{"id":10105,"date":"2021-02-17T11:56:33","date_gmt":"2021-02-17T16:56:33","guid":{"rendered":"https:\/\/www.med.unc.edu\/psych\/cecmh\/?p=10105"},"modified":"2021-02-17T11:56:33","modified_gmt":"2021-02-17T16:56:33","slug":"specific-genes-in-placenta-may-predict-size-of-babys-brain-and-risk-for-schizophrenia","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/psych\/cecmh\/specific-genes-in-placenta-may-predict-size-of-babys-brain-and-risk-for-schizophrenia\/","title":{"rendered":"Specific genes in placenta may predict size of baby\u2019s brain and risk for schizophrenia"},"content":{"rendered":"<p>A genetic scoring of schizophrenia-related genes in the placenta can predict the size of a baby\u2019s brain at birth and its rate of cognitive development, which, dependent on other factors, may lead to schizophrenia later in life, according to a study published today in the <em><a href=\"https:\/\/www.pnas.org\/content\/118\/7\/e2019789118\" target=\"_blank\" rel=\"noopener noreferrer\">Proceedings of the the National Academy of the Sciences (PNAS)<\/a><\/em>. Researchers at the Lieber Institute for Brain Development (LIBD) and the University of North Carolina (UNC) School of Medicine used MRI scans at UNC from newborns and cognitive development measures for the first two years of life to uncover the finding. They noted that this was most significant in males.<\/p>\n<p>\u201cBy identifying the specific genes activated in the placenta that appear to be unique for schizophrenia risk, we have zeroed in on a set of biological processes that could be targeted to improve placental health and reduce schizophrenia risk,\u201d says Daniel R. Weinberger, M.D., CEO &amp; Director of the Lieber Institute. \u201cTo date, prevention from early in life has seemed unapproachable if not unimaginable, but these new insights offer possibilities to change the paradigm.\u201d<\/p>\n<p>Weinberger notes that that most of the children with higher schizophrenia gene scoring in the placenta will not develop schizophrenia because other genetic and environmental factors will compensate for these placental effects later in development. But, he says, in principle, individuals who have other schizophrenia genetic risk factors and early life complications during pregnancy may not be able to compensate and will develop the illness, particularly if they are males&#8230;.(<a href=\"https:\/\/news.unchealthcare.org\/2021\/02\/specific-genes-in-placenta-may-predict-size-of-babys-brain-and-risk-for-schizophrenia\/\" target=\"_blank\" rel=\"noopener noreferrer\">read the full article here<\/a>)<\/p>\n<p>&nbsp;<\/p>\n<p><em>Original story and image by UNC Health Newsroom | February 8, 2021<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A genetic scoring of schizophrenia-related genes in the placenta can predict the size of a baby\u2019s brain at birth and its rate of cognitive development, which, dependent on other factors, may lead to schizophrenia later in life, according to a study published today in the Proceedings of the the National Academy of the Sciences (PNAS). &hellip; <a href=\"https:\/\/www.med.unc.edu\/psych\/cecmh\/specific-genes-in-placenta-may-predict-size-of-babys-brain-and-risk-for-schizophrenia\/\" aria-label=\"Read more about Specific genes in placenta may predict size of baby\u2019s brain and risk for schizophrenia\">Read more<\/a><\/p>\n","protected":false},"author":97082,"featured_media":10107,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[52,2,1],"tags":[],"class_list":["post-10105","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-home-page-news","category-news","category-uncategorized","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Specific genes in placenta may predict size of baby\u2019s brain and risk for schizophrenia - UNC Center for Excellence in Community Mental Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/psych\/cecmh\/specific-genes-in-placenta-may-predict-size-of-babys-brain-and-risk-for-schizophrenia\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Specific genes in placenta may predict size of baby\u2019s brain and risk for schizophrenia - UNC Center for Excellence in Community Mental Health\" \/>\n<meta property=\"og:description\" content=\"A genetic scoring of schizophrenia-related genes in the placenta can predict the size of a baby\u2019s brain at birth and its rate of cognitive development, which, dependent on other factors, may lead to schizophrenia later in life, according to a study published today in the Proceedings of the the National Academy of the Sciences (PNAS). &hellip; 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