{"id":2229,"date":"2012-02-10T19:46:46","date_gmt":"2012-02-11T00:46:46","guid":{"rendered":"https:\/\/med.sites.unc.edu\/pathology\/taylorlab\/publications\/"},"modified":"2018-04-06T11:39:55","modified_gmt":"2018-04-06T15:39:55","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pathology\/taylorlab\/publications\/","title":{"rendered":"Selected Publications"},"content":{"rendered":"
\n

Click here for publications during affiliation with University of North Carolina, Chapel hill<\/span>
<\/a><\/p>\n

1. Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature.<\/a> <\/span>Cheng Z, Sundberg-Smith LJ, Mangiante LE, Sayers RL, Hakim ZS, Musunuri S, Maguire CT, Majesky MW, Zhou Z, <\/b>Mack CP, Taylor JM. Arterioscler Thromb Vasc Biol<\/span>. 2011 Oct;31(10):2193-202. Epub 2011 Jul 14<\/span><\/p>\n

2. Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype.<\/p>\n

Staus DP, Blaker AL, Medlin MD, Taylor JM, Mack CP.<\/p>\n

Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):360-7. Epub 2010 Nov 24.<\/p>\n

PMID:21106951<\/a><\/p>\n

3. Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation.<\/p>\n

Medlin MD, Staus DP, Dubash AD, Taylor JM, Mack CP.<\/p>\n

Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1779-86. Epub 2010 Aug 11.<\/p>\n

PMID:20702813 <\/a><\/p>\n

4. Focal adhesion kinase is essential for cardiac looping and multichamber heart formation.<\/p>\n

Doherty JT, Conlon FL, Mack CP, Taylor JM. Genesis. 2010 Aug;48(8):492-504.<\/p>\n

PMID:20572259<\/a><\/p>\n

5. PKA-dependent phosphorylation of serum response factor inhibits smooth muscle-specific gene expression.<\/p>\n

Blaker AL, Taylor JM, Mack CP. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2153-60. Epub 2009 Sep 24.<\/p>\n

PMID: 19778940<\/a><\/p>\n

6. Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth.<\/p>\n

DiMichele LA, Hakim ZS, Sayers RL, Rojas M, Schwartz RJ, Mack CP, Taylor JM.<\/p>\n

Circ Res. 2009 May 22;104(10):1201-8. Epub 2009 Apr 16.<\/p>\n

PMID: 19372463<\/a><\/p>\n

7. FAK regulates cardiomyocyte survival following ischemia\/reperfusion.<\/p>\n

Hakim ZS, DiMichele LA, Rojas M, Meredith D, Mack CP, Taylor JM.<\/p>\n

J Mol Cell Cardiol. 2009 Feb;46(2):241-8. Epub 2008 Nov 5.<\/p>\n

PMID: 19028502<\/a><\/p>\n

8. FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury.<\/p>\n

Sayers RL, Sundberg-Smith LJ, Rojas M, Hayasaka H, Parsons JT, Mack CP, Taylor JM.<\/p>\n

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2115-22. Epub 2008 Sep 11.<\/p>\n

PMID: 18787183<\/a><\/p>\n

9. Regulation of myocardin factor protein stability by the LIM-only protein FHL2.<\/p>\n

Hinson JS, Medlin MD, Taylor JM, Mack CP.<\/p>\n

Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1067-H1075. Epub 2008 Jun 27.<\/p>\n

PMID: 18586895<\/a><\/p>\n

10. The LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcription.<\/p>\n

Sundberg-Smith LJ, DiMichele LA, Sayers RL, Mack CP, Taylor JM.<\/p>\n

Circ Res. 2008 Jun 20;102(12):1502-11. Epub 2008 May 22.<\/p>\n

PMID: 18497331<\/a><\/p>\n

11. The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression.<\/p>\n

Lockman K, Taylor JM, Mack CP.<\/p>\n

Circ Res. 2007 Dec 7;101(12):e115-23. Epub 2007 Nov 8.<\/p>\n

PMID: 17991879<\/a><\/p>\n

12. Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment.<\/p>\n

Hakim ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Brackhan J, Smithies O, Mack CP, Taylor JM.<\/p>\n

Mol Cell Biol. 2007 Aug;27(15):5352-64. Epub 2007 May 25.<\/p>\n

PMID: 17526730<\/a><\/p>\n

13. Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors.<\/p>\n

Staus DP, Blaker AL, Taylor JM, Mack CP.<\/p>\n

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):478-86. Epub 2006 Dec 14.<\/p>\n

PMID:17170370<\/a> [PubMed – indexed for MEDLINE] Free Article Related citations<\/p>\n

14. Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors.<\/p>\n

Hinson JS, Medlin MD, Lockman K, Taylor JM, Mack CP.<\/p>\n

Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1170-80. Epub 2006 Sep 22.<\/p>\n

PMID: 16997888<\/a><\/p>\n

15. Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy.<\/p>\n

DiMichele LA, Doherty JT, Rojas M, Beggs HE, Reichardt LF, Mack CP, Taylor JM.<\/p>\n

Circ Res. 2006 Sep 15;99(6):636-45. Epub 2006 Aug 10.<\/p>\n

PMID: 16902179 <\/a><\/p>\n

16. Adhesion stimulates direct PAK1\/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation.<\/p>\n

Sundberg-Smith LJ, Doherty JT, Mack CP, Taylor JM.<\/p>\n

J Biol Chem. 2005 Jan 21;280(3):2055-64. Epub 2004 Nov 12.<\/p>\n

PMID: 15542607<\/a><\/p>\n

17. Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors.<\/p>\n

Lockman K, Hinson JS, Medlin MD, Morris D, Taylor JM, Mack CP.<\/p>\n

J Biol Chem. 2004 Oct 8;279(41):42422-30. Epub 2004 Aug 3.<\/p>\n

PMID: 15292266<\/a><\/p>\n

18. An endogenous inhibitor of focal adhesion kinase blocks Rac1\/JNK but not Ras\/ERK-dependent signaling in vascular smooth muscle cells.<\/p>\n

Sundberg LJ, Galante LM, Bill HM, Mack CP, Taylor JM.<\/p>\n

J Biol Chem. 2003 Aug 8;278(32):29783-91. Epub 2003 Jun 2.<\/p>\n

PMID: 12782622<\/a><\/p>\n

19. Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells.<\/p>\n

Taylor JM, Mack CP, Nolan K, Regan CP, Owens GK, Parsons JT.<\/p>\n

Mol Cell Biol. 2001 Mar;21(5):1565-72.<\/p>\n

PMID: 11238893<\/a><\/p>\n

20. Characterization of graf, the GTPase-activating protein for rho associated with focal adhesion kinase. Phosphorylation and possible regulation by mitogen-activated protein kinase.<\/p>\n

Taylor JM, Hildebrand JD, Mack CP, Cox ME, Parsons JT.<\/p>\n

J Biol Chem. 1998 Apr 3;273(14):8063-70.<\/p>\n

PMID: 9525907<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Click here for publications during affiliation with University of North Carolina, Chapel hill 1. Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature. Cheng Z, Sundberg-Smith LJ, Mangiante LE, Sayers RL, Hakim ZS, Musunuri S, Maguire CT, Majesky MW, Zhou Z, Mack CP, Taylor JM. Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2193-202. Epub … Read more<\/a><\/p>\n","protected":false},"author":25022,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2229","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"\nSelected Publications - Joan Taylor Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/pathology\/taylorlab\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Selected Publications - Joan Taylor Lab\" \/>\n<meta property=\"og:description\" content=\"Click here for publications during affiliation with University of North Carolina, Chapel hill 1. Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature. Cheng Z, Sundberg-Smith LJ, Mangiante LE, Sayers RL, Hakim ZS, Musunuri S, Maguire CT, Majesky MW, Zhou Z, Mack CP, Taylor JM. Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2193-202. 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