Class schedules for the current semester are listed below.<\/p>\n
Please email\u00a0phcostudentservices@unc.edu<\/a>\u00a0to register for\u00a0all<\/u>\u00a0PHCO courses.<\/strong><\/p>\n Please note that for all classes:<\/strong>\u00a0The instructor, in consultation with UNC officials, will monitor classroom conditions and make appropriate instructional adjustments to support achieving course learning outcomes.<\/p>\n (2 cr hr) Macromolecular Crystallographic Methods II builds upon the data collection and reduction techniques taught in Methods I. Students will use datasets, either from their own research or supplied by the instructor, to train on modern software and learn best-practices to build, refine, and assess protein crystal and cryo-EM structures. Classes will be a mixture of lectures, introducing concepts and techniques, and labs, translating the lectures into practice.<\/p>\n (3 cr. hr) This graduate level course introduces students to the major areas of pharmacology and physiology and serves for a basis for advanced courses.\u00a0<\/span>Three lecture hours a week.<\/span><\/p>\n Registration is by permission of the instructor.\u00a0 This is a graduate-level course.<\/span><\/p>\n Who can enroll: Anyone (BBSP, Undergrad and Non-PHCO)<\/span><\/p>\n Requisites: Prerequisite, CHEM 430; permission of the instructor for students lacking the prerequisite.<\/a><\/p>\n (1 cr. hr) This graduate level course has been designed to help cultivate a variety of essential skills required to become successful in your scientific career. It is in part a journal club and a writing class. It is designed to provide preparation for the doctoral oral exam. This preparation includes learning to evaluate research designs and pharmacology literature.<\/p>\n<\/div>\n Students meet as a group with faculty members to develop skills in critical reading and to summarize and discuss selected aspects of current pharmacological literature. Fall and Spring<\/p>\n Open to Pharmacology students only.<\/p>\n ( 1 cr hr) This graduate-level course is an in-depth analysis of how protein kinases and protein phosphorylation regulates key aspects of cell signaling. This class is one of the \u201cContemporary Topics in Cell Signaling\u201d modules.<\/p>\n Permission of the instructor. Required preparation, coursework in biochemistry, pharmacology and\/or cell & molecular biology.<\/p>\n (1 cr hr) This graduate-level course conveys principles of signal transduction controlled by GTPases and emphasizes in-depth discussion of current literature and unanswered questions. This class is one of the \u201cContemporary Topics in Cell Signaling\u201d modules.<\/p>\n Permission of the instructor. Required preparation, coursework in biochemistry, pharmacology, and\/or cell & molecular biology.<\/p>\n (1 cr hr) This graduate-level course conveys principles of eukaryotic cell proliferation control emphasizing in-depth discussion of current literature and unanswered questions. This class is one of the Contemporary Topics in Cell Signaling modules.<\/p>\n Permission of the instructor. Required preparation, coursework in biochemistry and\/or cell & molecular biology.<\/p>\n (2 cr hr) This graduate-level course concentrates on up-to-date views of intercellular signal processing, with emphasis on signal transduction mechanisms as they relate to cellular\/physiological responses in both normal development and disease. Signaling mechanisms that will be discussed include autocrine, paracrine, juxtacrine signaling and cell-matrix interactions.<\/p>\n There are\u00a0no<\/em>\u00a0formal prerequisites required for this\u00a0course\u00a0and\u00a0no<\/em>\u00a0prior experience with UNIX or the command line interface is expected.<\/p>\n<\/div>\n<\/div>\n<\/div>\n (1 cr hr) This course will familiarize graduate students with the fundamental concepts of mass spectrometry-based proteomics with emphasis on its applications (expression proteomics, post-translational modification identification, and interactomics) and practical aspects of these applications, such as experimental design, sample preparation and data interpretation. This course is intended for 2nd year students and above who currently use or plan to use proteomics in their research.<\/p>\n Enrollment cap of 30<\/p>\n<\/div>\n<\/div>\n<\/div>\n <\/p>\nPHCO\/BIOC 669 \u2013 Macromolecular Crystallographic Methods II*<\/h2>\n
\nM\/W @ 1:25 \u2013 3:20 PM (March 3 – April 7)<\/strong>
\nLocation: Genetic Medicine Re-Rm 2007
\nCourse Instructor: De. Stuart Endo-Streeter<\/p>\nPHCO 702 \u2013 Principles of Pharmacology and Physiology*<\/h2>\n
\nM\/W\/F @ 9:05 \u2013 9:50 am (January 8 – May 9)<\/strong>
\nLocation: TBA
\nCourse Director: Dr. Terry Kenakin<\/p>\nPHCO 730 \u2013 Seminar in Recent Advances in Pharmacology*<\/h2>\n
\nThursday @ 10:00 am \u2013 12:00 pm (January 8 – May 9)<\/strong>
\nLocation: MEJ 3112 (waiting for 2 more classrooms)
\nCourse Instructor: Dr. Adam Palmer<\/p>\nPHCO\/BIOC 740 \u2013 Contemporary Topics in Cell Signaling: Phosphorylation Control & Protein Kinases*<\/h2>\n<\/div>\n<\/div>\n<\/div>\n
\nT\/Th @ 2:00 \u2013 3:30 pm (January 14 \u2013 February 11)<\/strong>
\nLocation: TBA
\nCourse Instructor: Dr. Lee Graves<\/p>\nPHCO\/BIOC 741\u2013 Contemporary Topics in Cell Signaling: GTPases*<\/h2>\n
\nT\/Th @ 2:00 \u2013 3:30 pm (February 13 \u2013 March 24)<\/strong>
\nLocation: Marsico Hall-Rm 5004
\nCourse Instructor: Dr. Kirsten Bryant<\/p>\nPHCO\/BIOC 742 \u2013 Contemporary Topics in Cell Signaling: Cell Cycle Control*<\/h2>\n
\nT\/Th @ 2:00 \u2013 3:30 pm (March 25 \u2013 May 1)<\/strong>
\nLocation: TBA
\nCourse Instructor: Dr. Mike Emanuele<\/p>\nPHCO\/GNET749 \u2013 Practical RNA-SEQ*<\/h2>\n
\nM\/W\/F 1:20 \u2013 2:50 pm ( January 8 \u2013 May 9)<\/strong>
\nLocation: TBA
\nCourse Instructors: Drs. Mauro Calabrese, Jesse Raab, Tristan<\/span>\u00a0<\/span>De Buysscher<\/p>\n<\/div>\nPHCO 750 \u2013 Proteomics Methods and Applications<\/h2>\n
\nM\/W 1:30 \u2013 300 pm (Januray 29 \u2013 March 5)<\/strong>
\nLocation: MEJ 3108
\nCourse Instructor: Dr. Laura Herring<\/p>\n