{"id":3679,"date":"2024-05-24T15:14:49","date_gmt":"2024-05-24T19:14:49","guid":{"rendered":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/?page_id=3679"},"modified":"2026-03-12T09:16:43","modified_gmt":"2026-03-12T13:16:43","slug":"past-publications","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/past-publications\/","title":{"rendered":"Past Publications"},"content":{"rendered":"<h2>2023<\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36828080\/\">Open-label study of the efficacy, safety, and durability of peanut sublingual immunotherapy in peanut allergic children<\/a> Jun 2023 [Kim, Keet, Virkud, Penumarti, Smeekens, Guo, Yue, Kulis, Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37771674\/\">The SunBEAm birth cohort: Protocol design<\/a> Aug 2023 [Keet, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37227666\/\">Environmental Exposure to Foods as a Risk Factor for Food Allergy<\/a> Aug 2023 [Turner, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37437951\/\">A single priming event prevents oral tolerance to peanut<\/a> Sep 2023 [Smeekens, Kesselring, Turner, Kulis, Moran]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37815782\/\">Desensitization and remission after peanut sublingual immunotherapy in 1-to-4-year-old peanut-allergic children: A randomized, placebo-controlled trial<\/a> Oct 2023 [Kim, Keet, Virkud, Herlihy, Smeekens, Guo, Yue, Penumarti, Kulis, Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37852442\/\">Frequency and predictors of multisystem reactions to peanut in infant oral food challenges<\/a> Oct 2023 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37943208\/\">IgE to common food allergens is associated with cardiovascular mortality in the National Health and Examination Survey and the Multi-Ethnic Study of Atherosclerosis<\/a> Nov 2023 [Keet]\n<h2><span style=\"color: #000000\">2022<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36243403\/\" target=\"_blank\" rel=\"noopener\">Home Introduction of Baked Egg after Oral Food Challenge<\/a> Oct 2022 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36248809\/\" target=\"_blank\" rel=\"noopener\">Novel peanut-specific human IgE monoclonal antibodies enable screens for inhibitors of the effector phase in food allergy<\/a> Sept 2022 [Burks, Guo, Iweala, Kulis, Suber, Ye, Zhang]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35470039\/\" target=\"_blank\" rel=\"noopener\">Preventing allergies through the skin<\/a> Sept 2022 [Keet, Winslow]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36089900\/\" target=\"_blank\" rel=\"noopener\">Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans<\/a> Sept 2022 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36138438\/\" target=\"_blank\" rel=\"noopener\">Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis<\/a> Sept 2022 [Virkud]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35718283\/\" target=\"_blank\" rel=\"noopener\">Peanut anaphylaxis in 2022: Decoupling epinephrine usage from emergency department evaluation<\/a> Sept 2022 [Kim, Winslow]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35998790\/\" target=\"_blank\" rel=\"noopener\">Treatment for food allergy: Current status and unmet needs<\/a> Aug 2022 [Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35944894\/\" target=\"_blank\" rel=\"noopener\">Peanut-Specific IgG4 and IgA in Saliva Are Modulated by Peanut Oral Immunotherapy<\/a> Aug 2022 [Burks, Kim, Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35490903\/\" target=\"_blank\" rel=\"noopener\">A &#8220;LEAP&#8221; forward in understanding immune mechanisms of oral tolerance to peanut<\/a> Aug 2022 [Kulis, Moran]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35990748\/\" target=\"_blank\" rel=\"noopener\">Single-dose AAV vector gene immunotherapy to treat food allergy<\/a> July 2022 [Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34848381\/\" target=\"_blank\" rel=\"noopener\">Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results<\/a> July 2022 [Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35839842\/\" target=\"_blank\" rel=\"noopener\">Targeting CD22 on memory B cells to induce tolerance to peanut allergens<\/a> July 2022 [Burks, Kulis, Hardy, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35123102\/\" target=\"_blank\" rel=\"noopener\">Evaluation of a group visit model for access to infant and toddler oral food challenges<\/a> Jun 2022 [Virkud]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35772597\/\" target=\"_blank\" rel=\"noopener\">Comparative efficacy of mepolizumab, benralizumab, and dupilumab in eosinophilic asthma: A Bayesian network meta-analysis<\/a> Jun 2022 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35657971\/\" target=\"_blank\" rel=\"noopener\">Comprehensive home environmental intervention did not reduce allergen concentrations or controller medication requirements among children in Baltimore<\/a> Jun 2022 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35026206\/\" target=\"_blank\" rel=\"noopener\">Updating the CoFAR Grading Scale for Systemic Allergic Reactions in Food Allergy<\/a> Jun 2022 [Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34971646\/\" target=\"_blank\" rel=\"noopener\">Safety of peanut (Arachis hypogaea) allergen powder-dnfp in children and teenagers with peanut allergy: Pooled summary of phase 3 and extension trials<\/a> Jun 2022 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35716952\/\" target=\"_blank\" rel=\"noopener\">Kinetics of basophil hyporesponsiveness during short-course peanut oral immunotherapy<\/a> Jun 2022 [Burks, Guo, Hamilton, Herlihy, Keet, Kim, Kulis, Li, Smeekens, Ye, Yue]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35285103\/\" target=\"_blank\" rel=\"noopener\">Prospective associations between acid suppressive therapy and food allergy in early childhood<\/a> May 2022 [Virkud]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34740607\/\" target=\"_blank\" rel=\"noopener\">Efficacy and safety of baked milk oral immunotherapy in children with severe milk allergy: A randomized, double-blind, placebo-controlled phase 2 trial<\/a> Apr 2022 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34864188\/\" target=\"_blank\" rel=\"noopener\">Effective methods of clinical education<\/a> Mar 2022 [Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35031274\/\" target=\"_blank\" rel=\"noopener\">The year in food allergy<\/a> Mar 2022 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34653515\/\" target=\"_blank\" rel=\"noopener\">Allergen-specific T cells and clinical features of food allergy: Lessons from CoFAR immunotherapy cohorts<\/a> Apr 2022 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35065784\/\" target=\"_blank\" rel=\"noopener\">Efficacy and safety of oral immunotherapy in children aged 1-3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study<\/a> Jan 2022 [Burks, Kim, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34530176\/\" target=\"_blank\" rel=\"noopener\">Bringing the Next Generation of Food Allergy Diagnostics Into the Clinic<\/a> Jan 2022 [Kulis]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2021<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35387036\/\" target=\"_blank\" rel=\"noopener\">Mouse Models of Food Allergy in the Pursuit of Novel Treatment Modalities<\/a> Dec 2021 [Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34818647\/\" target=\"_blank\" rel=\"noopener\">Mapping Sequential IgE-Binding Epitopes on Major and Minor Egg Allergens<\/a> Nov 2021 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34111450\/\" target=\"_blank\" rel=\"noopener\">The airway as a route of sensitization to peanut: An update to the dual allergen exposure hypothesis<\/a> Sept 2021 [Kulis, Moran, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33965597\/\" target=\"_blank\" rel=\"noopener\">Heterogeneity in Parent Preferences for Peanut Desensitization Therapy<\/a> Sept 2021 [Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34474713\/\" target=\"_blank\" rel=\"noopener\">Caregiver perceptions and attitudes associated with oral immunotherapy on social media<\/a> Sept 2021 [Keet]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33359589\/\" target=\"_blank\" rel=\"noopener noreferrer\">Continuous and Daily Oral Immunotherapy for Peanut Allergy: Results from a 2-Year Open-Label Follow-On Study<\/a> May 2021 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33966899\/\" target=\"_blank\" rel=\"noopener noreferrer\">Shorter &#8220;time to peanut introduction&#8221; can prevent peanut allergy and avert false Ara h 2 screening results in infants<\/a> May 2021 [Iglesia, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33966874\/\" target=\"_blank\" rel=\"noopener noreferrer\">Increasing diversity in peanut oral immunotherapy research and accessibility<\/a> May 2021 [Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33290772\/\" target=\"_blank\" rel=\"noopener noreferrer\">Epicutaneous immunotherapy for treatment of peanut allergy: Follow-up from the Consortium for Food Allergy Research<\/a> Mar 2021 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33542716\/\" target=\"_blank\" rel=\"noopener noreferrer\">Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice<\/a> Jan 2021 [Burks, Hinton, Kesselring, Kulis, Smeekens, Steinbach]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32980426\/\" target=\"_blank\" rel=\"noopener\">Timing of exposure to environmental adjuvants is critical to mitigate peanut allergy<\/a> Jan 2021 [Kulis, Moran, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33537245\/\" target=\"_blank\" rel=\"noopener noreferrer\">Current Insights into Immunotherapy Approaches for Food Allergy<\/a> Jan 2021 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32707238\/\">Five-year follow-up of early intervention peanut oral immunotherapy<\/a> Jan 2021 [Barber, Burks, Herlihy, Hamilton, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33417257\/\">Mechanisms of oral immunotherapy<\/a> Jan 2021 [Barshow, Burks, Kim, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33217614\/\" target=\"_blank\" rel=\"noopener\">Irradiated Tree Nut Flours for Use in Oral Immunotherapy<\/a> Jan 2021 [Burks, Kesselring, Kim, Kulis, Penumarti]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2020<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33380927\/\">Model of Walnut Allergy in CC027\/GeniUnc Mice Recapitulates Key Features of Human Disease<\/a> Dec 2020 [Kesselring, Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33380934\/\">Strategies for Mast Cell Inhibition in Food Allergy<\/a> Dec 2020 [Iweala, Suber]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32795587\/\" target=\"_blank\" rel=\"noopener noreferrer\">Early epitope-specific IgE antibodies are predictive of childhood peanut allergy<\/a> Nov 2020 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33217614\/\">Irradiated Tree Nut Flours for Use in Oral Immunotherapy<\/a> Nov 2020 [Burks, Kesselring, Kim, Kulis, Penumarti, Sheth]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33067325\/\">Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research<\/a> Oct 2020 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32535135\/\" target=\"_blank\" rel=\"noopener noreferrer\">Induction of sustained unresponsiveness after egg oral immunotherapy compared to baked egg therapy in children with egg allergy<\/a> Oct 2020 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32330666\/\">Dosing, safety, and quality of life after peanut immunotherapy trials: A long-term follow-up study<\/a> Sept 2020 [Barber, Burks, Herlihy, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32980426\/\">Timing of exposure to environmental adjuvants is critical to mitigate peanut allergy<\/a> Sept 2020 [Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32393770\/\" target=\"_blank\" rel=\"noopener noreferrer\">IgE producers in the gut expand the gut&#8217;s role in food allergy<\/a> Jul 2020 [Burks, Iweala]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32034781\/\" target=\"_blank\" rel=\"noopener noreferrer\">Food allergy immunotherapy: Oral immunotherapy and epicutaneous immunotherapy<\/a> Jun 2020 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31659757\/\" target=\"_blank\" rel=\"noopener noreferrer\">Legends of allergy and immunology: Hugh A. Sampson<\/a> Jun 2020 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31881232\/\" target=\"_blank\" rel=\"noopener noreferrer\">A 5-year summary of real-life dietary egg consumption after completion of a 4-year egg powder oral immunotherapy (eOIT) protocol<\/a> Apr 2020 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32220059\/\">Peanut applied to the skin of nonhuman primates induces antigen-specific IgG but not IgE<\/a> Mar 2020 [Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34109028\/\" target=\"_blank\" rel=\"noopener\">Systematic quantification of the dynamics of newly synthesized proteins unveiling their degradation pathways in human cells<\/a> Mar 2020 [Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31928251\/\" target=\"_blank\" rel=\"noopener noreferrer\">Immunotherapy approaches for peanut allergy<\/a> Feb 2020 [Burks, Kim, Patel]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31761123\/\" target=\"_blank\" rel=\"noopener\">Evolution of Immune Responses in Food Immunotherapy<\/a> Feb 2020 [Kulis, Smeekens]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2019<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31797153\/\">Biomarkers in Food Allergy Immunotherapy<\/a> Dec 2019 [Hardy, Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31789931\/\">A Novel Allergen-Specific Immune Signature-Directed Approach to Dietary Elimination in Eosinophilic Esophagitis<\/a> Dec 2019 [Burks, Guo, Hamilton, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31761123\/\">Evolution of Immune Responses in Food Immunotherapy<\/a> Nov 2019 [Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31437325\/\">IgE binding to linear epitopes of Ara h 2 in peanut allergic preschool children undergoing oral Immunotherapy<\/a> Oct 2019 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31493887\/\">Long-term sublingual immunotherapy for peanut allergy in children: Clinical and immunologic evidence of desensitization<\/a> Sep 2019 [Burks, Guo, Kim, Kulis, Ye]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31444814\/\">Indoor dust acts as an adjuvant to promote sensitization to peanut through the airway<\/a> Sep 2019 [Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31120555\/\" target=\"_blank\" rel=\"noopener noreferrer\">Clinical factors associated with peanut allergy in a high-risk infant cohort<\/a> Jul 2019 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31251968\/\">Plant cell-made protein antigens for induction of Oral tolerance<\/a> Jun 2019 [Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30886111\/\" target=\"_blank\" rel=\"noopener noreferrer\">The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing of Introduction of Allergenic Complementary Foods<\/a> Apr 2019 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30796610\/\">Hypoallergenic Proteins for the Treatment of Food Allergy<\/a> Feb 2019 [Kulis]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674918324874?via%3Dihub\">Dosing and Safety of Peanut Food Equivalents After Immunotherapy Trials<\/a> Feb 2019 [Barber, Burks, Herlihy, Kim]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674918324941?via%3Dihub\">Back to Life, Back to Reality \u2013 What Happens after Peanut Immunotherapy? A Long-Term Follow up Study on Perceptions of Safety and Lifestyle<\/a> Feb 2019 [Barber, Burks, Herlihy, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30586557\/\" target=\"_blank\" rel=\"noopener noreferrer\">The Consortium for Food Allergy Research (CoFAR): The first generation<\/a> Feb 2019 [Burks]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2018<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30383313\/\">Blocking antibodies induced by peanut oral and sublingual immunotherapy suppress basophil activation and are associated with sustained unresponsiveness<\/a> Nov 2018 [Burks, Guo, Hardy, Kulis, Smeekens, Suber]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30449234\/\" target=\"_blank\" rel=\"noopener noreferrer\">AR101 Oral Immunotherapy for Peanut Allergy<\/a> Nov 2018 [Burks, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30342892\/\">Genetic diversity between mouse strains allows identification of the CC027\/GeniUnc strain as an orally reactive model of peanut allergy<\/a> Oct 2018 [Burks, Guo, Kulis, Smeekens, Ye]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30417864\/\">Antigenic Liposomes for Generation of Disease-specific Antibodies<\/a> Oct 2018 [Hardy, Kulis, Smeekens]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30319619\/\">Adjuvanted Immunotherapy Approaches for Peanut Allergy<\/a> Sep 2018 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30126028\/\">High- and low-dose oral immunotherapy similarly suppress pro-allergic cytokines and basophil activation in young children<\/a> Sep 2018 [Burks, Guo, Kim, Kulis, Ye, Yue]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30075341\/\" target=\"_blank\" rel=\"noopener noreferrer\">Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research<\/a> Aug 2018 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29518422\/\" target=\"_blank\" rel=\"noopener noreferrer\">Egg-specific IgE and basophil activation but not egg-specific T-cell counts correlate with phenotypes of clinical egg allergy<\/a> Jul 2018 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29956142\/\">A Mouse Model of Peanut Allergy Induced by Sensitization Through the Gastrointestinal Tract<\/a> Jun 2018 [Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29408715\/\" target=\"_blank\" rel=\"noopener noreferrer\">Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector T H 2 subsets<\/a> Jun 2018 [Burks]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29700869\/\">Tree nut allergies: Allergen homology, cross-reactivity, and implications for therapy<\/a> Jun 2018 [Kulis, Smeekens]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674917327367?via%3Dihub\">Characteristics of Preschool-Aged Children Currently Enrolled in a Phase II Double Blind Placebo Controlled Study of Peanut Sublingual Immunotherapy<\/a> Feb 2018 [Burks, Herlihy, Kim]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674917325320?via%3Dihub\">A novel assessment of sustained unresponsiveness (SU) after long term sublingual immunotherapy (SLIT) in peanut allergic children: results of a 4 year phase II clinical trial<\/a> Feb 2018 [Bennick, Burks, Hamilton, Herlihy, Kim]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(17)32717-3\/fulltext\">Assessing the validity of an IRB approved REDCap web based clinical trials recruitment registry<\/a> Feb 2018 [Bennick, English, Hamilton, Herlihy, Kim]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2017<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29288078\/\">Immune mechanisms of oral immunotherapy<\/a> Dec 2017 [Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29192240\/\">Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy<\/a> Nov 2017 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28972089\/\">Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model<\/a> Sep 2017 [Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28927819\/\">Effect of endotoxin and alum adjuvant vaccine on peanut allergy<\/a> Sep 2017 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28709968\/\">Specific allergen profiles of peanut foods and diagnostic or therapeutic allergenic products<\/a> Jul 2017 [Commins, Kulis]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(16)31950-9\/fulltext\">Controlled Asthma Not Correlated with Respiratory Symptoms During DBPCFCs (Double Blind Placebo Controlled Food Challenges) to Peanut in Children<\/a> Feb 2017 [Bennick, Hamilton, Herlihy, Kim]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(16)31668-2\/fulltext\">Sublingual Peanut Immunotherapy: Role of Duration and Dose.<\/a> Feb 2017 [Bennick, Burks, Hamilton, Herlihy, Kim]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(16)32092-9\/fulltext\">Sustained Unresponsiveness After Sublingual Immunotherapy for Peanut-allergic Children<\/a> Feb 2017 [Bennick, Burks, Hamilton, Herlihy, Kim]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28132800\/\">Preparation and Analysis of Peanut Flour Used in Oral Immunotherapy Clinical Trials<\/a> Jan 2017 [ Burks, Kesselring, Kulis, Penumarti]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2016<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28017628\/\">Eosinophilic esophagitis during peanut oral immunotherapy with omalizumab<\/a> Dec 2016 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28801015\/\">Food allergen extracts to diagnose food-induced allergic diseases: How they are made<\/a> Nov 2016 [Burks, Penumarti]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27669462\/\">Mast cell desensitization inhibits calcium flux and aberrantly remodels actin<\/a> Sep 2016 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27554819\/\">Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2<\/a> Aug 2016 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27522159\/\">Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective<\/a> Aug 2016 [Burks, Guo, Kim, Kulis, Ye]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27015954\/\">Component-resolved analysis of IgA, IgE, and IgG4 during egg OIT identifies markers associated with sustained unresponsiveness<\/a> Jun 2016 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27039393\/\">Peanut Allergy: New Developments and Clinical Implications<\/a> May 2016 [Commins, Kim, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27108990\/\">The Seed Biotinylated Protein of Soybean (Glycine max): A Boiling-Resistant New Allergen (Gly m 7) with the Capacity To Induce IgE-Mediated Allergic Responses<\/a> May 2016 [Burks, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27130859\/\">Food-specific IgG 4 is associated with eosinophilic esophagitis<\/a> Apr 2016 [Burks, Guo, Kulis]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(15)02307-6\/fulltext\">NMR-Based Metabolomics Analysis Reproducibly Identifies Unique Subject-Specific Profiles That Change during Peanut Oral Immunotherapy<\/a> Feb 2016 [Burks, Hamilton, Kulis]\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091674915022848?via%3Dihub\">Basophil Activation and Peanut-Specific IgE Are Not Predictors of Threshold Dose during a Double-Blind Placebo-Controlled Food Challenge (DBPCFC)<\/a> Feb 2016 [Burks, Guo, Hamilton, Kim, Ye]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26362760\/\">Utility of component analyses in subjects undergoing sublingual immunotherapy for peanut allergy<\/a> Feb 2016 [Burks, Kim, Kulis]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2015<\/span><\/h2>\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(14)03227-8\/abstract\">High Rate of Sustained Unresponsiveness with Early-Intervention Peanut Oral Immunotherapy<\/a> Feb 2015 [Burks, Hamilton, Herlihy, Kim, Kulis]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(14)03228-X\/fulltext\">Peanut Sublingual Immunotherapy (SLIT) Results in Sustained Unresponsiveness in a Subset of Peanut Allergic Children<\/a> Feb 2015 [Burks, Hamilton, Guo, Kim, Kulis]\n<p><a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(14)02791-2\/fulltext\">Basophil Hyporesponsiveness Following Six Months of Peanut Oral Immunotherapy (OIT) Is Associated with Suppression of Syk Phosphorylation<\/a> Feb 2015 [Burks, Hamilton, Kulis, Yue]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2014<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24758688\/\">Novel strategy to create hypoallergenic peanut protein-polyphenol edible matrices for oral immunotherapy<\/a> May 2014 [Burks, Guo, Kulis]\n<hr class=\" rule-shadow osc-rule\" \/>\n<h2><span style=\"color: #000000\">2013<\/span><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23921317\/\">Allergenic properties of enzymatically hydrolyzed peanut flour extracts<\/a> Jul 2013 [Burks, Guo, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22795369\/\">Pepsinized cashew proteins are hypoallergenic and immunogenic and provide effective immunotherapy in mice with cashew allergy<\/a> Jul 2012 [Burks, Guo, Kulis]\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21377034\/\">A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response<\/a> Mar 2011 [Burks, Kulis, Yue]\n","protected":false},"excerpt":{"rendered":"<p>2023 Open-label study of the efficacy, safety, and durability of peanut sublingual immunotherapy in peanut allergic children Jun 2023 [Kim, Keet, Virkud, Penumarti, Smeekens, Guo, Yue, Kulis, Burks] The SunBEAm birth cohort: Protocol design Aug 2023 [Keet, Kim] Environmental Exposure to Foods as a Risk Factor for Food Allergy Aug 2023 [Turner, Smeekens] A single &hellip; <a href=\"https:\/\/www.med.unc.edu\/pediatrics\/foodallergy\/lab\/publications\/past-publications\/\" aria-label=\"Read more about Past Publications\">Read more<\/a><\/p>\n","protected":false},"author":20847,"featured_media":0,"parent":2310,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-3679","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This 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