The image is from their paper, “Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory, ” published in collaboration with Stephanie Gupton’s lab in the same edition.
UNC School of Medicine researchers have found a protein that appears to protect against coronary artery disease in older people with surprisingly clear arteries.
Dr. Bryan L. Roth, recipient of the ASPET 2016 Louis S. Goodman & Alfred Gilman Award in Receptor Pharmacology Our congratulations to Dr. Bryan L. Roth for being the recipient of the prestigious 2016 Louis S. Goodman & Alfred Gilman Award in Receptor Pharmacology by the American Society for Pharmacology and Experimental Therapeutics (ASPET). From … Read more
The Hahn, Kuhlman and Kasai labs developed a genetically encoded probe that can label and optically erase synapses that were enlarged or generated by motor learning. Dense labeling of synapses was found in a small subset of pyramidal neurons, and irradiation with blue light erased motor memory.
UNC and UCSF labs create a new research tool to find homes for two orphan cell-surface receptors, a crucial step toward finding better therapeutics and causes of drug side effects.
Scientists from the UNC / NC State joint biomedical engineering department are creating a new kind of research tool that will be nearly indistinguishable from the human gastrointestinal tract.
UNC Lineberger Comprehensive Cancer Center researchers and eight other leading cancer research institutions have won a five-year, $12 million grant to try to find treatments for a group of cancers linked to mutations in the NF1 gene.
Using a new ‘chemogenetic’ technique invented at UNC, scientists turn neurons ‘on’ and ‘off’ to demonstrate how brain circuits control behavior in mice. This unique tool – the first to result from the NIH BRAIN Initiative – will help scientists understand how to modulate neurons to more effectively treat diseases.
Dr. Mike Miley is co-PI, along with Dr. TinChung Leung of UNC State, on one of six three-year grants funded by the University of North Carolina General Administration to support game-changing faculty research in areas of strategic importance to the state.
Using human cancer cell lines, UNC scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.
