Jen Jen Yeh named Smithies Investigator

February 5, 2018

The UNC School of Medicine has selected Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, and joint professor of pharmacology, for one of two annual awards in honor of Oliver Smithies, UNC’s first Nobel Prize winner.

Scientific Breakthrough Could Lead to Better Antipsychotic Drugs

January 25, 2018

Published in Nature, research from the lab of Bryan L. Roth, MD, PhD, Distinguished Professor of Pharmacology, revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects to treat bipolar disorder, schizophrenia, and other conditions.

Scientists Take a Big Step toward Building a Better Opioid

January 11, 2018

In a paper published in Cell, research led by Bryan Roth, MD, PhD, and Roth lab members, Tao Ch, PhD and Daniel Wacker, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads to death – the most severe side effects of opioid use.

A microscope maker

December 7, 2017

Wesley Legant, PhD, Assistant Professor in Pharmacology, is highlighted in a Nature article on a do-it-yourself approach to microscopy that lead to the development of light sheet microscopy.

NIH renews grant funding the Bowles Alcohol Research Center

December 4, 2017

The center, established 20 years ago and led by Fulton Crews, PhD, Distinguished Professor in Pharmacology, will receive more than $8.7 million over five years to continue research on the effects of alcohol on the brain. Other pharmacology faculty who are PIs on the the grant are Clyde Hodge, PhD, Zoe McElligott, PhD, Tom Kash, PhD, Melissa Herman, PhD and Leslie Morrow, PhD.