
Dr. Brian Krumm of UNC-CH presents
April 8 @ 4:00 pm - 5:00 pm

Brian Krumm, PhD
Assistant Professor
Department of Pharmacology
University of North Carolina at Chapel Hill
Seminar title: “TBD”
Please join us and show support for our seminar speakers!
(For those unable to attend, a zoom link is available upon request to Mimi Baltz.)
Host: Henrik Dohlman
Dr. Krumm’s research is focused on understanding the integral membrane proteins, specifically the G Protein Coupled Receptor (GPCR). A member of the Roth lab, he helped to successfully facilitate the structural determination of multiple GPCRs including the first crystal structure of the active-state kappa opioid receptor in complex with state-distinct nanobody along with the crystal structure of the serotonin 5-HT2A GPCR and the Cryo-Em structure of this receptor and other GPCRs in complex with its cognate G-protein.
Most recently he was co-first author on this important paper published Dec. 26, 2024 in Cell, “Structure-guided design of a peripherally restricted chemogenetic system,” which describes the development of a groundbreaking molecular technology to reduce pain by targeting peripheral nervous system (PNS) nociceptors.