Class schedules for the current semester are listed below.<\/p>\n
Please email\u00a0phcostudentservices@unc.edu<\/a>\u00a0to register for\u00a0all<\/u>\u00a0PHCO courses.<\/strong><\/p>\n Please note that for all classes:<\/strong>\u00a0The instructor, in consultation with UNC officials, will monitor classroom conditions and make appropriate instructional adjustments to support achieving course learning outcomes.<\/p>\n <\/p>\n (BIOC 667)<\/p>\n (2 cr hr) A combined lecture\/laboratory workshop for serious students of protein crystallography covering crystallization, x-ray diffraction data acquisition, and data handling.\u00a0Course intended primarily for graduate students. Students are recommended to pair this course with BIOC 669.<\/p>\n Permission of course director.<\/p>\n (BIOC 669)<\/p>\n (1 cr hr) Protein x-ray crystallography and cryo-electron microscopy are two of the principle techniques used to experimentally determine the structures of macromolecules. While the data collection and initial processing steps are quite different, the fields converge at the model building, refinement, and analysis stage. This course addresses the fundamental concepts and best practices of how to build, refine, and analyze macromolecular structures with an in-depth treatment of the software and methodologies. Students will solve and build protein structures from provided data, or if available, their own, and analyze the quality of the structures using current best-practices and gold-standard metrics.<\/p>\n (3 cr. hr) This graduate level course introduces students to the major areas of pharmacology and physiology and serves for a basis for advanced courses.\u00a0<\/span>Three lecture hours a week.<\/span><\/p>\n Registration is by permission of the instructor.\u00a0 This is a graduate-level course.<\/span><\/p>\n Who can enroll: Anyone (BBSP, Undergrad and Non-PHCO)<\/span><\/p>\n Requisites: Prerequisite, CHEM 430; permission of the instructor for students lacking the prerequisite.<\/a><\/p>\n (3 cr hr) This graduate-level course concentrates on up-to-date views of intercellular signal processing, with emphasis on signal transduction mechanisms as they relate to cellular\/physiological responses in both normal development and disease. Signaling mechanisms that will be discussed include autocrine, paracrine, juxtacrine signaling and cell-matrix interactions.<\/p>\n Any graduate student can enroll.<\/p>\n (1 cr hr) This graduate level course has been designed to help cultivate a variety of essential skills required to become successful in your scientific career. It is in part a journal club and a writing class. It is designed to provide preparation for the doctoral oral exam. This preparation includes learning to evaluate research designs and pharmacology literature.<\/p>\n<\/div>\n Students meet as a group with faculty members to develop skills in critical reading and to summarize and discuss selected aspects of current pharmacological literature. Fall and Spring<\/p>\n Open to Pharmacology students only.<\/p>\n (BIOC745)<\/p>\n (1 cr h r) This graduate-level course concentrates on up-to-date views of intercellular signal processing, with emphasis on signal transduction mechanisms as they relate to cellular\/physiological responses in both normal development and disease. Signaling mechanisms that will be discussed include autocrine, paracrine, juxtacrine signaling and cell-matrix interactions.<\/p>\n (GNET 749)<\/p>\n (2 cr hr) This graduate-level course concentrates on up-to-date views of intercellular signal processing, with emphasis on signal transduction mechanisms as they relate to cellular\/physiological responses in both normal development and disease. Signaling mechanisms that will be discussed include autocrine, paracrine, juxtacrine signaling and cell-matrix interactions.<\/p>\n There are\u00a0no<\/em>\u00a0formal prerequisites required for this\u00a0course\u00a0and\u00a0no<\/em>\u00a0prior experience with UNIX or the command line interface is expected.<\/p>\n<\/div>\n <\/p>\n *Email\u00a0phcostudentservices@unc.edu<\/a>\u00a0to register for all PHCO courses. Meeting times may change to accommodate schedules.<\/strong><\/p>\n Tuesdays, PHCO Dept Seminars, 4 p.m<\/a><\/p>\n Fridays, PHCO Student Research Seminars, 12 p.m.<\/a><\/p>\n Link to UNC Academic Calendar<\/a><\/p>\n Class Schedules \u2013 Fall 2025<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":" Class schedules for the current semester are listed below. Please email\u00a0phcostudentservices@unc.edu\u00a0to register for\u00a0all\u00a0PHCO courses. Please note that for all classes:\u00a0The instructor, in consultation with UNC officials, will monitor classroom conditions and make appropriate instructional adjustments to support achieving course learning outcomes. PHCO 667 – Macromolecular Crystallographic Methods* (BIOC 667) (2 cr hr) M\/F @ … Read more<\/a><\/p>\n","protected":false},"author":22429,"featured_media":0,"parent":2310,"menu_order":26,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-18561","page","type-page","status-publish","hentry","odd"],"acf":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/pages\/18561","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/comments?post=18561"}],"version-history":[{"count":13,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/pages\/18561\/revisions"}],"predecessor-version":[{"id":27631,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/pages\/18561\/revisions\/27631"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/pages\/2310"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media?parent=18561"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}PHCO 667 – Macromolecular Crystallographic Methods*<\/h2>\n
\nM\/F @ 1:25 – 3:15 PM (January 7 – February 27)<\/strong>
\nLocation: Medical School Wing-Rm 0124
\nCourse Instructor: Dr. Nate Nicely<\/p>\nPHCO 669 \u2013 Macromolecular Crystallographic Methods II*<\/h2>\n
\nM\/W @ 1:25 \u2013 3:20 PM (March 3 \u2013 April 7)<\/strong>
\nLocation: GMB 2007
\nCourse Instructor: Dr. Stuart Endo-Streeter<\/p>\nPHCO 702 \u2013 Principles of Pharmacology and Physiology*<\/h2>\n
\nM\/W\/F @ 9:05 \u2013 9:50 am (January 7 \u2013 May 7)<\/strong>
\nLocation: MEJ 3116
\nCourse Directors: Dr. Terry Kenakin<\/p>\nPHCO 728 – Neuropharmacology of Alcohol and Substance Use*<\/h2>\n
\nTuesday @ 9:20 – 11:15 am (January 13 – May 1)<\/strong>
\nLocation: MEJ 3103
\nCourse Instructor: Dr. Joyce Besheer<\/p>\nPHCO 730 \u2013 Seminar in Recent Advances in Pharmacology*<\/h2>\n
\nThursday @ 10:00 am \u2013 12:00 pm (January 7 \u2013 May 7)<\/strong>
\nLocation: MEJ 3106, GMB 4007, GMB 4095
\nCourse Instructor: Dr. Adam Palmer<\/p>\nPHCO 745 – Intracellular Signaling in Development and Disease*<\/h2>\n
\nT\/Th @ 2:00 – 3:15 PM (January 7 – February 11)<\/strong>
\nLocation: GMB 4007
\nCourse Instructors: Dr. Yuliya Pylayeva-Gupta and Dr. John Morris<\/p>\nPHCO 749 \u2013 Practical RNA-SEQ*<\/h2>\n
\nM\/W\/F 1:20 \u2013 2:50 pm ( March 25 \u2013 April 27)<\/strong>
\nLocation: Marsico 2004 (and occasionally MEJ 3116 – 3\/27, 4\/10, 4\/17, 4\/24)
\nCourse Instructors: Dr. Mauro Calabrese, Dr. Jesse Raab, and Dr. Tristan<\/span>\u00a0<\/span>De Buysscher<\/p>\n<\/div>\n