{"id":2425,"date":"2015-10-08T19:35:00","date_gmt":"2015-10-08T23:35:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/guanine-nucleotide-exchange-region-of-dbs-in-complex-with-cdc42\/"},"modified":"2018-10-09T11:25:03","modified_gmt":"2018-10-09T15:25:03","slug":"guanine-nucleotide-exchange-region-of-dbs-in-complex-with-cdc42","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/guanine-nucleotide-exchange-region-of-dbs-in-complex-with-cdc42\/","title":{"rendered":"Guanine nucleotide exchange region of Dbs in complex with Cdc42"},"content":{"rendered":"<div>\n<p style=\"text-align: left;\" align=\"center\"><strong>Author:<\/strong><br \/>\nKent Rossman<\/p>\n<p><strong>Reference:<\/strong><br \/>\nRossman KL, Worthylake DK, Snyder JT, Siderovski DP, Campbell SL, Sondek J: <strong>A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange<\/strong><br \/>\nEMBO J 2002 Mar 15;21(6):1315-26<\/p>\n<p>(PDB Code = <a href=\"http:\/\/www.rcsb.org\/pdb\/explore\/explore.do?structureId=1kz7\" target=\"_blank\" rel=\"noopener\">1KZ7<\/a>)<\/p>\n<p>Click on the images to see a larger version.<\/p>\n<p>View movie: <a title=\"\" href=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs_cdc42_rot-1-gif-movie.gif\" target=\"_blank\" rel=\"noopener\">GIF: 4MB<br \/>\n<\/a><\/p>\n<div style=\"width: 450px; text-align: center;\"><a href=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/kent1-1.gif\"><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"411\" class=\"image-inline somoverlay size-medium wp-image-2352\" style=\"width: 450px;\" title=\"kent1[1].gif\" src=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/kent1-1.gif\" alt=\"kent1[1].gif\" \/><\/a><br \/>\n<a href=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1.gif\"><img loading=\"lazy\" decoding=\"async\" width=\"256\" height=\"182\" class=\"somoverlay image-inline size-medium wp-image-2355\" style=\"width: 256px;\" title=\"dbs[1].gif\" src=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1.gif\" alt=\"dbs[1].gif\" srcset=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1.gif 803w, https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1-150x107.gif 150w, https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1-300x214.gif 300w, https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1-768x547.gif 768w, https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/dbs-1-719x512.gif 719w\" sizes=\"auto, (max-width: 256px) 100vw, 256px\" \/><\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Author: Kent Rossman Reference: Rossman KL, Worthylake DK, Snyder JT, Siderovski DP, Campbell SL, Sondek J: A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange EMBO J 2002 Mar 15;21(6):1315-26 (PDB Code = 1KZ7) Click on the images to see a larger version. View movie: GIF: 4MB<\/p>\n","protected":false},"author":22429,"featured_media":0,"parent":2404,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2425","page","type-page","status-publish","hentry","odd"],"acf":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages\/2425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/comments?post=2425"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages\/2425\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages\/2404"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/media?parent=2425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}