{"id":4604,"date":"2026-01-05T10:57:32","date_gmt":"2026-01-05T15:57:32","guid":{"rendered":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/?p=4604"},"modified":"2026-01-05T15:40:00","modified_gmt":"2026-01-05T20:40:00","slug":"unc-research-highlights-promising-new-treatment-approach-for-hunter-syndrome","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/2026\/01\/unc-research-highlights-promising-new-treatment-approach-for-hunter-syndrome\/","title":{"rendered":"Renowned UNC Pediatric Biochemical Geneticist Leads First Study on a Novel Treatment for Hunter Syndrome"},"content":{"rendered":"<figure id=\"attachment_3052\" class=\"thumbnail wp-caption alignleft\" style=\"width: 255px\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-3052\" src=\"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2024\/07\/dr-muenzer-2-245x300.jpg\" alt=\"Dr. Muenzer\" width=\"245\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2024\/07\/dr-muenzer-2-245x300.jpg 245w, https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2024\/07\/dr-muenzer-2-768x942.jpg 768w, https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2024\/07\/dr-muenzer-2-600x736.jpg 600w, https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2024\/07\/dr-muenzer-2.jpg 800w\" sizes=\"auto, (max-width: 245px) 100vw, 245px\" \/><figcaption class=\"caption wp-caption-text\">Dr. Muenzer<\/figcaption><\/figure>\n<p>Ongoing clinical research at UNC could lead to a first-of-its-kind enzyme replacement therapy for Hunter syndrome, an ultra-rare disorder that causes progressive multisystem disease and neurologic decline.<\/p>\n<p>Joseph Muenzer, MD, PhD, the Director of the Muenzer MPS Research and Treatment Center and the Bryson Distinguished Professor in Pediatric Genetics at the UNC School of Medicine, served as the study\u2019s lead investigator for Denali Therapeutics\u2019 clinical trial.<\/p>\n<p data-start=\"939\" data-end=\"1115\">\u27a1\ufe0f Read the full press release: <a class=\"decorated-link\" href=\"https:\/\/news.unchealthcare.org\/2026\/01\/renowned-unc-pediatric-biochemical-geneticist-leads-first-study-on-a-novel-treatment-for-hunter-syndrome\/?utm_source=chatgpt.com\" target=\"_new\" rel=\"noopener\" data-start=\"971\" data-end=\"1115\">https:\/\/news.unchealthcare.org\/2026\/01\/renowned-unc-pediatric-biochemical-geneticist-leads-first-study-on-a-novel-treatment-for-hunter-syndrome\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ongoing clinical research at UNC could lead to a first-of-its-kind enzyme replacement therapy for Hunter syndrome, an ultra-rare disorder that causes progressive multisystem disease and neurologic decline. Joseph Muenzer, MD, PhD, the Director of the Muenzer MPS Research and Treatment Center and the Bryson Distinguished Professor in Pediatric Genetics at the UNC School of Medicine, &hellip; <a href=\"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/2026\/01\/unc-research-highlights-promising-new-treatment-approach-for-hunter-syndrome\/\" aria-label=\"Read more about Renowned UNC Pediatric Biochemical Geneticist Leads First Study on a Novel Treatment for Hunter Syndrome\">Read more<\/a><\/p>\n","protected":false},"author":119071,"featured_media":4596,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-4604","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2025\/12\/311a4f2c-72f2-44e7-817c-f61a4d7935f8.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2025\/12\/311a4f2c-72f2-44e7-817c-f61a4d7935f8-300x300.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2025\/12\/311a4f2c-72f2-44e7-817c-f61a4d7935f8-768x768.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2025\/12\/311a4f2c-72f2-44e7-817c-f61a4d7935f8-1024x1024.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-content\/uploads\/sites\/1312\/2025\/12\/311a4f2c-72f2-44e7-817c-f61a4d7935f8-150x150.jpg","featured_image_alt":"Dr. Joseph Muenzer","category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/posts\/4604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/users\/119071"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/comments?post=4604"}],"version-history":[{"count":6,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/posts\/4604\/revisions"}],"predecessor-version":[{"id":4611,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/posts\/4604\/revisions\/4611"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/media\/4596"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/media?parent=4604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/categories?post=4604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pediatrics\/muenzer-mps-center\/wp-json\/wp\/v2\/tags?post=4604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}