{"id":2407,"date":"2018-07-10T10:07:51","date_gmt":"2018-07-10T14:07:51","guid":{"rendered":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/?p=2407"},"modified":"2018-07-11T10:09:36","modified_gmt":"2018-07-11T14:09:36","slug":"researchers-clarify-role-of-mutations-in-glioblastoma","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/2018\/07\/researchers-clarify-role-of-mutations-in-glioblastoma\/","title":{"rendered":"Researchers clarify role of mutations in glioblastoma"},"content":{"rendered":"<header>\n<p id=\"description\" class=\".documentDescription\"><em>In a preclinical study, researchers led by UNC Lineberger&#8217;s Ryan Miller, MD, investigated whether the location of where the mutation occurred within the sequence of the PIK3CA gene affected the mutation\u2019s ability to help drive cancerous growth. They also evaluated whether the location of the mutation would affect the cancer&#8217;s response to certain treatments.<\/em><\/p>\n<\/header>\n<div id=\"viewlet-above-content-body\"><\/div>\n<div id=\"content-area\">\n<div id=\"parent-fieldname-text\" class=\"plain\">\n<div id=\"parent-fieldname-text\" class=\"plain\">\n<p>Read more about this important discovery at the\u00a0<a class=\"external-link\" title=\"\" href=\"https:\/\/unclineberger.org\/news\/gene-mutations-promote-glioblastoma\" target=\"_self\">UNC\u00a0Lineberger\u00a0Comprehensive Cancer Center<\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>In a preclinical study, researchers led by UNC Lineberger&#8217;s Ryan Miller, MD, investigated whether the location of where the mutation occurred within the sequence of the PIK3CA gene affected the mutation\u2019s ability to help drive cancerous growth. They also evaluated whether the location of the mutation would affect the cancer&#8217;s response to certain treatments. Read &hellip; <a href=\"https:\/\/www.med.unc.edu\/pathology\/millerlab\/2018\/07\/researchers-clarify-role-of-mutations-in-glioblastoma\/\" aria-label=\"Read more about Researchers clarify role of mutations in glioblastoma\">Read more<\/a><\/p>\n","protected":false},"author":2049,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2407","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"featured_image":false,"featured_image_medium":false,"featured_image_medium_large":false,"featured_image_large":false,"featured_image_thumbnail":false,"featured_image_alt":false,"category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/posts\/2407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/users\/2049"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/comments?post=2407"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/posts\/2407\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/media?parent=2407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/categories?post=2407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pathology\/millerlab\/wp-json\/wp\/v2\/tags?post=2407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}