Todd Cohen, PhD, and Jonathan Schisler, PhD

Todd Cohen, PhD, and Jonathan Schisler, PhD, will investigate the new ideas related to the regulation of the Tau protein, which plays a role in Alzheimer’s disease.

Todd Cohen, PhD, assistant professor of neurology, and Jonathan Schisler, PhD, assistant professor of pharmacology, were awarded a $3.1-million grant from the National Institute on Aging titled, “Dual CHIP Functions Control Tau Triage in Alzheimer’s Disease.”

The five-year project will combine the complimenting expertise of Cohen and Schisler, allowing them to study like never before key concepts related to the regulation of tau, a protein that accumulates and aggregates in patients with Alzheimer’s disease.  The overarching goal of the study is to provide a new framework to better understand and target pathological tau species to alleviate tau-mediated toxicity and neurodegeneration in patients with Alzheimer’s disease.

read the full article on UNC SOM News…