{"id":38927,"date":"2025-05-07T17:03:34","date_gmt":"2025-05-07T21:03:34","guid":{"rendered":"https:\/\/www.med.unc.edu\/pediatrics\/?post_type=tribe_events&#038;p=38927"},"modified":"2025-05-08T10:09:42","modified_gmt":"2025-05-08T14:09:42","slug":"childrens-research-institute-seminar-series-16","status":"publish","type":"tribe_events","link":"https:\/\/www.med.unc.edu\/pediatrics\/event\/childrens-research-institute-seminar-series-16\/","title":{"rendered":"Children&#8217;s Research Institute Seminar Series"},"content":{"rendered":"<h2 class=\"tribe-events-list-event-title\"><strong>Interleukin 6 regulation of T cell metabolism and function<\/strong><\/h2>\n<h3>Yazan Alwarawrah, PhD<\/h3>\n<h4>Assistant Professor, Pediatric Endocrinology<\/h4>\n<h3><strong>3116 Mary Ellen Jones <\/strong><\/h3>\n<h4 style=\"text-align: left\"><em>Lunch Provided<\/em><\/h4>\n<h5>or<\/h5>\n<h3><a href=\"https:\/\/zoom.us\/j\/98566446544?pwd=ajU0aFhvbGdZRlROZXN0Z1liMXlzZz09\" target=\"_blank\" rel=\"noopener\"><strong>JOIN THE ZOOM<\/strong><\/a><\/h3>\n<p>https:\/\/zoom.us\/j\/98566446544?pwd=ajU0aFhvbGdZRlROZXN0Z1liMXlzZz09<br \/>\n<strong><em>Please mute your microphone.<\/em><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.med.unc.edu\/pediatrics\/people\/yazan-alwarawrah-phd\/\" target=\"_blank\" rel=\"noopener\">Dr. Yazan Alwarawrah<\/a> is a Research Assistant Professor who is interested in targeting metabolism for the treatment of disease. Currently, he is studying T cell metabolism in the context of obesity-associated protective immunity dysfunction where he uses the diet induced obesity mouse model to study the effect of obesity on T cell metabolism and function in different tissues using metabolic and flow cytometric approaches. He is specifically interested in the role of T cell metabolic dysfunction in the impairment of protective immunity against influenza. He also works on studying Immunity Related GTPase I (Irgm1) regulation of T cell metabolism and function and its role in protective immunity and autoimmunity, and he works on the metabolic engineering of chimeric antigen receptor (CAR) T cells to enhance their persistence in the tumor microenvironment. He has a diverse scientific background ranging from molecular biology and bioinformatics to pharmacology and immunology. He seeks challenging questions in cellular metabolism and immunology that can lead to finding treatments for obesity associated pathologies, cancer, and autoimmune diseases.<\/p>\n<hr \/>\n<p>The School of Medicine of the University of North Carolina at Chapel Hill is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The School of Medicine of the University of North Carolina at Chapel Hill designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit(s) . Physicians should claim only the credit commensurate with the extent of their participation in the activity. This activity has been planned and implemented under the sole supervision of the course directors, (Dr. Toni Darville &amp; Dr. Corinne Keet), in association with the UNC Office of Continuing Professional Development (UNC CPD). The course directors, presenters, and CPD staff have no relevant financial relationships with commercial interests as defined by the ACCME.<\/p>\n<p>For CME Credit go to: <a href=\"https:\/\/www.med.unc.edu\/cpd\" target=\"_blank\" rel=\"noopener\">https:\/\/www.med.unc.edu\/cpd<\/a><br \/>\nUse activity code: 114046<br \/>\nFor questions email <a href=\"mailto:douglas_hudson@med.unc.edu\">douglas_hudson@med.unc.edu<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interleukin 6 regulation of T cell metabolism and function<br \/>\n&#8212;<br \/>\nYazan Alwarawrah, PhD<br \/>\nAssistant Professor, Pediatric Endocrinology<br \/>\n&#8212;<br \/>\n3116 Mary Ellen Jones (Lunch Provided)<br \/>\nor JOIN THE ZOOM<\/p>\n","protected":false},"author":3424,"featured_media":38842,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"tribe_events_cat":[135,180],"class_list":["post-38927","tribe_events","type-tribe_events","status-publish","has-post-thumbnail","hentry","tribe_events_cat-cri-seminar","tribe_events_cat-research-symposium","cat_cri-seminar","cat_research-symposium","odd"],"acf":[],"yoast_head":"<!-- This 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