Prof Michael O’Donovan is a clinical academic with dual qualifications in medicine (MBChB) and science (PhD). He is accredited to practice psychiatry (FRCPsych), is Deputy Director of the Medical Research Council Centre for Neuropsychiatric Genetics and Genomics at Cardiff University where he is also Professor of Psychiatric Genetics. He began his research career in 1989 as an MRC Training Fellow at Cardiff where, during his PhD (1989-1992), he developed novel methods for quantitating mRNA, and used these to show alterations in the relative expression of genes encoding subunits of GABAA receptors was a mechanism that contributes the biology of benzodiazepine tolerance. He was then an MRC Travelling Fellow at MIT (1992-93) based as a member of The Huntington’s Disease Collaborative Research Group, He has a broad interest in the molecular genetics and neurobiology of mental disorders and has held grants from major funding bodies for molecular genetic studies of schizophrenia, bipolar disorder, dyslexia, ADHD, and Alzheimer’s disease, and pharmacogenomics.
Prof O’Donovan co-chairs the Schizophrenia (SCZ) group of the Psychiatric Genomics Consortium (PGC).