Twin Study - Recruiting Ended 2/2014

We are conducting a study of prenatal and neonatal brain development in twins. If you are having same gender twins, you may be eligible to participate.

Details of this Study


Twins offer a very unique and important way of studying brain development and exploring the potential relationship of individual variations in brain structure and later development. By comparing similarities in paternal (identical) and fraternal (nonidentical) twins, we can determine the role that genetic and environmental factors play in brain development. This knowledge will improve our understanding of normal brain development and may ultimately provide insights into brain structure differences in neurodevelopmental disorders.

The study involves two visits for prenatal ultrasounds: once during the second trimester and once during the third trimester. You will also be asked medical history questions by a program coordinator or study nurse.

If your twins are the same gender, one to two weeks after your twins are born, they will have an unsedated MRI of their brains. We will also provide free zygosity testing to determine if your twins are paternal or fraternal.

A Developmental Assessment and an unsedated MRI will be done for each twin when they are 1, 2, 4, and 6 years of age. You will receive $50 for each prenatal study visit and $50 per child for each postnatal visit, for a potential total of $600. You will be reimbursed for travel and parking expenses as well.

By participating in this study you will be helping improve our understanding about normal brain and cognitive development in twins. This is a voluntary study, you will be compensated, and all information gathered is confidential.

If you are interested in participating in this study, please contact Dianne Evans, M.A., Twin Study Coordinator (919-843-2389) or email: ddevans@med.unc.edu. She will explain the study in more detail and answer any questions that you may have.

 

Frequently Asked Questions

Who is eligible for the Early Brain Development Study Twins?

Any mother with a twin pregnancy at any gestational age.

Will it cost me anything to be in this study?

There are no costs to subjects for participating in this research study.

Will my participation in this Study be kept confidential?

Yes, all information gathered is kept strictly confidential.

I would like to participate in this study but I don’t drive/have a car?

Transportation can be provided if needed.

Who can’t participate in the Early Brain Development Study Twins?

Mothers with HIV, any known chromosomal abnormality, or any major congenital abnormality.

Will I be paid for participating?

You will receive $50 for each prenatal study visit and $50 per child for each postnatal visit, for a potential of $600. You will be reimbursed for travel expenses and parking.

Why participate in this study?

By participating in this study you will be helping improve our understanding about normal brain and cognitive development in twins.

Are there any risks?

The MRI scanner is approved by the Food and Drug Administration for use in children and there is no evidence that the scans have any harmful effects. The ultrasound machine and the MRI machine do not use x-ray or radiation.

Remember,

  • This is a voluntary study
  • You will be compensated
  • No medicines or sedation are used
  • No x-ray or radiation is used
  • All information regarding your and your children’s involvement in this study is kept strictly confidential.

How do I learn more about joining this study?

If you are interested in participating in this study, please contact Dianne Evans, M.A. at the number below. She can explain the study in more detail and answer any questions that you may have.

Dianne Evans, M.A.
Twin Study Coordinator
Voice mail: (919) 843-2389
(866) 849-0541 (toll free)

Related Links

Twin Brochure

Twin Brochure in Spanish