{"id":24793,"date":"2025-03-11T16:32:13","date_gmt":"2025-03-11T20:32:13","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/?p=24793"},"modified":"2025-04-30T14:09:36","modified_gmt":"2025-04-30T18:09:36","slug":"leon-coleman-receives-2025-aspet-early-career-award","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/pharm\/leon-coleman-receives-2025-aspet-early-career-award\/","title":{"rendered":"Leon Coleman Receives 2025 ASPET Early Career Award!"},"content":{"rendered":"<p class=\"lead\">Congratulations to Dr. <b>Leon Coleman <\/b>for receiving the prestigious 2025 ASPET Division for Neuropharmacology Early Career Award!<\/p>\n<figure id=\"attachment_24794\" class=\"thumbnail wp-caption alignnone\" style=\"width: 260px\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-24794\" src=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/03\/lcoleman_neu_200x230.png\" alt=\"Leon Coleman, MD PhD\" width=\"250\" height=\"288\" \/><figcaption class=\"caption wp-caption-text\">Leon Coleman, MD, PhD<\/figcaption><\/figure>\n<p>Dr. Coleman is receiving this award in recognition of his research, teaching and lasting contributions to pharmacology.<\/p>\n<p><strong>From the ASPET Award website:\u00a0<\/strong>&#8220;Dr. Coleman has a history of making pioneering discoveries in the field of neuropharmacology, particularly Alcohol Use Disorder (AUD) and Alzheimer\u2019s disease (AD) research. Recently, he has focused on finding novel regulators of immune pathology for alcohol abuse, Alzheimer&#8217;s disease, and severe burn injury. Dr. Coleman has found that heavy alcohol use promotes Alzheimer\u2019s pathology through persistent activation of microglia leading to the disruption of neuronal lipid metabolism. He identified the loss of neuronal lysosomal acid lipase as a fundamental feature of the progression of Alzheimer\u2019s disease that is enhanced by heavy alcohol use and midlife obesity. This has resulted in a US patent, and the development of novel PET ligands for the early diagnosis of Alzheimer\u2019s disease. His work has identified extracellular vesicles are fundamental drivers of immune dysfunction in AUD and burn injury. The targeted removal of these detrimental vesicles is now under investigation as a novel immunotherapy approach.&#8221;<\/p>\n<p>&#8220;The award will be presented by the Division for Neuropharmacology on April 5, 2025, during the ASPET 2025 Annual Meeting in Portland, Ore. Additionally, Dr. Coleman has been invited to give a lecture on his work as part of the annual meeting.<\/p>\n<p>~the above two quotes are excerpts from the <a href=\"https:\/\/www.aspet.org\/aspet\/meetings-awards\/aspet-awards\/aspet-scientific-achievement-awards\/aspet-award-winners\/2025-award-winners#woods\">2025 ASPET Award website.<\/a><\/p>\n<div class=\"elementToProof\"><\/div>\n<div class=\"elementToProof\"><u><a id=\"OWAe76d7396-dc6d-5187-0b53-cccb440d8f1b\" class=\"OWAAutoLink\" title=\"https:\/\/www.aspet.org\/aspet\/meetings-awards\/aspet-awards\/aspet-scientific-achievement-awards\/aspet-award-winners\/2025-award-winners#woods\" href=\"https:\/\/www.aspet.org\/aspet\/meetings-awards\/aspet-awards\/aspet-scientific-achievement-awards\/aspet-award-winners\/2025-award-winners#woods\" data-linkindex=\"2\" data-auth=\"NotApplicable\">Click here<\/a><\/u>\u00a0for 2025 ASPET Award Winners!<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to Dr. Leon Coleman for receiving the prestigious 2025 ASPET Division for Neuropharmacology Early Career Award!<\/p>\n","protected":false},"author":22429,"featured_media":24796,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[18,2],"tags":[],"class_list":["post-24793","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty-news","category-news","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/03\/leon_coleman_250_2.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/03\/leon_coleman_250_2.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/03\/leon_coleman_250_2.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/03\/leon_coleman_250_2.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/03\/leon_coleman_250_2-150x150.jpg","featured_image_alt":"Leon Coleman, MD PhD","category_details":[{"name":"Faculty News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/faculty-news\/"},{"name":"News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/24793","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/comments?post=24793"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/24793\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media\/24796"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media?parent=24793"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/categories?post=24793"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/tags?post=24793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}