{"id":27107,"date":"2025-11-07T16:25:18","date_gmt":"2025-11-07T21:25:18","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/?p=27107"},"modified":"2026-01-07T10:40:06","modified_gmt":"2026-01-07T15:40:06","slug":"congratulations-to-our-new-phd-gabriella-gentile","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/pharm\/congratulations-to-our-new-phd-gabriella-gentile\/","title":{"rendered":"Congratulations to our new PhD, Gabriella Gentile!"},"content":{"rendered":"

Dr. Gentile successfully defended her PhD thesis, “Impact of the L421P Mutation in Penicillin-Binding Protein 1 on Fitness and Antibiotic Resistance in Neisseria Gonorrhoeae,”<\/em> under the guidance of her mentor, Dr. Rob Nicholas.<\/p>\n

\"Gabi<\/a><\/p>\n

Publications<\/h2>\n

Gentile, G.,<\/b> Guzman, B., Le Van, A., Jerse, A. E., Grad, Y. H., Dominguez, D., Mortimer, T. D., & Nicholas, R. A. (2025). The role of the L421P mutation in Penicillin-Binding Protein 1 (PBP1) in the evolution of chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. bioRxiv. https:\/\/doi.org\/10.1101\/2025.06.27.662027<\/span><\/a>.<\/span><\/p>\n

Helekal, D., Mortimer, T. D., Mukherjee, A., Gentile, G., <\/b>Le Van, A., Nicholas, R. A., Jerse, A. E., Palace, S. G., & Grad, Y. H. (2025). Quantifying the impact of antibiotic use and genetic determinants of resistance on bacterial lineage dynamics. bioRxiv. https:\/\/doi.org\/10.1101\/2025.02.03.636319<\/span><\/a>.<\/span><\/p>\n

Dr. Gentile has a paper under review at mBio and another paper that was recently accepted at Nature Microbiology.<\/em><\/p>\n

Honors, Awards & Highlights<\/h2>\n

Dr. Gentile was funded by the following T32 training grants while working in Rob Nicholas\u2019 lab<\/p>\n

Training in Sexually Transmitted Diseases and HIV T32<\/span><\/p>\n

Pharmacological Science Training Program (PSTP) T32\u00a0<\/span><\/p>\n

\"Gabi<\/a>
Gabi at the podium for her PhD defense<\/div><\/div>
\"Gabi<\/a>
Rob Nicholas and Gabi<\/div><\/div>
\"Gabi<\/a>
Congratulations, Gabi!<\/div><\/div>
\"Henrik<\/a>
Gabi and Henrik at her Pharmacology white lab coat ceremony<\/div><\/div><\/div>
\"Henrik<\/a>
Henrik presents Gabi with her pharmacology white lab coat<\/div><\/div>
\"Gabi<\/a>
Gabi holding her Pharmacology white lab coat<\/div><\/div>
\"Gabi<\/a>
Gabi holds up her Pharmacology white lab coat up<\/div><\/div><\/div><\/div>\n

Congratulations, Gabi, we wish you all the best!<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Dr. Gentile successfully defended her thesis, “Impact of the L421P Mutation in Penicillin-Binding Protein 1 on Fitness and Antibiotic Resistance in Neisseria Gonorrhoeae” under the guidance of her mentor, Rob Nicholas.<\/p>\n","protected":false},"author":22429,"featured_media":27113,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,19],"tags":[],"class_list":["post-27107","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-student-postdoc-news","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/11\/GabiGentile-250.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/11\/GabiGentile-250.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/11\/GabiGentile-250.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/11\/GabiGentile-250.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2025\/11\/GabiGentile-250-150x150.jpg","featured_image_alt":"Gabi Gentile, PhD","category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/"},{"name":"Student & Postdoc News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/student-postdoc-news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/27107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/comments?post=27107"}],"version-history":[{"count":14,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/27107\/revisions"}],"predecessor-version":[{"id":27133,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/27107\/revisions\/27133"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media\/27113"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media?parent=27107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/categories?post=27107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/tags?post=27107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}