Class schedules for the current semester are listed below.<\/p>\n
Please email\u00a0phcostudentservices@unc.edu<\/a>\u00a0to register for\u00a0all<\/u>\u00a0PHCO courses.<\/strong><\/p>\n Please note that for all classes:<\/strong>\u00a0The instructor, in consultation with UNC officials, will monitor classroom conditions and make appropriate instructional adjustments to support achieving course learning outcomes.<\/p>\n (3 cr. hr) Course Description:<\/strong>\u00a0This is a graduate-level first year course outlining the basics of molecular pharmacology, including molecular biology, bioinformatics, drug\/receptor interactions, receptor and ion channels, regulation of second messengers, drug metabolism and system pharmacology.<\/p>\n Permission of the instructor required for registration.<\/strong><\/p>\n Course Description:<\/strong> The objectives of this course are to provide graduate students in biomedical research programs familiarity with the molecular principles of pharmacology involved in the design and action of drugs. Students will increase critical thinking skills in the context of the specific topics listed in the syllabus, which includes molecular biology underlying drug development, key drugable pathways and the interactions between drugs and human body. By the end of this course students should be familiar with molecular principles of drug development including knowledge of gene expression pathways related to drugs, key drugable targets and the interaction between drugs and their receptors. Students should have working knowledge sufficient to apply those principles to new research topics and to propose appropriate strategies to solve relevant research questions.<\/p>\n (2 cr. hr) Course Description:<\/strong>\u00a0One of the most important skills you will develop in graduate school, regardless of your future career, is the ability to communicate. The skills needed to communicate effectively cut across different mediums, and include subject matter knowledge, describing complex topics clearly, crafting arguments, and knowing your audience. The primary goal of this class is to help you develop those skills. Along the way, we will also further develop critical thinking as it relates to addressing a scientific question.<\/p>\n Prerequisite,\u00a0PHCO\u00a0701<\/a>; Permission of the instructor for students lacking the prerequisite.<\/span><\/strong><\/p>\n<\/div>\n MWF @ 10:00 am \u2013 10:50 am\u00a0<\/strong> Course Description:<\/strong>\u00a0Drug Discovery and Development, now done in both industrial and academic settings,\u00a0 is critical to patient healthcare.\u00a0 Pharmacology is an essential element in Drug Discovery process and this elective will familiarize registrants with the various elements involved in the research of finding new drugs. The course spans the complete range of activities from bioinformatic choice of drug targets, validation of drug targets, demonstration of target engagement, screening for new molecules, lead optimization, biologist\/chemist interface structure activity study, and clinical testing of drug candidates. All of these endeavors are common to discovery irrespective of the pathology being prosecuted and examples will be presented from CNS, cardiovascular, inflammation, cancer disease areas. In addition, biologics will be discussed as well as conventional small molecule drugs. In general, registrants should emerge from this course with an idea of what drug discovery involves and whether or not they might be interested in this type of research.<\/p>\n Course Content<\/i><\/b><\/p>\n Discovery in an Industrial Setting and Academia \/ Project Initiation\u00a0 \/ \u2018Drugging\u2019 Targets\u00a0 \/ Confirming Target Engagement \/ Target Manipulation for Therapies \/ Lead Optimization \/ candidate characterization \/ The World of Biologics \/ Development of Drug Candidates: Pharmacokinetics\u00a0 \/ Development of Drug Candidates: Early Safety \/ Clinical Testing of Candidates<\/i><\/p>\n<\/div>\n<\/div>\n<\/div>\n <\/p>\n *Email\u00a0phcostudentservices@unc.edu<\/a>\u00a0to register for all PHCO courses. Meeting times may change to accommodate schedules.<\/strong><\/p>\n Tuesdays, PHCO Dept Seminars, 4 p.m<\/a><\/p>\n Fridays, PHCO Student Research Seminars, 12 p.m.<\/a><\/p>\n Link to Quantitative Skills Resources<\/a><\/p>\n Link to UNC Academic Calendar<\/a><\/p>\nPHCO 701 \u2013 Introduction to Molecular Pharmacology*<\/h2>\n
\nM\/W\/F @ 9:05 am \u2013 9:50 am\u00a0<\/strong>
\nLocation:<\/strong>\u00a0MEJ 3116
\nCourse Director:<\/strong>\u00a0Dr. Terry Kenakin<\/p>\nPHCO 732 – Fellowship\/Grant Writing*<\/span><\/h2>\n
\nThis course is only open to Pharmacology students.<\/strong>
\nTuesday @ 1:00 pm \u2013 3:00 pm<\/strong>
\nLocation:<\/strong>\u00a0MEJ 3104, 3106 and 3108
\nCourse Instructor:<\/strong>\u00a0Dr. Melissa Herman<\/p>\nPHCO 733 \u2013 Drug Discovery and Development*<\/h2>\n<\/div>\n<\/div>\n
\nLocation:<\/strong>\u00a0MEJ 3102
\nCourse Instructor:<\/strong>\u00a0Dr. Terry Kenakin<\/p>\n