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Journal Club: Adam Tabbaa – Opioid Associated Constipation

October 2, 2019 @ 8:00 am - 9:00 am

Have any of your patients ever experienced opioid-associated constipation?

For opioid-associated constipation, do you advise senna first, miralax first, or both agents in combination?

For opioid-associated constipation, when do you prescribe a peripherally acting,  mu-opioid antagonist such as methylnaltrexone or naloxegol?

This Wednesday at 8 am in the 5th floor old clinic conference room, Adam Tabbaa will be leading our journal club discussion of the following studies related to the management of opioid associated constipation.

Chey, W. D., Webster, L., Sostek, M., Lappalainen, J., Barker, P. N., & Tack, J. (2014). Naloxegol for opioid-induced constipation in patients with noncancer pain. New England Journal of Medicine, 370(25), 2387-2396.

Hawley, P., MacKenzie, H., & Gobbo, M. (2019). PEG vs. sennosides for opioid-induced constipation in cancer care. Supportive Care in Cancer, 1-8.

Hope you’ll be able to join us (and our fellowship candidates).

If you are unable to join in person, the call in number is (919) 962-2717.


Hosted by the UNC Comprehensive Cancer Support Program (CCSP) and the UNC Palliative Care Program.

We offer:


The School of Medicine of the University of North Carolina at Chapel Hill is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Continuing Medical Education Statement

The School of Medicine of the University of North Carolina at Chapel Hill designates this live activity for a maximum of 8.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other health professionals will receive a certificate of attendance from an AMA PRA Category 1™ activity. These certificates are accepted by the NC Boards for physician assistants, nurse practitioners, nurses, and respiratory therapists.  Other health care providers may also be able to use these certificates, depending on their particular license requirements.  (License requirements are subject to change. Participants should check with their licensing boards for specific questions.  UNC and its partners are not responsible for changes in license requirements.)

Disclosure statement

This activity has been planned and implemented under the sole supervision of the course director and planning committee, in association with the UNC Office of Continuing Professional Development (UNC CPD).  The course director, planning committee, presenters, and CPD staff have no relevant financial relationships with commercial interests as defined by the ACCME.


October 2, 2019
8:00 am - 9:00 am
Event Category: