{"id":2451,"date":"2018-08-15T13:33:57","date_gmt":"2018-08-15T17:33:57","guid":{"rendered":"https:\/\/www.med.unc.edu\/psych\/research\/prime\/"},"modified":"2026-06-01T09:17:59","modified_gmt":"2026-06-01T13:17:59","slug":"prime","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/","title":{"rendered":"PRIME: Early Psychosis Research Program"},"content":{"rendered":"<p><em>The PRIME: Early Psychosis Research Program was established to better understand the causes, course and treatment of &#8220;Clinical High Risk Symptoms.&#8221; These symptoms include changes in thinking, mood and perception.<\/em><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-19898 aligncenter\" src=\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-300x128.jpg\" alt=\"\" width=\"300\" height=\"128\" srcset=\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-300x128.jpg 300w, https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-1024x438.jpg 1024w, https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-768x328.jpg 768w, https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-600x256.jpg 600w, https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg 1130w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<div>\n<p style=\"text-align: center\"><strong>To find out if you might be eligible to participate in one <\/strong><strong>of our studies, please complete this questionnaire:<\/strong><\/p>\n<a class=\"btn btn-primary btn-lg  oscitas-bootstrap-container\" target=\"_self\" href=\"#https:\/\/unc.az1.qualtrics.com\/jfe\/form\/SV_6mwv1WEGS2HI9Lv?Q_JFE=qdg\">Take a Simple Survey<\/a>\n<hr \/>\n<p><em>People experiencing the following symptoms may be at increased risk for developing an illness like psychosis:<\/em><br \/>\n<div role=\"tablist\" class=\"panel-group yourcustomclass oscitas-bootstrap-container\" id=\"unc-accordion-0\">\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-0\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h4 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-0\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-0\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-0\">\n                Unusual Thinking            <\/button>\n\n        <\/h4>\n\n    <\/div>\n\n    <div id=\"details-0-0\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Confusion about what is real or imaginary.<\/li>\n<li>Frequent d\u00e9j\u00e0 vu.<\/li>\n<li>Wondering if people can read minds, hear thoughts.<\/li>\n<li>Mystical\/philosophical\/religious ideas.<\/li>\n<li>The familiar feels strange, confusing, threatening, or has special meaning.<\/li>\n<\/ul>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-1\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h4 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-1\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-1\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-1\">\n                Perceptual Abnormalities            <\/button>\n\n        <\/h4>\n\n    <\/div>\n\n    <div id=\"details-0-1\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>It seems that the mind\/eyes\/ears are playing tricks or are misperceiving reality (for example mistaking a dog barking for someone calling out a name).<\/li>\n<li>Changes in perceptual sensitivity&#8211;heightened or dulled.<\/li>\n<li>Unexpected perceptual changes, noises, lights, shadows, geometrical designs, and whispers or hearing one&#8217;s name called.<\/li>\n<li>Increased sensitivity to smells and tastes.<\/li>\n<\/ul>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-2\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h4 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-2\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-2\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-2\">\n                Suspiciousness            <\/button>\n\n        <\/h4>\n\n    <\/div>\n\n    <div id=\"details-0-2\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Notions of being watched, singled out, talked about, or plotted against, even if unsure whether it is true.<\/li>\n<\/ul>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-3\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h4 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-3\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-3\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-3\">\n                Disorganized Thinking            <\/button>\n\n        <\/h4>\n\n    <\/div>\n\n    <div id=\"details-0-3\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Confused or muddled thinking.<\/li>\n<li>Using the wrong words, talking about things irrelevant to context of conversations, or going off track.<\/li>\n<li>Difficulty paying attention or remembering simple things.<\/li>\n<\/ul>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-4\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h4 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-4\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-4\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-4\">\n                Grandiose Ideas            <\/button>\n\n        <\/h4>\n\n    <\/div>\n\n    <div id=\"details-0-4\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Notions of being especially important, talented, gifted, powerful, or superior to others.<\/li>\n<\/ul>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-5\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h4 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-5\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-5\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-5\">\n                Social Anhedonia or Withdrawal            <\/button>\n\n        <\/h4>\n\n    <\/div>\n\n    <div id=\"details-0-5\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Decreased interest in spending time or talking with friends or family.<\/li>\n<li>Less interested in everyday activities or hobbies.<\/li>\n<li>Prefer to be alone.<\/li>\n<\/ul>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<h2><strong>ProCAN: Psychosis Risk Outcome Network<\/strong><\/h2>\n<p><em>A research study for young people with mental health concerns<\/em><\/p>\n<p>The ProCAN study is recruiting young people who are at Clinical High Risk (CHR) \u2013 meaning they&#8217;re experiencing some early signs or changes that suggest they might be at a higher risk of developing conditions like psychosis in the future.<\/p>\n<p><strong>Eligibility <\/strong><\/p>\n<h4>Some individuals may be at higher risk of developing psychosis than others. This study is recruiting people who have experiences or circumstances that may put them at higher risk.<\/h4>\n<p><strong>You may be eligible for this study if you meet the following criteria: <\/strong><\/p>\n<ul>\n<li>Ages 17-30<\/li>\n<li>Noticing a recent change in thinking, behavior, or experiences, such as:<\/li>\n<li>Confusion about what is real or imaginary<\/li>\n<li>Feeling not in control of your own thoughts of ideas<\/li>\n<li>Feeling suspicious or paranoid<\/li>\n<li>Having experiences that may not be real, such as hearing sounds or seeing things that may not be there<\/li>\n<li>Having trouble communicating clearly<\/li>\n<\/ul>\n<p>To determine if you are eligible, you would complete an interview and other tests such as a physical exam, blood tests and a review of your medical history. If eligible, you will then be enrolled into the study and randomly assigned to 1 of three treatments:<\/p>\n<ul>\n<li>Low dose MT1988<\/li>\n<li>High dose MT1988<\/li>\n<li>Placebo<\/li>\n<\/ul>\n<p>The study is blinded, so you will not know what treatment you are receiving.<\/p>\n<p><strong>What is the purpose of this study? <\/strong><\/p>\n<p>The primary purpose of this study is to:\u00a0<\/p>\n<ul>\n<li>Understand how the investigational medicine (MT1988) affects certain &#8216;clues&#8217; in your body and brain. These &#8216;clues&#8217; are like internal signals. We are looking for specific signals that might show us how MT1988 is affecting your body and brain. We call these &#8216;biomarkers&#8217;.<\/li>\n<li>The study is also looking at &#8216;clues&#8217; related to your <strong>thinking skills<\/strong> and <strong>clinical observations<\/strong> (how you&#8217;re feeling and functioning).<\/li>\n<li>The goal is to see if the medicine, at two different dose levels, changes these clues.<\/li>\n<\/ul>\n<p><strong>What Would I Do in this Study if I am enrolled?<\/strong><\/p>\n<p>You will come back to the clinic for 8 visits over the next three months. The visits would entail:<\/p>\n<ul>\n<li>Clinical Interviews\n<ul>\n<li>These focus on questions about your daily life and about different experiences and symptoms.<\/li>\n<\/ul>\n<\/li>\n<li>Biological Assessments\n<ul>\n<li>These include saliva tests, blood tests, and Electroencephalography (EEG) brain scans.<\/li>\n<\/ul>\n<\/li>\n<li>Cognitive Tests\n<ul>\n<li>These focus on memory, attention, concentration and learning.<\/li>\n<\/ul>\n<\/li>\n<li>Investigational drug\/placebo\n<ul>\n<li>Continue taking the assigned treatment throughout the study.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>Why Participate in Research?<\/strong><\/p>\n<p>You will have the opportunity to participate in a research study where you will receive study-related assessment, monitoring, education, and receive investigational drug.<\/p>\n<p>Your participation in research may help contribute in ways that will help young people with mental health concerns in the future.<\/p>\n<ul>\n<li>Better understand how the medicine works.<\/li>\n<li>Help doctors decide on the best timing and approach for early support.<\/li>\n<li>Speed up the development of even better treatments in the future for people like you.<\/li>\n<\/ul>\n<p>Reimbursement for your time and travel is provided.<\/p>\n<p><em>If you are interested in learning more about the ProCAN study, please contact the PRIME staff. They will be happy to answer your questions and provide you with more information.<\/em><\/p>\n<p>&nbsp;<\/p>\n<div class = \"alert alert-info  oscitas-bootstrap-container\">\n<h2><strong>Contact PRIME<\/strong><\/h2>\n<h4>Call 877-PRIME-19<\/h4>\n<p>Jennifer Nieri, LCSW<br \/>\n<span class=\"baec5a81-e4d6-4674-97f3-e9220f0136c1\">Phone:\u00a0 (919) 966-8341<\/span><br \/>\n<a href=\"mailto:jennifer_nieri@med.unc.edu\">jennifer_nieri@med.unc.edu<\/a><\/p>\n<p>Rachel Bleggi, BS<br \/>\nPhone: (919) 962-7940<br \/>\n<a href=\"mailto:rachel_bleggi@med.unc.edu\">rachel_bleggi@med.unc.edu<\/a><\/p>\n<p><a href=\"mailto:PRIME@med.unc.edu\">PRIME@med.unc.edu<\/a><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<div>\n<p><em>If you are not currently experiencing any of the above symptoms, but are still interested in volunteering for a research study, view our <a href=\"https:\/\/www.med.unc.edu\/psych\/oasis\/research\/volunteer-for-a-research-study\/\">Volunteer for a Research Study page<\/a> to learn more.<\/em><\/p>\n<p>&nbsp;<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The PRIME: Early Psychosis Research Program was established to better understand the causes, course and treatment of &#8220;Clinical High Risk Symptoms.&#8221; These symptoms include changes in thinking, mood and perception. To find out if you might be eligible to participate in one of our studies, please complete this questionnaire: People experiencing the following symptoms may &hellip; <a href=\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/\" aria-label=\"Read more about PRIME: Early Psychosis Research Program\">Read more<\/a><\/p>\n","protected":false},"author":1369,"featured_media":0,"parent":6868,"menu_order":36,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2451","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PRIME: Early Psychosis Research Program | Department of Psychiatry<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PRIME: Early Psychosis Research Program | Department of Psychiatry\" \/>\n<meta property=\"og:description\" content=\"The PRIME: Early Psychosis Research Program was established to better understand the causes, course and treatment of &#8220;Clinical High Risk Symptoms.&#8221; These symptoms include changes in thinking, mood and perception. To find out if you might be eligible to participate in one of our studies, please complete this questionnaire: People experiencing the following symptoms may &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Psychiatry\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-01T13:17:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1130\" \/>\n\t<meta property=\"og:image:height\" content=\"483\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/\",\"url\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/\",\"name\":\"PRIME: Early Psychosis Research Program | Department of Psychiatry\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/psych\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-300x128.jpg\",\"datePublished\":\"2018-08-15T17:33:57+00:00\",\"dateModified\":\"2026-06-01T13:17:59+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg\",\"width\":1130,\"height\":483},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/psych\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\",\"item\":\"https:\/\/www.med.unc.edu\/psych\/research\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Psychiatry Research Programs and Labs\",\"item\":\"https:\/\/www.med.unc.edu\/psych\/research\/programs\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"PRIME: Early Psychosis Research Program\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/psych\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/psych\/\",\"name\":\"Department of Psychiatry\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.med.unc.edu\/psych\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/psych\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.med.unc.edu\/psych\/#organization\",\"name\":\"UNC Chapel Hill Department of Psychiatry\",\"url\":\"https:\/\/www.med.unc.edu\/psych\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/psych\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2017\/06\/Psychiatry_logo_rgb_h.png\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2017\/06\/Psychiatry_logo_rgb_h.png\",\"width\":982,\"height\":151,\"caption\":\"UNC Chapel Hill Department of Psychiatry\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/psych\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"PRIME: Early Psychosis Research Program | Department of Psychiatry","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/","og_locale":"en_US","og_type":"article","og_title":"PRIME: Early Psychosis Research Program | Department of Psychiatry","og_description":"The PRIME: Early Psychosis Research Program was established to better understand the causes, course and treatment of &#8220;Clinical High Risk Symptoms.&#8221; These symptoms include changes in thinking, mood and perception. To find out if you might be eligible to participate in one of our studies, please complete this questionnaire: People experiencing the following symptoms may &hellip; Read more","og_url":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/","og_site_name":"Department of Psychiatry","article_modified_time":"2026-06-01T13:17:59+00:00","og_image":[{"width":1130,"height":483,"url":"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/","url":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/","name":"PRIME: Early Psychosis Research Program | Department of Psychiatry","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/psych\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo-300x128.jpg","datePublished":"2018-08-15T17:33:57+00:00","dateModified":"2026-06-01T13:17:59+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#primaryimage","url":"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg","contentUrl":"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2026\/06\/PRIME-Logo.jpg","width":1130,"height":483},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/prime\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/psych\/"},{"@type":"ListItem","position":2,"name":"Research","item":"https:\/\/www.med.unc.edu\/psych\/research\/"},{"@type":"ListItem","position":3,"name":"Psychiatry Research Programs and Labs","item":"https:\/\/www.med.unc.edu\/psych\/research\/programs\/"},{"@type":"ListItem","position":4,"name":"PRIME: Early Psychosis Research Program"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/psych\/#website","url":"https:\/\/www.med.unc.edu\/psych\/","name":"Department of Psychiatry","description":"","publisher":{"@id":"https:\/\/www.med.unc.edu\/psych\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/psych\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.med.unc.edu\/psych\/#organization","name":"UNC Chapel Hill Department of Psychiatry","url":"https:\/\/www.med.unc.edu\/psych\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/psych\/#\/schema\/logo\/image\/","url":"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2017\/06\/Psychiatry_logo_rgb_h.png","contentUrl":"https:\/\/www.med.unc.edu\/psych\/wp-content\/uploads\/sites\/839\/2017\/06\/Psychiatry_logo_rgb_h.png","width":982,"height":151,"caption":"UNC Chapel Hill Department of Psychiatry"},"image":{"@id":"https:\/\/www.med.unc.edu\/psych\/#\/schema\/logo\/image\/"}}]}},"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/pages\/2451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/users\/1369"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/comments?post=2451"}],"version-history":[{"count":10,"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/pages\/2451\/revisions"}],"predecessor-version":[{"id":19899,"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/pages\/2451\/revisions\/19899"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/pages\/6868"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/psych\/wp-json\/wp\/v2\/media?parent=2451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}