{"id":2431,"date":"2015-10-08T19:35:00","date_gmt":"2015-10-08T23:35:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/structure-of-autoinhibited-asef\/"},"modified":"2018-10-09T11:44:44","modified_gmt":"2018-10-09T15:44:44","slug":"structure-of-autoinhibited-asef","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/structure-of-autoinhibited-asef\/","title":{"rendered":"Structure of autoinhibited ASEF"},"content":{"rendered":"
\n

Author:<\/strong>
\nKent Rossman<\/p>\n

Reference:<\/strong>
\nMitin, N., Betts, L, Yohe, M.E., Der, C.J., Sondek, J., Rossman, K.L. Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression<\/strong>. Nat Struct Mol Biol. 2007 Sep;14(9):814-23.<\/p>\n

(PDB Code = 2PZ1<\/a>)<\/p>\n

Click on the images to see a larger version.<\/p>\n

View movie: MPG: 1.35 Mb<\/a><\/p>\n

\"asef_fig.jpg\"<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Author: Kent Rossman Reference: Mitin, N., Betts, L, Yohe, M.E., Der, C.J., Sondek, J., Rossman, K.L. Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression. Nat Struct Mol Biol. 2007 Sep;14(9):814-23. (PDB Code = 2PZ1) Click on the images to see a larger version. View movie: MPG: 1.35 Mb<\/p>\n","protected":false},"author":22429,"featured_media":0,"parent":2404,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2431","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"\nStructure of autoinhibited ASEF - Sondek Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/pharm\/sondeklab\/structure-gallery\/structure-of-autoinhibited-asef\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Structure of autoinhibited ASEF - Sondek Lab\" \/>\n<meta property=\"og:description\" content=\"Author: Kent Rossman Reference: Mitin, N., Betts, L, Yohe, M.E., Der, C.J., Sondek, J., Rossman, K.L. 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