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Dr. Daugird successfully defended his PhD thesis, “Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment,” under the direction of Wes Legant on May 9th.”

Dr. Tim Daugird stands in his Pharmacology White Lab Coat with Dr. Wesley Legant after his PhD defense.


In Graduate Program

Shi Y, Daugird TA, Legant WR. A posterior approach to correct for focal plane offsets in lattice light sheet structured illumination microscopy. bioRxiv [Preprint]. 2024 Apr 26:2024.04.26.590138. doi: 10.1101/2024.04.26.590138. PMID: 38712141.
Daugird TA*, Shi Y,* Holland KL, Rostamian H, Liu Z, Lavis LD, Rodriguez J, Strahl BD, Legant WR. Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment. Nature Communications, 2024 May 16;15(1):4178. doi: 10.1038/s41467-024-48562-0. PMID: 38755200.
Holland KL*, Plutkis SE*, Daugird TA*, Sau A, Grimm JB, English BP, Zheng Q, Dave S, Rahman F, Xie L, Dong P, Tkachuk AN, Brown TA, Singer RH, Liu Z, Galbraith CG, Musser SM, Legant WR, Lavis LD. A series of spontaneously blinking dyes for super-resolution microscopy. bioRxiv [Preprint]. 2024 Feb 24:2024.02.23.581625. doi: 10.1101/2024.02.23.581625. PMID: 38766149.
Shi Y, Tabet JS, Milkie DE, Daugird TA, Yang CQ, Ritter AT, Giovannucci A, Legant WR. Smart Lattice Light Sheet Microscopy for imaging rare and complex cellular events. Nature Methods, 2024 Feb;21(2):301-310. doi: 10.1038/s41592-023-02126-0. Epub 2024 Jan 2. PMID: 38167656.
Shi Y, Daugird TA, Legant WR. A quantitative analysis of various patterns applied in lattice light sheet microscopy. Nature Communications, 2022 Aug 8;13(1):4607. doi: 10.1038/s41467-022-32341-w. PMID: 35941165.
Ahn JH, Davis ES, Daugird TA, Zhao S, Quiroga IY, Uryu H, Li J, Storey AJ, Tsai YH, Keeley DP, Mackintosh SG, Edmondson RD, Byrum SD, Cai L, Tackett AJ, Zheng D, Legant WR, Phanstiel DH, Wang GG. Phase separation drives aberrant chromatin looping and cancer developmentt. Nature. 2021 Jul;595(7868):591-595. doi: 10.1038/s41586-021-03662-5. Epub 2021 Jun 23. PMID: 34163069.

Before Graduate Program

Azoitei ML, Noh J, Marston DJ, Roudot P, Marshall CB, Daugird TA, Lisanza SL, Sandí MJ, Ikura M, Sondek J, Rottapel R, Hahn KM, Danuser G. Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways. J Cell Biol., 2019 Sep 2;218(9):3077-3097. doi: 10.1083/jcb.201812073. Epub 2019 Aug 16. PMID: 31420453; PMCID: PMC6719461.
* indicates co-first authorship

Pics from Tim’s celebration (click for larger view)

We wish you all the best, Tim!