Skip to main content

Todd Cohen, PhD, and Jonathan Schisler, PhD

Todd Cohen, PhD, and Jonathan Schisler, PhD, will investigate the new ideas related to the regulation of the Tau protein, which plays a role in Alzheimer’s disease.

Todd Cohen, PhD, assistant professor of neurology, and Jonathan Schisler, PhD, assistant professor of pharmacology, were awarded a $3.1-million grant from the National Institute on Aging titled, “Dual CHIP Functions Control Tau Triage in Alzheimer’s Disease.”

The five-year project will combine the complimenting expertise of Cohen and Schisler, allowing them to study like never before key concepts related to the regulation of tau, a protein that accumulates and aggregates in patients with Alzheimer’s disease.  The overarching goal of the study is to provide a new framework to better understand and target pathological tau species to alleviate tau-mediated toxicity and neurodegeneration in patients with Alzheimer’s disease.

read the full article on UNC SOM News…