{"id":2310,"date":"2020-11-12T11:13:52","date_gmt":"2020-11-12T16:13:52","guid":{"rendered":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/?page_id=2310"},"modified":"2026-03-12T09:15:48","modified_gmt":"2026-03-12T13:15:48","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<h2>2026<\/h2>\n<div>Herlihy L E, Collins C, Reilly K, et al. (March 06, 2026) <a href=\"https:\/\/www.cureus.com\/articles\/470302-decision-support-tools-strengthen-early-peanut-introduction-practices-and-streamline-data-automation#!\/\">Decision Support Tools Strengthen Early Peanut Introduction Practices and Streamline Data Automation.<\/a> Cureus 18(3): e104769. doi:10.7759\/cureus.104769<\/div>\n<div>\u00a0<\/div>\n<div>Sun T, Virkud YV, Kirpas M, Gregory K, De Paz J, O&#8217;Connell I, Yassour M, Shreffler W, Yuan Q, Martin V. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41220250\/\">Fecal calprotectin and other biomarkers are not prospectively associated with food protein-induced allergic proctocolitis<\/a>. J Pediatr Gastroenterol Nutr. 2026 Jan;82(1):42-49. doi: 10.1002\/jpn3.70257. Epub 2025 Nov 11. PMID: 41220250.<\/div>\n<div>\u00a0<\/div>\n<div>Wang Y, Zhang Y, Dudley C, Fitzgerald K, Carson AS, Kapita CM, Rana D, Kluckman K, Bortner D, Cowley DO, Travis CR, Vorobiov J, Choudhary S, Kepley CL, Commins SP, Smith SA, Iweala OI. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41534718\/\">Alpha-gal-specific human IgE promotes both alpha-gal-induced and antigen-independent allergic effector cell activation<\/a>. J Allergy Clin Immunol. 2026 Jan 12:S0091-6749(26)00001-1. doi: 10.1016\/j.jaci.2025.12.1007. Epub ahead of print. PMID: 41534718.<\/div>\n<div>\u00a0<\/div>\n<div>\n<h2>2025<\/h2>\n<\/div>\n<div>Singh N, Kesselring J, Humphrey J, Herlihy L, Burks AW, Smeekens J, Keet C, Bird JA, Kim EH, Kulis M. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41117056\/\">Peanut Component-Specific IgE and IgG4 Are Modulated by Sublingual Immunotherapy and Are Associated With Remission in 1-4-Year-Old Children<\/a>. Allergy. 2025 Oct 21. doi: 10.1111\/all.70111. Epub ahead of print. PMID: 41117056.<\/div>\n<div>\u00a0<\/div>\n<div>Smeekens JM, Kulis MD, Kim EH, Patil SU. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41030174\/\">Induction of tolerance to food allergens-Younger is better<\/a>. Pediatr Allergy Immunol. 2025 Oct;36(10):e70193. doi: 10.1111\/pai.70193. PMID: 41030174.<\/div>\n<div>\u00a0<\/div>\n<div><span class=\"authors\">Hosein EA, Virkud YV, Kim EH, Hoke MK, Thompson AL, Keet CA. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/40744377\/\" target=\"_blank\" rel=\"noopener\">Temporal, Age, and Racial and Ethnic Trends in Allergen Consumption from 2-Day 24-Hour Recalls, NHANES 2003-2023.\u00a0<\/a><span class=\"source\">J Allergy Clin Immunol Pract<\/span>.\u00a0<span class=\"pubdate\">2025 Jul 29;<\/span>.\u00a0<span class=\"doi\">doi: 10.1016\/j.jaip.2025.07.028.\u00a0<\/span><span class=\"pubstatus\">[Epub ahead of print]\u00a0<\/span><span class=\"pmid\">PubMed PMID: 40744377<\/span><span class=\"pmcid\">; PubMed Central PMCID: PMC12422817<\/span>.<\/div>\n<div>\u00a0<\/div>\n<div>Kulis M, Humphrey JR, Krempski JW, Kim EH, Smeekens JM. <a href=\"https:\/\/www.frontiersin.org\/journals\/immunology\/articles\/10.3389\/fimmu.2025.1617153\/full\">Anti-IgE therapy versus allergen-specific immunotherapy for food allergy: weighing the pros and cons<\/a>. Front. Immunol. 2025 July 21; doi: 10.3389\/fimmu.2025.1617153<\/div>\n<div>\u00a0<\/div>\n<div>Kim EH, Abrams EM. <a href=\"https:\/\/www.jaci-inpractice.org\/article\/S2213-2198(25)00186-2\/fulltext\">Meeting the Needs of the Changing Landscape of Food Allergy Management<\/a>. JACI in Practice. 2025 April; doi: 10.1016\/j.jaip.2025.02.015<\/div>\n<div>\u00a0<\/div>\n<div>Dantzer J, Virkud Y, Wang J, Sicherer S, Groetch M, Shreffler W, Pyle D, Kim E, Keet C, Kulis M, Mudd K, Sindher S, Long A, Scurlock AM, Jones SM, Leung D, Lanser B, Vickery B, Ezhuthachan ID, Bird JA, Parrish C, Spergel JM, Brown-Whitehorn T, Ligueros-Saylan M, Tassinari P, Iqbal A, Sibanda D, Huckabee C, Yovetich N, Rogers N, Lin A, Wheatley LM, Togias A, Chinthrajah RS, Wood RA.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40447195\/\"> Introduction of allergenic foods after treatment with omalizumab.<\/a> J Allergy Clin Immunol. 2025 May 28:S0091-6749(25)00608-6. doi: 10.1016\/j.jaci.2025.05.014. Epub ahead of print. PMID: 40447195; PMCID: PMC12232453.<\/div>\n<div>\u00a0<\/div>\n<div class=\"docsum-wrap\">\n<div class=\"docsum-content\">Bernstein JS, Canon N, Schein CH, Braun W, Negi SS, Tchekmedyian R, Pozzoli M, Kim EH, Kulis MD, Vu T, Liu W, Chen X, Dreskin SC. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40311815\/\">Fine resolution of the N-terminal IgE-binding epitope of Ara h 2: discovery of variants with enhanced IgE binding<\/a>. J Allergy Clin Immunol. 2025 Apr 29:S0091-6749(25)00464-6. doi: 10.1016\/j.jaci.2025.03.032. Epub ahead of print. PMID: 40311815.<\/p>\n<p><span class=\"authors\">Tilles SA, Adelman DC, Greenhawt M, Irani AM, Lieberman J, Mohideen P, Mustafa SS, Sampson HA, Shaker M, Sinder SB, Virkud YV, Anagnostou A.\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/40294846\/\">Barriers and Solutions to Optimal Food Allergy Prevention, Diagnostic, and Management Strategies.\u00a0<\/a><span class=\"source\">J Allergy Clin Immunol Pract<\/span>.\u00a0<span class=\"pubdate\">2025 Apr 26;<\/span>.\u00a0<span class=\"doi\">doi: 10.1016\/j.jaip.2025.04.030.\u00a0<\/span><span class=\"pubstatus\">[Epub ahead of print]\u00a0<\/span><span class=\"pmid\">PubMed PMID: 40294846<\/span>.<\/p>\n<\/div>\n<\/div>\n<p>Humphrey JR, Guo R, Yue X, Keet CA, Virkud YV, Bird JA, Burks AW, Kim EH, Smeekens JM, Kulis MD. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40245952\/\">Baseline basophil activation and early suppression is associated with clinical outcome after peanut sublingual immunotherapy<\/a>. J Allergy Clin Immunol. 2025 Apr 15:S0091-6749(25)00417-8. doi: 10.1016\/j.jaci.2025.04.010. Epub ahead of print. PMID: 40245952.<\/p>\n<p>Keet CA, Burks AW. <a href=\"https:\/\/evidence.nejm.org\/doi\/10.1056\/EVIDe2400448?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\">To Eat or Not to Eat &#8211; Oral Immunotherapy for High-Threshold Peanut Allergy<\/a>. NEJM Evid. 2025 Mar;4(3):EVIDe2400448. doi: 10.1056\/EVIDe2400448. Epub 2025 Feb 25. PMID: 39998307.<\/p>\n<p><span class=\"authors\">Immormino RM, Wang Y, Zhang Y, Kapita CM, Thomas KO, Carson AS, Kesselring J, Smeekens J, Kulis MD, Moran TP, Iweala OI.\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/40065718\/\">Deficiency of H3K27 histone demethylase UTX in T cells blunts allergic sensitization and anaphylaxis to peanut.\u00a0<\/a><span class=\"source\">Immunohorizons<\/span>.\u00a0<span class=\"pubdate\">2025 Feb 18;<\/span><span class=\"volume\">9<\/span><span class=\"issue\">(4)<\/span>.\u00a0<span class=\"doi\">doi: 10.1093\/immhor\/vlaf008.\u00a0<\/span><span class=\"pmid\">PubMed PMID: 40065718<\/span><span class=\"pmcid\">; PubMed Central PMCID: PMC11893976<\/span>.<\/p>\n<p><span class=\"authors\">Anagnostou A, Bird JA, Chinthrajah S, Dribin TE, Fleischer DM, Kim E, Nowak-Wegrzyn A, Rachid R, Shaker MS, Shreffler W, Sicherer S, Tam J, Vickery BP, Virkud YV, Wang J, Young M, Greenhawt M.\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39580718\/\">The use and implementation of omalizumab as food allergy treatment: Consensus-based guidance and Work Group Report of the Adverse Reactions to Foods Committee of the American Academy of Allergy, Asthma &amp; Immunology.\u00a0<\/a><span class=\"source\">J Allergy Clin Immunol<\/span>.\u00a0<span class=\"pubdate\">2025 Jan;<\/span><span class=\"volume\">155<\/span><span class=\"issue\">(1)<\/span><span class=\"pages\">:62-69.e1<\/span>.\u00a0<span class=\"doi\">doi: 10.1016\/j.jaci.2024.09.031.\u00a0<\/span><span class=\"pubstatus\">Epub 2024 Nov 22.\u00a0<\/span><span class=\"pmid\">PubMed PMID: 39580718<\/span><\/p>\n<h2>2024<\/h2>\n<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pai.14267\">Immunomodulatory metabolites in IgE-mediated food allergy and oral immunotherapy outcomes based on metabolomic profiling<\/a> Nov 2024 [Virkud]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39019435\/\">The availability of allergen-friendly food for college students experiencing food insecurity: Exploring current campus practices<\/a> Nov 2024 [Virkud]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39293782\/\">Omalizumab Implementation in Practice: Lessons Learned From the OUtMATCH Study<\/a> Nov 2024 [Keet, Kim]\n<p><a href=\"https:\/\/www.annallergy.org\/article\/S1081-1206(24)01556-4\/fulltext\">Community and academic allergists\u2019 perspectives on integrating biologics into food allergy care<\/a> Oct 2024 [Fisher, Kim]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674924004111?via%3Dihub\">A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice<\/a> Aug 2024 [Smeekens, Burks, Kulis]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674924003324?via%3Dihub\">Targeting inhibitory Siglec-3 to suppress IgE-mediated human basophil degranulation<\/a> Aug 2024 [Commins, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39168187\/#full-view-affiliation-7\">Indoor allergen exposure and its association to upper respiratory infections and pulmonary outcomes among children with asthma<\/a> Aug 2024 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38036248\/\">Rates of New Peanut Allergy and Discontinuation Following Introduction in High-Risk Infants<\/a> Mar 2024 [Keet]\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11193494\/\">Omalizumab for the Treatment of Multiple Food Allergies<\/a> Feb 2024 [Kim, Keet, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37804001\/\">Different airborne particulates trigger distinct immune pathways leading to peanut allergy in a mouse model<\/a> Feb 2024 [Immormimo, Smeekens, Mathai, Kulis, Moran]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38349368\/\">Management of Food Allergies and Food-Related Anaphylaxis<\/a> Feb 2024 [Virkud, Iweala]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37737994\/\">A Mouse Model of Shrimp Allergy with Cross-Reactivity to Crab and Lobster<\/a> 2024 [Smeekens, Kesselring, Kulis]\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><a class=\"btn btn-primary btn-lg  oscitas-bootstrap-container\" target=\"_self\" href=\"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/research\/publications\/past-publications\/\">Past publications<\/a>\n","protected":false},"excerpt":{"rendered":"<p>2026 Herlihy L E, Collins C, Reilly K, et al. (March 06, 2026) Decision Support Tools Strengthen Early Peanut Introduction Practices and Streamline Data Automation. Cureus 18(3): e104769. doi:10.7759\/cureus.104769 \u00a0 Sun T, Virkud YV, Kirpas M, Gregory K, De Paz J, O&#8217;Connell I, Yassour M, Shreffler W, Yuan Q, Martin V. Fecal calprotectin and other &hellip; <a href=\"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/\" aria-label=\"Read more about Publications\">Read more<\/a><\/p>\n","protected":false},"author":104407,"featured_media":0,"parent":2288,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2310","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Publications - UNC Food Allergy Initiative<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - UNC Food Allergy Initiative\" \/>\n<meta property=\"og:description\" content=\"2026 Herlihy L E, Collins C, Reilly K, et al. (March 06, 2026) Decision Support Tools Strengthen Early Peanut Introduction Practices and Streamline Data Automation. Cureus 18(3): e104769. doi:10.7759\/cureus.104769 \u00a0 Sun T, Virkud YV, Kirpas M, Gregory K, De Paz J, O&#8217;Connell I, Yassour M, Shreffler W, Yuan Q, Martin V. 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(March 06, 2026) Decision Support Tools Strengthen Early Peanut Introduction Practices and Streamline Data Automation. Cureus 18(3): e104769. doi:10.7759\/cureus.104769 \u00a0 Sun T, Virkud YV, Kirpas M, Gregory K, De Paz J, O&#8217;Connell I, Yassour M, Shreffler W, Yuan Q, Martin V. Fecal calprotectin and other &hellip; Read more","og_url":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/","og_site_name":"UNC Food Allergy Initiative","article_modified_time":"2026-03-12T13:15:48+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/","url":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/","name":"Publications - UNC Food Allergy Initiative","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/#website"},"datePublished":"2020-11-12T16:13:52+00:00","dateModified":"2026-03-12T13:15:48+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/"},{"@type":"ListItem","position":2,"name":"Laboratory Research","item":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/"},{"@type":"ListItem","position":3,"name":"Publications"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/#website","url":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/","name":"UNC Food Allergy Initiative","description":" Department of Pediatrics","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/pages\/2310","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/users\/104407"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/comments?post=2310"}],"version-history":[{"count":8,"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/pages\/2310\/revisions"}],"predecessor-version":[{"id":4344,"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/pages\/2310\/revisions\/4344"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/pages\/2288"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/wp-json\/wp\/v2\/media?parent=2310"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}