{"id":2427,"date":"2015-10-08T19:35:00","date_gmt":"2015-10-08T23:35:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/guanine-nucleotide-exchange-region-of-intersectin-in-complex-with-cdc42\/"},"modified":"2018-10-09T11:29:49","modified_gmt":"2018-10-09T15:29:49","slug":"guanine-nucleotide-exchange-region-of-intersectin-in-complex-with-cdc42","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/guanine-nucleotide-exchange-region-of-intersectin-in-complex-with-cdc42\/","title":{"rendered":"Guanine nucleotide exchange region of intersectin in complex with Cdc42"},"content":{"rendered":"<div>\n<p style=\"text-align: left;\" align=\"center\"><strong>Author:<\/strong><br \/>\nJason Snyder<\/p>\n<p><strong>Reference:<\/strong><br \/>\nSnyder JT, Worthylake DK, Rossman KL, Pruitt WM, Betts L, Siderovski DP, Der CJ, Sondek J: <strong>Structural basis for the selective activation of Rho GTPases by Dbl exchange factors<\/strong><br \/>\nNature Structural Biology 2002 Jun;9(6):468-75<\/p>\n<p>(PDB Code = <a href=\"http:\/\/www.rcsb.org\/pdb\/explore\/explore.do?structureId=1ki1\" target=\"_blank\" rel=\"noopener\">1KI1<\/a>)<\/p>\n<p>Click on the images to see a larger version.<\/p>\n<p>View movie: GIF: <a title=\"\" href=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/intercdc42-1-gif-movie.gif\" target=\"_blank\" rel=\"noopener\">3.7MB<\/a><\/p>\n<p><a href=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/intercdc1-1.gif\"><img decoding=\"async\" class=\"image-inline somoverlay size-medium wp-image-2375\" title=\"intercdc1[1].gif\" src=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-content\/uploads\/sites\/868\/2018\/10\/intercdc1-1.gif\" width=\"33%\" height=\"auto\" alt=\"intercdc1[1].gif\" \/><\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Author: Jason Snyder Reference: Snyder JT, Worthylake DK, Rossman KL, Pruitt WM, Betts L, Siderovski DP, Der CJ, Sondek J: Structural basis for the selective activation of Rho GTPases by Dbl exchange factors Nature Structural Biology 2002 Jun;9(6):468-75 (PDB Code = 1KI1) Click on the images to see a larger version. View movie: GIF: 3.7MB<\/p>\n","protected":false},"author":22429,"featured_media":0,"parent":2404,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2427","page","type-page","status-publish","hentry","odd"],"acf":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages\/2427","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/comments?post=2427"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages\/2427\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/pages\/2404"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/wp-json\/wp\/v2\/media?parent=2427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}