Suppressor Genes in Soft Tissue Sarcoma Cell Lines by Functional Analyses<br \/>\nAdvisor: Bernard E. Weismann<\/p>\n<p><b>Dean M. McCord, Ph.D. <\/b><br \/>\nDissertation title: Structure-Function Relationships in Human Coagulation Factor IX<br \/>\nAdvisor: Harold R. Roberts<\/p>\n<p><b>Joan P. Packenham, Ph.D. <\/b><br \/>\nDissertation title: Effect of Estradiol on Von Willebrand Factor Expression in Cultured Endothelial Cells<br \/>\nAdvisor: Cora-Jean S. Edgell<\/p>\n<p><b>Herbert C. Whinna, M.D., Ph.D. <\/b><br \/>\nDissertation title: Structure Function Studies on Heparin Cofactor II<br \/>\nAdvisor: Frank C. Church<\/p>\n<p><b>Todd A. Wyatt, Ph.D. <\/b><br \/>\nDissertation title: Neutrophil cGMP-Dependent Protein Kinase: Its Identification and Response to Formyl-Peptide and Calcium Ionophore<br \/>\nAdvisor: Katherine B. Pryzwansky<\/p>\n<p><b>Shelley L. Hoogstraten-Miller, D.V.M., M.S. <\/b><br \/>\nThesis title: Von Willebrand Factor in Plasma, Platelets, and Selected Tissues of Ferrets<br \/>\nAdvisor: Dwight Bellinger<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1991<\/h2>\n<div style=\"text-align: left\">\n<p><b>Linda A. Charles, Ph.D. <\/b><br \/>\nDissertation title: The Reactivity and Pathogenicity of Anti-Neutrophil Cytoplasmic Autoantibodies<br \/>\nAdvisor: J. Charles Jennette<\/p>\n<p><b>Daniel S. Marsman, Ph.D. <\/b><br \/>\nDissertation title: Peroxisome Proliferator Hepatocarcinogenesis in Rats: The Role of Cell Replication in Tumor Development<br \/>\nAdvisor: James A. Popp<\/p>\n<p><b>Ying Li, M.S. <\/b><br \/>\nThesis title: Repair of BPDE-DNA in Human Fibroblasts<br \/>\nAdvisor: William K. Kaufmann<\/p>\n<p><b>Thomas H. Rude, M.S. <\/b><br \/>\nThesis title: Cloning and Sequencing of the Cryptococcus neoformans NAD-dependent Mannitol Dehydrogenase Gene<br \/>\nAdvisor: Christine C. Dykstra<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1990<\/h2>\n<div style=\"text-align: left\">\n<p><b>Richard D. McFarland, Ph.D. <\/b><br \/>\nDissertation title: Mutagenesis in the Lambda Immunoglobulin Gene in a Human Lymphoblastoid Cell Strain<br \/>\nAdvisor: Gary J. Smith<\/p>\n<p><b>Linda L. Barrett, M.S. <\/b><br \/>\nThesis title: Five-Azacytidine Treatment Increases Anchorage Independent Growth of Human Endometrial Stromal Cells Expressing SV40 Large T Antigen<br \/>\nAdvisor: David G. Kaufman<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1989<\/h2>\n<div style=\"text-align: left\">\n<p><b>Mark Gregory Bolyard, Ph.D. <\/b><br \/>\nDissertation title: Characterization of Subunits of Human Fibrinogen Expressed in Escherichia coli<br \/>\nAdvisor: Susan T. Lord<\/p>\n<p><b>Richard James Rahija, Ph.D. <\/b><br \/>\nDissertation title: Factors Influencing the Initiation by Anti(+)benzo(a)pyrenediol-expoxide of Hepatocarcinogesis in the Male F344 Rat<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Jo Ann Tyndall, M.S. <\/b><br \/>\nThesis title: Azurophil and Specific Granule Exocytosis by N-formyl-methionyl-leucyl-phenylalanine-stimulated Human Neutrophils<br \/>\nAdvisor: Katherine B. Pryzwansky<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1988<\/h2>\n<div style=\"text-align: left\">\n<p><b>John James Dino, Jr., Ph.D. <\/b><br \/>\nDissertation title: Characterization of Radioactive &#8220;Early-eluting&#8221; Chromatographic Material Resulting from Interactions of Tritiated Benzo[a]pyrene With Liver Nucleic Acids in A\/HeJ Female Mice<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Brian G. Short, Ph.D. <\/b><br \/>\nDissertation title: Effects of Unleaded Gasoline on Renal Tubular Cell Kinetics and Tumor Promotion in Rats<br \/>\nAdvisor: James A. Swenberg<\/p>\n<p><b>Roc Bauman, M.S. <\/b><br \/>\nThesis title: Atherosclerosis in Hypercholesteerolemic Normal and von Willenrand&#8217;s Disease Swine<br \/>\nAdvisor: Thomas R. Griggs<\/p>\n<p><b>Russell C. Cattley, M.S., V.M.D., Ph.D. <\/b><br \/>\nThesis title: Peroxisome Proliferator Hepatocarcinogenesis in Rats<br \/>\nAdvisor: James A. Popp<\/p>\n<p><b>Romas Agu Vaitkus, M.S. <\/b><br \/>\nThesis title: Transformation of Human Endometrial Stromal Cells With a Temperature-sensitive, Origin-minus, SV40 Recombinant Plasmid<br \/>\nAdvisor: David G. Kaufman<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1987<\/h2>\n<div style=\"text-align: left\">\n<p><b>Mark de Serres, M.S. <\/b><br \/>\nThesis title: A Monoclonal Antibody Whose Binding is Inhibited by Divalent Cations<br \/>\nAdvisor: Howard M. Reisner<\/p>\n<p><b>Richard John Russell Lombardy, M.S. <\/b><br \/>\nThesis title: Computer-assisted Molecular Modeling Studies of Potent Amidine Inhibitors Bound to the Active Site of Trypsin<br \/>\nAdvisor: Richard R. Tidwell<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1986<\/h2>\n<div style=\"text-align: left\">\n<p><b>Norman A. Doggett, Ph.D. <\/b><br \/>\nDissertation title: The Temporal Order of Replication of Protooncogenes in Synchronized C3H 10T1\/2 Cells<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b><br \/>\nJeffrey Bruce Garris, M.S. <\/b><br \/>\nThesis title: Purified Human Factor VIII Procoagulant Protein: Comparative Hemostatic Response After Infusions into Hemophilic and von Willebrand Disease Dogs<br \/>\nAdvisor: Kenneth M. Brinkhous<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1985<\/h2>\n<div style=\"text-align: left\">\n<p><b>Karen Louise S. Bentley, Ph.D. <\/b><br \/>\nDissertation title: Cell Cycle-related Genotoxic Effects of 4-Nitroquinoline-1-oxide in C3H 10T1\/2 Cells<br \/>\nAdvisor: Joe W. Grisham<\/p>\n<p><b>Yung Sheng Eric Wang, Ph.D. <\/b><br \/>\nDissertation title: Plasma Free Fatty Acids: Development and Clinical Application of a New Analytical Method<br \/>\nAdvisor: William W. McLendon<\/p>\n<p><b>Michel G. Haddad, M.S. <\/b><br \/>\nThesis title: Idiotpy and Factor VIII Inhibitors: Towards the Production of a Monoclonal Anti-Idiotypic Antibody<br \/>\nAdvisor: Howard M. Reisner<\/p>\n<p><b>Otis Speight, M.S. <\/b><br \/>\nThesis title: Pathogenesis of Murine Infection Wtih Parainfluenza Virus in Mice: A Natural Paramyxovirus-Host Relationship<br \/>\nAdvisor: David H. Walker<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1984<\/h2>\n<div style=\"text-align: left\">\n<p><b>Tessie Brown McNeely, Ph.D. <\/b><br \/>\nDissertation title: Heparin: A Theory on Its In Vitro Anticoagulant Mechanism of Action<br \/>\nAdvisor: Michael J. Griffith<\/p>\n<p><b>Richard S. Paules, Ph.D. <\/b><br \/>\nDissertation title: An Investigation of the Effects of Exposure to a Chemical Carcinogen on DNA Replication in Mammalian Cells Utilizing Quantitative EM Visualization of Antibodies Bound to Carcinogen-DNA<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Bharat R. Gandhi, M.S. <\/b><br \/>\nThesis title: Production of Monoclonal Antibodies and Their Use in Characterization of Antigenic Proteins of Toxoplasma gondii Tachyzoites<br \/>\nAdvisor: G. Yancey Gillespie<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1983<\/h2>\n<div style=\"text-align: left\">\n<p><b>Samy Samuel Iskandar, M.D., Ph.D. <\/b><br \/>\nDissertation title: The Pathogenesis of Heterologous Protein-induced Glomerulonephritis: Studies in Inbred Mouse Strains<br \/>\nAdvisor: J. Charles Jennette<\/p>\n<p><b>James V. Lange, Ph.D. <\/b><br \/>\nDissertation title: Rickettsial Studies: Isolation and Quantitation of Rickettsiae in Patients With Rocky Mountain Spotted Fever and Production of Monoclonal Antibodies to Rickettsia rickettsii<br \/>\nAdvisor: David H. Walker<\/p>\n<p><b>Marjorie S. Read, Ph.D. <\/b><br \/>\nDissertation title: Venom Coagglutinin (VCA). The Platelet Aggregating Principle of Bothrops Venoms: Von Willibrand Factor-dependent Platelet Aggregation<br \/>\nAdvisor: Kenneth M. Brinkhous<\/p>\n<\/div>\n<h2 style=\"text-align: center\">1982<\/h2>\n<div style=\"text-align: left\">\n<p><b>Arthur Palfrey Bode, Ph.D. <\/b><br \/>\nDissertation title: Platelet Factor One in Human Platelets<br \/>\nAdvisor: Fred Dombrose<\/p>\n<p><b>Bruce Hugh Dorman, Jr., Ph.D. <\/b><br \/>\nDissertation title: Chemical Carcinogen Effects on Human Endometrium In Vitro: Phenotypic Alterations in Cell Cultures and Carcinogen Binding to DNA in organ Cultures<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Mary S. Baker, M.S. <\/b><br \/>\nThesis title: Alkylation of Deoxyribonucleotides and Their Role in Mutagenesis<br \/>\nAdvisor: Michael D. Topal<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1981<\/h2>\n<div style=\"text-align: left\">\n<p><b>Mary Ann Pregnall Lamb, Ph.D. <\/b><br \/>\nDissertation title: Immunochemical Studies on the Multimeric Structure of Factor VIII Related Antigen<br \/>\nAdvisor: Robert H. Wagner<\/p>\n<p><b>Gerald William Upton, D.D.S., M.S., Ph.D. <\/b><br \/>\nDissertation title: Platelet Inhibition and Thrombosis in the Pathogenesis of Bacterial Diseases<br \/>\nAdvisor: Frederic G. Dalldorf<\/p>\n<p><b>William Patrick Bennett, M.S. <\/b><br \/>\nThesis title: The Effects of an Extracellular Protease From Serratia marcescens on Membrane Functions of Human Platelets<br \/>\nAdvisor: Herbert A. Cooper<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1980<\/h2>\n<div style=\"text-align: left\">\n<p><b>Richard M. Lewis, Ph.D. <\/b><br \/>\nDissertation title: Studies on the Binding of Human Anti-Factor IX Antibodies to Factor IX Protein<br \/>\nAdvisor: Howard M. Reisner<\/p>\n<p><b>Marc J. Mass, Ph.D. <\/b><br \/>\nDissertation title: Species Differences in the Activation of a Carcinogen in Respiratory Epithelium: A Possible Explanation for the Unequal Susceptibilities of Tracheal Epithelium of Rats and Hamsters to Carcinogenesis by Benzo(a)pyrene<br \/>\nAdvisor: David G. Kaufman<\/p>\n<p><b>Michael S. Owens, Ph.D. <\/b><br \/>\nDissertation title: Marijuana Use Among Drivers in Fatal Single-vehicle Accidents<br \/>\nAdvisor: Arthur McBay<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1979<\/h2>\n<div style=\"text-align: left\">\n<p><b>Ronald Kent Charlton, Ph.D. <\/b><br \/>\nDissertation title: An Investigation of the Loss of Cytochrome P-450 From Cultured Hepatocytes<br \/>\nAdvisor: Joe W. Grisham<\/p>\n<p><b>William K. Kaufmann, Ph.D. <\/b><br \/>\nDissertation title: Studies of the Susceptibility of Hepatocytes in Specific Cell Cycle States to Carcinogenesis by N-Methyl-N-Nitrosourea<br \/>\nAdvisor: David G. Kaufman<\/p>\n<\/div>\n<h2 style=\"text-align: center\">1978<\/h2>\n<div style=\"text-align: left\">\n<p><b>Fernando A. Santos, M.D., Ph.D. <\/b><br \/>\nDissertation title: Purification and Characterization of Bovine Platelet Aggregating Factor (PAF): I: Purification of PAF. II: Immunological Characterization of PAF.<br \/>\nAdvisor: Robert H. Wagner<\/p>\n<p><b>Christine Norma Vogel, Ph.D. <\/b><br \/>\nDissertation title: In Vivo and In Vitro Biology of Antithrombin III and Thrombin<br \/>\nAdvisor: Roger L. Lundblad<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1975<\/h2>\n<div style=\"text-align: left\">\n<p><b>James Christian Lamb IV, J.D., Ph.D. <\/b><br \/>\nDissertation title: 1951-New Factors in the Regulation of Exocrine Pancreatic Secretion in the Rat<br \/>\nAdvisor: J.D. Geratz<\/p>\n<p><b>David Edward Sharp, M.D., Ph.D. <\/b><br \/>\nDissertation title: 1945-Morphologic Studies on Blood Platelet Response to Adenosine Diphosphate and Its Modification InVivo and In Vitro<br \/>\nAdvisor: Mason<\/p>\n<p><b>Sheryl Kathrein, M.S. <\/b><br \/>\nThesis title: A Comparison of Cryoprecipitate Yeilds by Different Methods<br \/>\nAdvisor: James E.T. Laningham<\/p>\n<p><b>Kenneth M. Lovette, M.S. <\/b><br \/>\nThesis title: The Subcellular Distribution and Partial Characteerization of Cholinesterase Activities in Canin Platelets<br \/>\nAdvisor: Hanson Chuang<\/p>\n<p><b>B. Alston Macon, Jr., M.S. <\/b><br \/>\nThesis title: Calcium Induced Conformational Changes in the Amino Acid Terminal End of Prothrombin<br \/>\nAdvisor: Koehler<\/p>\n<p><b>Gilbert C. White, M.D., M.S. <\/b><br \/>\nThesis title: The Effect of Various Anticoagulants on the Adhesiveness of Blood Platelets and Studies on the Mechanism of Platelet Adhesion.<br \/>\nAdvisor: Kenneth M. Brinkhous<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1974<\/h2>\n<div style=\"text-align: left\">\n<p><b>Daniel L. Leonard, M.S. <\/b><br \/>\nThesis title: Measurements of Chromium in Hair and Soft Tissue Using Flameless Atomic Absorption (FAA) Spectroscopy<br \/>\nAdvisor: Robert A. Goyer<\/p>\n<p><b>Daniel L. Leonard, M.S. <\/b><br \/>\nThesis title: Metabolic Effects of Oral NTA and Equivalent Injection Dose Administration of NTA and EDTA in the Adult Rat<br \/>\nAdvisor: Robert A. Goyer<\/p>\n<p><b>Larry Paul Thornburg, L.P., D.V.M., M.S. <\/b><br \/>\nThesis title: Direct Enzyme Cytochemical Investigation of the Trigeminal Ganglion of C57BL\/6J-dtj Mice and Their Littermates With an Hereditary Sensory Neuropathy (Dystonia Musculorum)<br \/>\nAdvisor: Stowe\/Hanker<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1972<\/h2>\n<div style=\"text-align: left\"><b>Dolph Oliver Adams, M.D., Ph.D. <\/b><br \/>\nDissertation title: The Differentiation of Mononuclear Phagocytes In Vivo: A Correlated Histologic and Fine Structural Study<br \/>\nAdvisor: Kenneth M. Brinkhous<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1971<\/h2>\n<div style=\"text-align: left\">\n<p><b>Waykin Nopanitaya, Ph.D. <\/b><br \/>\nThesis title: Effects of the Pungent Principle of Hot Red Pepper (Capsaicin) in Combination With Diets of Varying Protein Content on the Duodenal Absorptive Cells and the Growth of the Rat<br \/>\nAdvisor: Sylvanus W. Nye<\/p>\n<p><b>George Peter Wysocki, D.D.S., Ph.D. <\/b><br \/>\nDissertation title: Synovial Membrane Changes in Hemophilic Arthopathy: A Light, Transmission and Scanning Electron Microscope Study<br \/>\nAdvisor: Kenneth M. Brinkhous<\/p>\n<p><b>Douglas Edward Mooreside, M.D., M.S. <\/b><br \/>\nThesis title: The Effects of Adenine on the Clotting Factors in Fresh Blood, Stored Blood, and Stored Fresh Frozen Plasma<br \/>\nAdvisor: James E.T. Laningham<\/p>\n<p><b>Robert L. Reddick, M.D., M.S. <\/b><br \/>\nThesis title: Thrombocytopenia of Hibernation: With Special Reference to the Role of the Spleen.<br \/>\nAdvisor: Penick<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1970<br \/>\n<b> <\/b><\/h2>\n<div style=\"text-align: left\">\n<p><b>Joe Paul Hurt, M.D., M.S., Ph.D. <\/b><br \/>\nDissertation title: Dynamics of Diffuse Introvascular Coagulation Associated With an Experimental Glioma<br \/>\nAdvisor: Krigman<\/p>\n<p><b>Hussian Ismail Saba, M.D., Ph.D. <\/b><br \/>\nDissertation title: Effects of Polymorphonuclear Leukocytes on Blood Coagulation and Fibrinolysis<br \/>\nAdvisor: Harold R. Roberts<\/p>\n<p><b>Paul deVendel Davis, J.D., M.S. <\/b><br \/>\nThesis title: The Heterozygote for Hemophilia A and B: A Coagulation and Genetic Study<br \/>\nAdvisor: Kenneth M. Brinkhous<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1969<\/h2>\n<div style=\"text-align: left\">\n<p><b>Theodore Hyde Kiesselbach, M.D., Ph.D. <\/b><br \/>\nDissertation title: Coagulation Factor XIII: A Thrombin-labile Protein in Plasma, Platelets, and Bone Marrow Megakaryocytes<br \/>\nAdvisor: Robert H. Wagner<\/p>\n<p><b>Mohammad A. Nadjem, M.D., M.S. <\/b><br \/>\nThesis title: A Study of the Anatomical Pathology of Liver Fluke Infestation (Opisthorchis viverrini) in Thai<br \/>\nAdvisor: Sylvanus W. Nye<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1968<\/h2>\n<div style=\"text-align: left\"><b>William Phillip Webster, D.D.S., M.S. <\/b><br \/>\nThesis title: Studies of In Vivo and Ex Vivo Release of Factor VIII From Organs and Tissues<br \/>\nAdvisor: Penick<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1967<\/h2>\n<div style=\"text-align: left\">\n<p><b>Roy Vernon Land, M.D., M.S. <\/b><br \/>\nThesis title: A Study of Some Effects of E. coli Endotoxin on Rabbit Blood Platelets<br \/>\nAdvisor: Kenneth M. Brinkhous<\/p>\n<p><b>William Dumas McLester, M.D., Ph.D. <\/b><br \/>\nDissertation title: Studies on Circulating Anticoagulants in Classical Hemophilia and Christmas Disease<br \/>\nAdvisor: Robert H. Wagner<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1965<\/h2>\n<div style=\"text-align: left\">\n<p><b>Ernesto A. deVeyra, Jr., M.D., M.S. <\/b><br \/>\nThesis title: Nerve Fiber Lesions in the Brain Stem Following Head Injury<br \/>\nAdvisor: Margaret C. Swanton<\/p>\n<p><b>Joe Paul Hurt, M.D., M.S. <\/b><br \/>\nThesis title: Further Purification of Beta Alanine Precipitated Human Antihemophilic Factor (AHF) by Adsorption or Reprecipitation<br \/>\nAdvisor: Robert H. Wagner<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1964<\/h2>\n<div style=\"text-align: left\"><b>Reginald Gladstone Mason, M.D., M.S. <\/b><br \/>\nThesis title: 1933-Studies on the Platelet Agglutinating Activity of Recalcified Normal and Pathologic Human Plasmas<br \/>\nAdvisor: Kenneth M. Brinkhous<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1959<\/h2>\n<div style=\"text-align: left\"><b>Perry F. Harris, M.D., D.V.M., M.S. <\/b><br \/>\nThesis title: Hemophilic Heterozygotes: A Reevaluation of the Concentration of Antihemophilic Factor in Their Plasma<br \/>\nAdvisor: Robert H. Wagner<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1958<\/h2>\n<div style=\"text-align: left\"><b>E. Carwile LeRoy, M.D., M.S. <\/b><br \/>\nThesis title: 1933-Historical and Experimental Studies of the Spontaneous Agglutination of Mammalian Blood Platelets<br \/>\nAdvisor: Kenneth M. Brinkhous<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1957<\/h2>\n<div style=\"text-align: left\"><b>Robert A. Farrell, M.D., M.S. <\/b><br \/>\nThesis title: A Study of Some Tosyl-Arginine and Acetyl-Tyrosine Esterases and Their Relationship to the Coagulation of Blood<br \/>\nAdvisor: Robert H. Wagner<\/div>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center\">1954<\/h2>\n<p style=\"text-align: left\"><b>George Elton Cox, M.D., M.S. <\/b><br \/>\nThesis title: Cholesterol in Atheroschlerosis: Studies on its Biosynthesis<br \/>\nAdvisor: C. Bruce Taylor<\/p>\n<\/div>\n<\/div>\n<p style=\"text-align: center\"><a class=\"internal-link\" title=\"\" href=\"https:\/\/www.med.unc.edu\/pathology\/mcp\/pbts\/\" target=\"_self\" rel=\"noopener noreferrer\">Pathobiology and Translational Science Graduate Program<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Graduates of the Pathobiology and Translational Science Graduate Program 2023 Mattew Combs, Ph.D. Dissertation title: The Role of GRAF RhoA-GAPs in Maintaining Highly Energetic Tissues via Regulation of Mitochondrial Quality Control Advisor: Joan Taylor Cherise Glodowski, Ph.D. Dissertation title: Identification of Intra-tumoral Heterogeneity, Drug-Induced Cellular Subpopulation Shifts, and novel metabolic Profiles in Triple Negative Breat &hellip; <a href=\"https:\/\/www.med.unc.edu\/pathology\/mcp\/mcp\/pbts\/for-prospective-students\/alumni\/\" aria-label=\"Read more about Program Alumni\">Read more<\/a><\/p>\n","protected":false},"author":1382,"featured_media":0,"parent":3497,"menu_order":22,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2295","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Program Alumni - Doctoral and Post-doctoral Studies in Pathobiology and Translational Science<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/pathology\/mcp\/mcp\/pbts\/for-prospective-students\/alumni\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Program Alumni - Doctoral and Post-doctoral Studies in Pathobiology and Translational Science\" \/>\n<meta property=\"og:description\" content=\"Graduates of the Pathobiology and Translational Science Graduate Program 2023 Mattew Combs, Ph.D. Dissertation title: The Role of GRAF RhoA-GAPs in Maintaining Highly Energetic Tissues via Regulation of Mitochondrial Quality Control Advisor: Joan Taylor Cherise Glodowski, Ph.D. Dissertation title: Identification of Intra-tumoral Heterogeneity, Drug-Induced Cellular Subpopulation Shifts, and novel metabolic Profiles in Triple Negative Breat &hellip; 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