{"id":2354,"date":"2025-11-17T10:42:09","date_gmt":"2025-11-17T15:42:09","guid":{"rendered":"https:\/\/www.med.unc.edu\/radiology\/kohilab\/?post_type=ud_entry&#038;p=2354"},"modified":"2025-11-25T12:14:18","modified_gmt":"2025-11-25T17:14:18","slug":"maureen-kohi-md","status":"publish","type":"ud_entry","link":"https:\/\/www.med.unc.edu\/radiology\/kohilab\/people\/maureen-kohi-md\/","title":{"rendered":"Maureen Kohi, MD, FSIR, FCIRSE, FAHA"},"content":{"rendered":"<p>I am the Ernest H. Wood Distinguished Professor and Chair of the Department of Radiology at the University of North Carolina at Chapel Hill (UNC-CH). My academic career has focused on advancing minimally invasive image-guided therapies for women\u2019s health and on elucidating sex-based differences in vascular disease. Specifically, my research investigates minimally invasive treatments for symptomatic uterine fibroids and adenomyosis, strategies to optimize the management of patients with morbidly adherent placenta, and the differential presentation and outcomes of peripheral arterial disease in women. I am recognized internationally as an expert in image-guided interventions for women with fibroids and adenomyosis, including uterine artery embolization (UAE) and MR-guided focused ultrasound (MRgFUS).<\/p>\n<p>I have served as principal investigator (PI) or co-investigator (Co-I) on numerous federally and industry-funded clinical trials, several of which have been practice-changing. For example, I was Co-I on the pivotal trial establishing the safety and efficacy of MRgFUS compared to placebo, and subsequently on the trial comparing UAE with MRgFUS, which demonstrated the superiority of UAE for symptom relief. These investigations have directly informed patient care, yielded numerous peer-reviewed publications, and led to multiple invited podium presentations at national and international meetings. Currently, I serve as the global PI of a first-in-kind, large-scale, multicenter observational study evaluating outcomes of drug-eluting devices in patients with peripheral arterial disease. Importantly, this trial is designed to enroll more than 40% women\u2014addressing a critical gap in sex-specific outcomes research and enabling novel insights into treatment disparities that have historically been underexplored in vascular studies. In addition to my scientific contributions, I have extensive experience with the operational and administrative aspects of clinical research, including study design, procedural performance, outcome evaluation, staffing, budgeting, and cross-disciplinary collaboration with clinical and industry partners.<\/p>\n<h2>Ongoing and recently completed projects<\/h2>\n<div role=\"tablist\" class=\"panel-group  oscitas-bootstrap-container\" id=\"unc-accordion-0\">\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-0\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-0\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-0\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-0\">\n                Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-0\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nBoston Scientific Corporation Kohi (PI) 3\/29\/2021 \u2013 01\/01\/2028<\/p>\n<p><strong>Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature<\/strong><br \/>\nThis trial evaluates real-world patients treated with commercially available drug-eluting devices for peripheral vascular lesions. As a post-market study, it aims to enroll more than 40% women, addressing their historical underrepresentation in peripheral vascular disease trials.<\/p>\n<p>Role: <strong>Global Principal Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-1\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-1\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-1\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-1\">\n                N-Butyl-2-Cyanoacrylate Embolization of Fallopian Tubes            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-1\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nSociety of Interventional Radiology Foundation\u00a0Stewart (Co-PI) 7\/1\/2020 \u201306\/30\/2021<\/p>\n<p><strong>N-Butyl-2-Cyanoacrylate Embolization of Fallopian Tubes<\/strong><br \/>\nThis translational study aims to investigate the outcomes of fallopian tube embolization using n-butyl-2-cyanoacrylate inrabbits<\/p>\n<p>Role: <strong>Co-Principal Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-2\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-2\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-2\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-2\">\n                Comparing Options for Management: Patient-Centered Results for Uterine Fibroids            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-2\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nPCORI\/AHRQ Stewart (Co-I) 9\/30\/2015 \u2013 10\/1\/2020<\/p>\n<p><strong>Comparing Options for Management: Patient-Centered Results for Uterine Fibroids<\/strong><br \/>\nThis trial aimed to design and establish a uterine fibroid registry to provide comparative effectiveness data regarding the various uterine fibroid treatments.<\/p>\n<p>Role: <strong>Co-Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-3\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-3\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-3\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-3\">\n                Pilot Trial of Arterial Embolization Following Cesarean Hysterectomy            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-3\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nUCSF Resource Allocation Program\u00a0Kohi (PI) 7\/1\/2015 \u2013 6\/30\/2016<\/p>\n<p><strong>Pilot Trial of Arterial Embolization Following Cesarean Hysterectomy<\/strong><br \/>\nThis trial aimed to evaluate the safety and efficacy of artery embolization for the treatment of women with placenta accrete spectrum following hysterectomy.<\/p>\n<p>Role: <strong>Principal Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-4\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-4\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-4\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-4\">\n                Accelerated Ultrasound Ablation of Uterine Fibroids with MR guided Vascular Targeting            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-4\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nFocused Ultrasound Foundation Kohi (PI) 8\/1\/2014 \u2013 8\/1\/2016<\/p>\n<p><strong>Accelerated Ultrasound Ablation of Uterine Fibroids with MR guided Vascular Targeting<\/strong><br \/>\nThis pilot study aimed to evaluate the safety and efficacy of performing MR-guided focused ultrasound, targeting the vascular pedicle of symptomatic uterine fibroids.<\/p>\n<p>Role: <strong>Principal Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-5\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-5\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-5\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-5\">\n                THE FIRSTT TRIAL: Assessing Outcomes of Minimally Invasive Leiomyoma Therapies            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-5\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nNIH R01HD060503 Stewart (Co-I) 8\/1\/2013 \u2013 7\/1\/2016<\/p>\n<p><strong>THE FIRSTT TRIAL: Assessing Outcomes of Minimally Invasive Leiomyoma Therapies<\/strong><br \/>\nThis prospective randomized controlled trial aimed to compare short and long-term outcomes, adverse events, predictors of outcome, and costs of MR-guided focused ultrasound vs. uterine artery embolization (UAE) for the treatment of symptomatic uterine fibroids.<\/p>\n<p>Role:<strong> Co-Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-6\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-6\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-6\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-6\">\n                The PROMISe Trial: Pilot Randomized Trial of MRI-Guided Focused Ultrasound in Symptomatic Uterine Fibroids            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-6\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\nNIH 5K12HD001262-12 Jacoby (Co-I) 6\/1\/2011 \u2013 12\/31\/2012<\/p>\n<p><strong>The PROMISe Trial: <\/strong><strong>Pilot Randomized Trial of MRI-Guided Focused Ultrasound in Symptomatic Uterine Fibroids<\/strong><br \/>\nThis pilot, randomized, placebo-controlled trial aimed to evaluate the feasibility of a gull-scale placebo-controlled trial of MR-guided focused ultrasound for fibroids and obtain estimates of safety and efficacy.<\/p>\n<p>Role:<strong> Co-Investigator<\/strong><br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div>\n<\/div>\n","protected":false},"featured_media":2295,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"ud_division":[5],"class_list":["post-2354","ud_entry","type-ud_entry","status-publish","format-standard","has-post-thumbnail","hentry","ud_division-researchers","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Maureen Kohi, MD, FSIR, FCIRSE, FAHA - Kohi Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/radiology\/kohilab\/people\/maureen-kohi-md\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Maureen Kohi, MD, 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