{"id":25191,"date":"2025-06-03T14:00:28","date_gmt":"2025-06-03T18:00:28","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/?p=25191"},"modified":"2025-08-12T12:40:59","modified_gmt":"2025-08-12T16:40:59","slug":"congratulations-to-our-new-phd-adam-graves","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/pharm\/congratulations-to-our-new-phd-adam-graves\/","title":{"rendered":"Congratulations to our new PhD, Adam Graves!"},"content":{"rendered":"

Dr. Graves successfully defended his PhD thesis, “ERK Regulates IKK Epsilon Expression and Oncogenic Functions of Pancreatic Cancer” under the guidance of Dr. Albert Baldwin.<\/p>\n

\"Adam<\/a><\/p>\n

Publications<\/h2>\n

AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms.\u00a0<\/a> Castillo Cabrera J, Dang H,\u00a0Graves\u00a0A,<\/strong>\u00a0Zhang Z, Torres-Castillo J, Li K, King Z, Liu P, Aub\u00e9 J, Bear JE, Damania B, Hagan RS, Baldwin AS. Cell Chem Biol. 2023 Dec 21;30(12):1601-1616.e6. doi: 10.1016\/j.chembiol.2023.10.008. Epub 2023 Nov 7. PMID:\u00a037939709. PMC10842197 <\/a><\/p>\n

Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues.\u00a0<\/a> Graves\u00a0PR, Aponte-Collazo LJ, Fennell EMJ,\u00a0Graves\u00a0AC<\/strong>, Hale AE, Dicheva N, Herring LE, Gilbert TSK, East MP, McDonald IM, Lockett MR, Ashamalla H, Moorman NJ, Karanewsky DS, Iwanowicz EJ, Holmuhamedov E,\u00a0Graves\u00a0LM. ACS Chem Biol. 2019 May 17;14(5):1020-1029. doi: 10.1021\/acschembio.9b00222. Epub 2019 May 1. PMID:\u00a031021596. PMC6528275 <\/a><\/p>\n

Dr. Graves is also a first author on a paper that has been submitted and is in revision with the Journal of Biological Chemistry. UPDATE:<\/span><\/strong> this paper has been accepted and is in press! Epub: July 28, 2025.<\/em><\/p>\n

ERK signaling promotes IKK\u03b5 expression and oncogenic functions in pancreatic cancer cells in association with TBK1. Adam Graves,<\/strong> Angana Mukherjee, Runying Yang, Angie Mordant, Thomas Webb, Kirsten Bryant, Laura Herring, Albert Baldwin. Journal of Biological Chemistry. 2025 July 28; doi: 10.1016\/j.jbc.2025.110535<\/a>. In press, Epub: July 28, 2025.<\/p>\n

Honors, Awards & Highlights<\/h2>\n

Pharmacology Service and Outreach Award, 2023<\/a><\/p>\n

UNC BBSP First Year Group Peer Mentor Advisor (Fall 2024)<\/p>\n

UNC BBSP First Year Group Lead Peer Mentor (Fall 2023 \u2013 Spring 2024)<\/p>\n

UNC BBSP First Year Group Peer Mentor (Fall 2020 \u2013 Spring 2023)<\/p>\n

Pharmacology Carolina Summer Fellows Program Ambassador, 2021, 2022, 2023, 2024<\/a><\/p>\n

Pharmacology Carolina Summer Fellow Program Alumni, 2017<\/a><\/p>\n

 <\/p>\n

\"Adam<\/a>
Adam defending his PhD thesis<\/div><\/div>
\"Mauro<\/a>
Adam’s PHCO White Coat Ceremony!<\/div><\/div>
\"Adam's<\/a>
Mauro shows off the front of his PHCO lab coat.<\/div><\/div>
\"Mauro<\/a>
and the back<\/div><\/div><\/div>
\"Mauro<\/a>
and hands it to Adam<\/div><\/div>
\"Congratulations<\/a>
He’s got it now! Congratulations, Adam!<\/div><\/div>
\"Adam<\/a>
Adam receiving the Pharmacology Service and Outreach Award, Dec. 2023!<\/div><\/div>
\"Our<\/a>
After an awesome CSF presentation (back row, 1st left)! <\/div><\/div><\/div>
\"\"<\/a>
As a new CSF student!<\/div><\/div>
\"Ghostbusters<\/a>
As a ghostbuster! (Adam is 2nd from right)<\/div><\/div>
\"CSF<\/a>
As CSF Ambassador (back row, 1st from right)<\/div><\/div><\/div><\/div>\n

Congratulations, Adam, we wish you all the best!<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Dr. Graves successfully defended his PhD thesis, “ERK Regulates IKK Epsilon Expression and Oncogenic Functions of Pancreatic Cancer” under the guidance of Dr. Albert Baldwin.<\/p>\n","protected":false},"author":22429,"featured_media":25241,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,19],"tags":[],"class_list":["post-25191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-student-postdoc-news","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/06\/Adam-Garves-closeup-phd-defense-250.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/06\/Adam-Garves-closeup-phd-defense-250.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/06\/Adam-Garves-closeup-phd-defense-250.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/06\/Adam-Garves-closeup-phd-defense-250.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/06\/Adam-Garves-closeup-phd-defense-250-150x150.jpg","featured_image_alt":"Adam Graves at his PhD Defense","category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/"},{"name":"Student & Postdoc News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/student-postdoc-news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/25191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/comments?post=25191"}],"version-history":[{"count":26,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/25191\/revisions"}],"predecessor-version":[{"id":25807,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/25191\/revisions\/25807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media\/25241"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media?parent=25191"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/categories?post=25191"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/tags?post=25191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}