{"id":5274,"date":"2022-09-30T12:08:38","date_gmt":"2022-09-30T16:08:38","guid":{"rendered":"https:\/\/www.med.unc.edu\/ppmh\/?p=5274"},"modified":"2023-02-14T17:08:40","modified_gmt":"2023-02-14T22:08:40","slug":"biomedical-imaging-for-precision-diagnosis-prognosis-and-therapy-2022-11-07","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/ppmh\/2022\/09\/biomedical-imaging-for-precision-diagnosis-prognosis-and-therapy-2022-11-07\/","title":{"rendered":"Biomedical Imaging for Precision Diagnosis, Prognosis, and Therapy | November 7, 2022"},"content":{"rendered":"

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Join the UNC Program for Precision Medicine in Healthcare (PPMH) for Biomedical Imaging for Precision Diagnosis, Prognosis, and Therapy<\/strong>, a free virtual mini-symposium on Monday November 7, 2022 from 11:00am to 12:00pm ET<\/strong>. At this interactive event, you will engage in discussion with leading Precision Medicine researchers at UNC.<\/span><\/p>\n

Precision medicine harnesses cutting edge data and technology to provide prediction of disease risk and choice of optimum treatment. Biomedical imaging is an integral part of early diagnosis and individually tailored treatment. The speakers at this mini-symposium will address data-driven approaches to developing personalized treatment strategies.
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This dynamic discussion forum will explore the breadth of Precision Health initiatives at UNC and facilitate connections between colleagues with similar research interests. We hope to see you there!<\/span><\/p>\n

Presenters:<\/span><\/p>\n\n\n\n
\"\"<\/a><\/td>\n\n

Mark Shen, PhD<\/a><\/span><\/p>\n

Assistant Professor of Psychiatry & Neuroscience, Carolina Institute for Developmental Disabilities, UNC School of Medicine<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Presentation title: Longitudinal neuroimaging to study the brain development of infants with neurodevelopmental disorders<\/strong><\/p>\n

Our lab utilizes longitudinal MRIs\u00a0to chart the infant brain development of autism, fragile\u00a0X syndrome, and\u00a0Angelman syndrome.\u00a0This presentation will describe:\u00a0(1) how we conduct MRI\u00a0scans from 6-24 months of age to detect the earliest\u00a0brain features of these conditions; and (2) how\u00a0we leverage both longitudinal\u00a0neuroimaging in infants, and mechanistic studies in mouse models,\u00a0to\u00a0elucidate pathogenic mechanisms and inform potential\u00a0clinical applications.<\/p>\n

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Eran Dayan, PhD<\/a><\/span><\/p>\n

Associate Professor, Department of Radiology<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Presentation title: AI-based stratification of progression\u00a0along the Alzheimer disease continuum<\/strong><\/p>\n

Age-associated neurodegenerative diseases, such as Alzheimer\u2019s disease (AD), are becoming increasingly more prevalent. These diseases are already exerting a significant personal and financial toll on patients and their families, along with a substantial societal economic burden. The projected increase in the prevalence of AD is thus alarming, highlighting the urgent need for advances in research and care. Research I will discuss in my talk tackles the heterogeneity observed along the AD continuum. A better understanding of the heterogeneity of AD may ultimately lead to earlier and more optimal and personalized treatment strategies. Using a combination of deep learning and other model and data-driven approaches our studies aim to reveal the underlying mechanisms that lead to variation in progression rates and develop tools that may eventually be used in clinical settings.<\/p>\n

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Andrew Satterlee, PhD<\/a><\/span><\/p>\n

Brain Slice Technology Program Manager, Eshelman Institute for Innovation, Eshelman School of Pharmacy<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Presentation title: A living ex vivo<\/em> platform for functional, personalized brain cancer diagnosis<\/strong><\/p>\n

Functional\u00a0precision medicine platforms are emerging as promising strategies to improve pre-clinical drug testing and guide clinical decisions.\u00a0\u00a0We have developed an organotypic brain slice culture platform and assay which enable rapid engraftment, treatment, and analysis of patient-derived cell lines and fresh, uncultured brain tumor tissue.\u00a0\u00a0Measuring direct tumor kill of therapeutics provides additional insight to help understand which drugs will be effective against the residual tumor after resection surgery.<\/p>\n

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Agenda:<\/span><\/p>\n\n\n\n\n\n\n\n\n
10:00am-10:05<\/span><\/td>\nIntroductions<\/span><\/td>\n<\/tr>\n
10:05-10:30<\/span><\/td>\nMark Shen presentation<\/span><\/td>\n<\/tr>\n
10:30-10:55<\/span><\/td>\nEran Dayan presentation<\/span><\/td>\n<\/tr>\n
10:55-11:20<\/span><\/td>\nAndrew Satterlee presentation<\/span><\/td>\n<\/tr>\n
11:20-11:55<\/span><\/td>\nQ&A and Panel discussion<\/span><\/td>\n<\/tr>\n
11:55-12:00pm<\/span><\/td>\nClosing remarks<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Click here to register.<\/span><\/a><\/span><\/p>\n

Email precisionmedicine@med.unc.edu<\/a> for more information.<\/span><\/p>\n

Click here to download the event flyer: PPMH mini-symposium poster Nov2022<\/a>
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\"\"<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Join the UNC Program for Precision Medicine in Healthcare (PPMH) for Biomedical Imaging for Precision Diagnosis, Prognosis, and Therapy, a free virtual mini-symposium on Monday November 7, 2022 from 11:00am to 12:00pm ET. At this interactive event, you will engage in discussion with leading Precision Medicine researchers at UNC. Precision medicine harnesses cutting edge data … Read more<\/a><\/p>\n","protected":false},"author":81071,"featured_media":5809,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1,8],"tags":[],"class_list":["post-5274","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-past","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/ppmh\/wp-content\/uploads\/sites\/1356\/2023\/02\/PPMH-mini-symposium-banner-Nov2022.png","featured_image_medium":"https:\/\/www.med.unc.edu\/ppmh\/wp-content\/uploads\/sites\/1356\/2023\/02\/PPMH-mini-symposium-banner-Nov2022-300x94.png","featured_image_medium_large":"https:\/\/www.med.unc.edu\/ppmh\/wp-content\/uploads\/sites\/1356\/2023\/02\/PPMH-mini-symposium-banner-Nov2022.png","featured_image_large":"https:\/\/www.med.unc.edu\/ppmh\/wp-content\/uploads\/sites\/1356\/2023\/02\/PPMH-mini-symposium-banner-Nov2022.png","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/ppmh\/wp-content\/uploads\/sites\/1356\/2023\/02\/PPMH-mini-symposium-banner-Nov2022-150x150.png","featured_image_alt":"Banner for Biomedical Imaging for Precision Diagnosis, Prognosis, & Therapy Symposia","category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/ppmh\/category\/news\/"},{"name":"past","link":"https:\/\/www.med.unc.edu\/ppmh\/category\/past\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/posts\/5274","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/users\/81071"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/comments?post=5274"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/posts\/5274\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/media\/5809"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/media?parent=5274"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/categories?post=5274"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/ppmh\/wp-json\/wp\/v2\/tags?post=5274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}