{"id":10918,"date":"2025-07-17T13:56:51","date_gmt":"2025-07-17T17:56:51","guid":{"rendered":"https:\/\/www.med.unc.edu\/phyrehab\/?p=10918"},"modified":"2025-07-17T14:39:52","modified_gmt":"2025-07-17T18:39:52","slug":"new-research-finds-changing-your-diet-could-ease-persistent-headaches-after-brain-injury","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/phyrehab\/uncategorized\/new-research-finds-changing-your-diet-could-ease-persistent-headaches-after-brain-injury\/","title":{"rendered":"New Research Finds Changing Your Diet Could Ease Persistent Headaches After Brain Injury"},"content":{"rendered":"<p><em>A new study, led by investigators in the Department of Physical Medicine &amp; Rehabilitation at the UNC School of Medicine, reveals how dietary changes significantly reduce persistent post-traumatic headaches, a common and debilitating consequence of traumatic brain injury. Link to <a href=\"https:\/\/news.unchealthcare.org\/2025\/07\/changing-your-diet-could-ease-persistent-headaches-after-brain-injury-study-shows\/\" target=\"_blank\" rel=\"noopener\">original article<\/a>.<\/em><\/p>\n<p>&nbsp;<\/p>\n<p>CHAPEL HILL, NC \u2013 A new clinical trial demonstrates that dietary changes significantly reduce persistent post-traumatic headaches (pPTH), a common and debilitating consequence of traumatic brain injury (TBI). Researchers from the UNC School of Medicine, the Uniformed Services University, and the National Institutes of Health (NIH) found that increasing omega-3 fatty acids (commonly found in fatty fish like salmon and tuna) while reducing omega-6 fatty acids (abundant in seed oils such as corn, sunflower, and cottonseed oils) led to fewer and less severe headaches.<\/p>\n<p>Published in the\u00a0<a href=\"https:\/\/www.liebertpub.com\/doi\/abs\/10.1089\/neu.2025.0126\"><em>Journal of Neurotrauma<\/em><\/a>, the randomized trial involved 122 military health care beneficiaries suffering from chronic headaches following TBI. In addition to their current headache treatments, patients were asked to adhere to one of two diets for 12 weeks: a control diet with average US amounts of omega-3 and omega-6 fatty acids, or an intervention diet that increased omega-3 and decreased omega-6 fatty acids. Participants were provided with most of their daily food intake for the duration of the trial. The trial was conducted at three sites: Walter Reed National Military Medical Center in Maryland, Alexander T. Augusta Military Medical Center in Virginia, and Womack Army Medical Center in North Carolina.<\/p>\n<figure id=\"attachment_39440\" class=\"thumbnail wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-39440\" src=\"https:\/\/news.unchealthcare.org\/wp-content\/uploads\/sites\/1159\/2025\/07\/00100lPORTRAIT_00100_BURST20200719182918772_COVER-1-225x300.jpg\" alt=\"salmon\" width=\"225\" height=\"300\" \/><figcaption class=\"caption wp-caption-text\">photo credit: Beth MacIntosh, RD<\/figcaption><\/figure>\n<p>Participants assigned to the intervention diet experienced approximately two fewer headache days per month and a 30% reduction in daily headache pain intensity compared to the control diet group. Blood analyses confirmed that the diet increased levels of anti-inflammatory and pain-reducing omega-3 derivatives.<\/p>\n<p>\u201cThis study is particularly exciting because it suggests that dietary interventions can stabilize neuroinflammatory processes triggered by brain injury,\u201d said Daisy Zamora, PhD, lead author and associate professor in the UNC Department of Physical Medicine &amp; Rehabilitation. \u201cBy changing the amounts of omega-3 and omega-6 fatty acids from those typical in modern industrialized diets to levels consistent with pre-industrial diets, this research can help us understand how the body naturally regulates pain. This knowledge is essential to the development of new and improved approaches for managing pain and inflammation in many disease conditions.\u201d<\/p>\n<figure id=\"attachment_39442\" class=\"thumbnail wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-39442\" src=\"https:\/\/news.unchealthcare.org\/wp-content\/uploads\/sites\/1159\/2025\/07\/00100lPORTRAIT_00100_BURST20200719175322513_COVER-1-225x300.jpg\" alt=\"healthy food\" width=\"225\" height=\"300\" \/><figcaption class=\"caption wp-caption-text\">photo credit: Beth MacIntosh, RD<\/figcaption><\/figure>\n<p>Persistent post-traumatic headaches affect more than 40% of individuals after TBI, including many military service members. Despite its prevalence, there are currently no FDA-approved treatments for pPTH. These findings suggest that targeted dietary strategies may offer a safe and accessible way to manage pain, and might even improve the results of traditional pain treatments when used together.<\/p>\n<p>\u201cThis research provides a compelling case for considering dietary adjustments as an adjunctive treatment option,\u201d said lead investigator, Kimbra Kenney, MD, professor, Department of Neurology, Uniformed Services University of the Health Sciences. \u201cThis is especially important for populations like military personnel, who are disproportionately affected by TBI-related chronic headaches.\u201d<\/p>\n<p><em>This work was supported by the U.S Army Medical Research and Materiel Command through the Congressionally Directed Medical Research Programs for the Department of Defense through the Henry Jackson Foundation for the Advancement of Military Medicine (Award number W81XwH-15-2-0059)<\/em><em>\u00a0and included contributions from the National Institutes of Health Intramural Research Program (project number ZIAAG000453). Clinical Trial Number NCT03272399.<\/em><\/p>\n<p><em>Media contact: <\/em><a href=\"mailto:brittany.phillips@unchealth.unc.edu\"><em>Brittany Phillips<\/em><\/a><em>, Communications Specialist, UNC Health | UNC School of Medicine<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study, led by investigators in the Department of Physical Medicine &amp; Rehabilitation at the UNC School of Medicine, reveals how dietary changes significantly reduce persistent post-traumatic headaches, a common and debilitating consequence of traumatic brain injury. <\/p>\n","protected":false},"author":101835,"featured_media":10917,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,1],"tags":[41,40],"class_list":["post-10918","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-uncategorized","tag-faurot","tag-zamora","odd"],"pp_force_visibility":null,"pp_subpost_visibility":null,"pp_inherited_force_visibility":null,"pp_inherited_subpost_visibility":null,"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New Research Finds Changing Your Diet Could Ease Persistent Headaches After Brain Injury | Department of Physical Medicine &amp; 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