{"id":28047,"date":"2026-05-27T12:44:52","date_gmt":"2026-05-27T16:44:52","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/?p=28047"},"modified":"2026-05-27T12:58:58","modified_gmt":"2026-05-27T16:58:58","slug":"dr-channing-der-and-dr-jen-jen-yehs-work-on-ras-highlighted-in-the-new-england-journal-of-medicine","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/pharm\/dr-channing-der-and-dr-jen-jen-yehs-work-on-ras-highlighted-in-the-new-england-journal-of-medicine\/","title":{"rendered":"Dr. Channing Der and Dr. Jen Jen Yeh&#8217;s work on RAS highlighted in the New England Journal of Medicine. \u201c"},"content":{"rendered":"<p class=\"lead\">Congratulations to Dr. <b>Channing Der<\/b> Dr. <b>Jen Jen Yeh<\/b>\u00a0on the publication of their recent article, <i>\u201cAdvances in RAS Therapeutics for Pancreatic Cancer.\u201d<\/i><\/p>\n<div style=\"width: 100%;clear: left\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-15773\" src=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2021\/03\/channing-der-250-2.jpg\" alt=\"Channing Der, PhD\" width=\"250\" height=\"250\" srcset=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2021\/03\/channing-der-250-2.jpg 250w, https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2021\/03\/channing-der-250-2-150x150.jpg 150w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19368\" src=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2022\/09\/Jen-Jen-Yeh-Vertical-250.jpg\" alt=\"Jen Jen Yeh, MD\" width=\"250\" height=\"250\" srcset=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2022\/09\/Jen-Jen-Yeh-Vertical-250.jpg 250w, https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2022\/09\/Jen-Jen-Yeh-Vertical-250-150x150.jpg 150w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/><\/p>\n<div style=\"width: 100%;clear: left\"><em>Channing Der, PhD (L) and Jen Jen Yeh, MD (R)<\/em><\/div>\n<p>Their work highlights emerging treatments targeting KRAS mutations which are found in the vast majority of pancreatic cancers and discusses the promising early clinical results of daraxonrasib, a novel drug designed to target RAS-driven tumors. This research represents an exciting step forward in the development of new treatment options for pancreatic cancer patients.<\/p>\n<p class=\"p1\"><a href=\"https:\/\/www.newsbreak.com\/medpage-today-359398486\/4635869722159-safety-data-on-the-novel-pancreatic-cancer-drug-available-by-early-access\"><span class=\"s1\">Read the article,<em> &#8220;<\/em><\/span><em>Safety Data on the Novel Pancreatic Cancer Drug Available by Early Access,&#8221;<\/em> published in NewsBreak!<\/a><\/p>\n<p>Read the UNC School of Medicine Lineberger Comprehensive Cancer Center article highlighting their work, <em><a href=\"https:\/\/unclineberger.org\/news\/der-yeh-scientific-context-recent-ras-therapeutics-for-pancreatic-cancer\/\">&#8220;Der, Yeh provide scientific context for recent progress in RAS therapeutics for pancreatic cancer.&#8221;<\/a><\/em><\/p>\n<p>Read their published article, <a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMe2600517\"><span class=\"s2\"><i>\u201cAdvances in RAS Therapeutics for Pancreatic Cancer,\u201d<\/i><\/span><\/a><span class=\"s1\"> in the New England Journal of Medicine <em>(accessible with a free account or by subscription only).<\/em><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations on the publication of their recent article, &#8220;Advances in RAS Therapeutics for Pancreatic Cancer.\u201d\u00a0<\/p>\n","protected":false},"author":22429,"featured_media":28091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[18,11,2],"tags":[],"class_list":["post-28047","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty-news","category-featured","category-news","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2026\/05\/der-yeh-250.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2026\/05\/der-yeh-250.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2026\/05\/der-yeh-250.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2026\/05\/der-yeh-250.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2026\/05\/der-yeh-250-150x150.jpg","featured_image_alt":"Channing Der, PhD and Jen Jen Yeh, MD","category_details":[{"name":"Faculty News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/faculty-news\/"},{"name":"Featured News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/featured\/"},{"name":"News","link":"https:\/\/www.med.unc.edu\/pharm\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/28047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/comments?post=28047"}],"version-history":[{"count":13,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/28047\/revisions"}],"predecessor-version":[{"id":28090,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/posts\/28047\/revisions\/28090"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media\/28091"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media?parent=28047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/categories?post=28047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/tags?post=28047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}