Associate Chair of Research Training and Education
UNC Hospitals – Chapel Hill
UNC Mental Health Specialists – Chapel Hill
Education and Training:
B.A., Brown University, Psychology
Post-Baccalaureate Special Student, Brown University
M.D., University of Virginia School of Medicine
Community Medicine Internship, University of Colorado Health Sciences Center
Residency, Psychiatry, University of Colorado Health Sciences Center
Fellowship, Preventive Medicine, The University of North Carolina at Chapel Hill
M.P.H., School of Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill
Robert Wood Johnson Clinical Scholar, The University of North Carolina at Chapel Hill
Bradley Gaynes MD, MPH, is a Professor and the Associate Chair of Research Training and Education in the Department of Psychiatry at the University of North Carolina at Chapel Hill. His post-graduate training has included a Robert Wood Johnson Clinical Scholar Fellowship at the University of North Carolina, where he also received his Master of Public Health degree in Epidemiology and completed a fellowship in Preventive Medicine. Dr. Gaynes works at the crossroads between clinical trials research and mental health services research (including comparative effectiveness reviews), and he focuses his clinical and research efforts on treatment resistant depression and on improving the delivery of depression care in non-psychiatric settings, including primary care, obstetrical, and HIV practices.
As a clinical trials researcher, Dr. Gaynes has participated in seminal work on primary care depression management. He served as the Director of the UNC Regional Center for STAR*D. Currently, Dr. Gaynes is PI on an NIMH-funded R-34 adapting measure-based care to manage depressed HIV patients in Cameroon, and he is co-PI on an NIMH-funded R-01 assessing whether HIV outcomes in depressed HIV patients are better following randomization to measurement-based care compared to usual care.
As a mental health services researcher, Dr. Gaynes has previously served as PI for the U.S. Preventive Services Task Force’s evidence report on screening for suicide risk in primary care; as co-investigator on a Task Force report on screening for depression in primary care; and as PI on a recently completed AHRQ-funded comparative effectiveness review of the effectiveness of nonpharmacologic interventions in the management of treatment refractory depression. He is currently an investigator on the UNC/RTI collaborative project, “Comprehensive EPC Comparative Effectiveness Reviews for Effective Health Care”, and he has just completed a comparative effectiveness review of the available pharmacologic and nonpharmacologic treatments as first- or second-step interventions for major depressive disorder.