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Assistant Professor of Radiology, Vascular-Interventional Radiology Co-Program Director for Interventional Radiology Residencies


Nicole Keefe, MD, has always been interested in innovating while helping patients. As the first person involved in medicine in her family, she found it to be an extremely rewarding career, seeing how quickly patients can improve with different minimally invasive therapies.
Dr. Keefe completed her General Surgery internship, Diagnostic and Interventional Radiology residency, and Interventional Radiology fellowship at the University of Virginia in Charlottesville, VA. Following this, she spent over a year in private practice in Raleigh. She joined UNC’s Department of Radiology in January 2022 as Assistant Professor. She currently serves as Associate Program Director for Interventional Radiology.


Dr. Keefe’s clinical interests include complex IVC filter removals and venous reconstructions, vertebral augmentation, women’s health, and endoleak treatment.


Her research interests include education, pregnancy and vascular disease. She serves on the American College of Radiology expert panel on vascular imaging.

Philosophy of Care

I believe in always providing patients with the best care for their problems, whether that be with another provider or with me. Our job as physicians is “First, do no harm.” I try to ensure that the procedures I do offer the highest benefit with the lowest risk possible. I think it’s important for patients to understand all of the treatment options available to them for each disease pathology in order to make a well-informed decision on their care.


  • Medical School: SUNY Upstate Medical University
  • Internship: General Surgery at the University of Virginia
  • Residency: Diagnostic & Interventional Radiology at the University of Virginia
  • Fellowship: Interventional Radiology at the University of Virginia


For a list of Dr. Keefe’s publications, see her ORCID profile.


Nicole Keefe, MD
  • Radiology