{"id":237,"date":"2023-09-01T17:47:56","date_gmt":"2023-09-01T17:47:56","guid":{"rendered":"https:\/\/www.med.unc.edu\/radiology\/research\/clinical-research\/clinical-trials\/"},"modified":"2026-03-16T14:43:05","modified_gmt":"2026-03-16T18:43:05","slug":"clinical-trials","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/radiology\/research\/clinical-research\/clinical-trials\/","title":{"rendered":"Clinical Trials"},"content":{"rendered":"<p>UNC Radiology clinical and radiological science faculty are engaged in multiple clinical trials. Our studies investigate new approaches to diagnostic radiology and treating diseases and conditions.\u00a0The clinical trials include close collaboration between scientists and physicians from many areas of expertise. All trials are overseen by the Institutional Review Board (IRB) to ensure the highest ethical standards.<\/p>\n<p>Radiology Specialty:<\/p>\n<ul>\n<li><a href=\"#abs\">Abdominal Imaging<\/a><\/li>\n<li><a href=\"#breast\">Breast Imaging<\/a><\/li>\n<li><a href=\"#ir\">Intervention Radiology<\/a><\/li>\n<li><a href=\"#MIT\">Molecular Imaging &amp; Therapeutics<\/a><\/li>\n<li><a href=\"#neuro\">Neuroradiology<\/a><\/li>\n<li><a href=\"#peds\">Pediatrics<\/a><\/li>\n<\/ul>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\">\n<div class=\"panel-heading oscitas-bootstrap-container\">\n<h2><a id=\"abs\"><\/a>Abdominal Imaging<\/h2>\n<\/div>\n<\/div>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-4995 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-150x150.jpg\" alt=\"Ersan Alton headshot. Male with short dark hair and eyes wearing glasses looking at the camera. He is wearing a blue shirt, red tie, and black suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/AI_AltunErsan_Web_220923-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Multiparametric MRI (mpMRI) for Preoperative Staging and Treatment Planning for Newly-Diagnosed Prostate Cancer<\/h3>\n<p>Purpose: The purpose of this research study is to test if a new MRI imaging exam called mpMRI combined with PIRADSv2 is useful for evaluating prostate cancer in finding aggressive diseases.<br \/>\nPI: Ersan Altun, MD<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03697148?term=NCT03697148&amp;draw=2&amp;rank=1\">ClinicalTrials.gov<\/a><\/div>\n<\/div>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\">\n<div class=\"panel-heading oscitas-bootstrap-container\">\n<h2><a id=\"breast\"><\/a>Breast Imaging<\/h2>\n<\/div>\n<\/div>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5096 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-150x150.jpg\" alt=\"Cherie Kuzmiak headshot. A female with a pixie cut and brown eyes smiling at the camera. She is wearing a light pink shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Reproductive Axis Maturation in the Early Post- Menarchal Years: a Pilot Study<\/h3>\n<p>The purpose of this study is to determine the physiologic and pathophysiologic<br \/>\nunderpinnings of irregular menstrual cycles among adolescents in the early postmenarchal<br \/>\nperiod.<br \/>\nPI: Cherie Kuzmiak, DO<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03233191?term=NCT03233191&amp;draw=2&amp;rank=1\">Clinicaltrials.gov<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5096 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-150x150.jpg\" alt=\"Cherie Kuzmiak headshot. A female with a pixie cut and brown eyes smiling at the camera. She is wearing a light pink shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/BI_KuzmiakCherie_web-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>TMIST<\/h3>\n<p>Purpose: To compare the proportions of participants in the Tomosynthesis (TM) and Digital Mammography (DM) study arms experiencing the occurrence of &#8220;advanced&#8221; breast cancer at any time during a period of 4.5 years from randomization, including the period of active screening and a period of clinical follow-up after the last screen (T4).<br \/>\nParticipants: Women being screened for breast cancer.<br \/>\nPI: Cherie Kuzmiak, DO<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information check out <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03233191?term=NCT03233191&amp;draw=2&amp;rank=1\">clinicaltrials.gov<\/a><\/div>\n<\/div>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\">\n<div class=\"panel-heading oscitas-bootstrap-container\">\n<h2><a id=\"ir\"><\/a>Interventional Radiology<\/h2>\n<\/div>\n<\/div>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-8082 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-150x150.jpg\" alt=\"Nikki Keefe's headshot. Female with long, honey blonde hair and green eyes smiling at the camera. She is wearing a white doctor's coat, and black blouse underneath. She is standing in front of a glass building with greenery in front it it.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702-600x600.jpg 600w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KeefeNikki_web_250702.jpg 2000w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Local Radiofrequency Ablation plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors<\/h3>\n<p>Purpose: To determine if the combination of kyphoplasty with Osteocool ablation plus radiation therapy results in improved patient pain management for the treatment of thoracic and lumbar spine tumors.<br \/>\nPI: Nicole Keefe, MD<br \/>\nActive Enrolling<\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5318 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-150x150.jpg\" alt=\"Nima Kokabi's headshot. A male with dark brown hair and eyes smiling at the camera. He is wearing a white shirt, bright yellow tie, and dark blue suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Observational basket trial to collect tissue to develop and train a live tumor diagnostic platform (ELEPHAS-02)<\/h3>\n<p>The primary objective of this study is to train and validate the ELEPHAS live tumor diagnostic platform and determine the ex-vivo accuracy of the Cybrid Score using in-vivo RECIST 1.1 as the reference method.<br \/>\nParticipants: We will enroll up to 416 subjects across all study sites. Subjects suspected of or diagnosed with Stage IV\/metastatic and undergoing biopsy for the following:(1) Lung: Non-small cell lung cancer (NSCLC), (2) Head and Neck: Squamous Cell Carcinoma, (HNSCC), excluding nasopharyngeal and salivary gland cancers, (3) Kidney: Clear Cell Renal Cell Carcinoma (ccRCC), (4) Bladder: Urothelial Carcinoma (UC), (5) Skin: Cutaneous Melanoma, excluding Uveal Melanoma, (6)Uterus: endometrial cancer, (7) Colon and Rectum: Microsatellite instability-high (MSIH)\/ deficient mismatch repair (dMMR) Colorectal Cancer (CRC) (8)Liver: Hepatocellular Carcinoma.<br \/>\nPI: Nima Kokabi, MD, FRCPC<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05520099?cond=NCT05520099&amp;limit=10&amp;sort=@relevance&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5318 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-150x150.jpg\" alt=\"Nima Kokabi's headshot. A male with dark brown hair and eyes smiling at the camera. He is wearing a white shirt, bright yellow tie, and dark blue suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>A Prospective, Post-Approval, Open-Label, Multi-Center United States (US) Registry to Evaluate the Effectiveness and Safety of Obsidio in Clinical Practice (OCCLUDE)<\/h3>\n<p>Purpose: To assess effectiveness and safety outcomes of patients who undergo embolization with Obsidio\u2122 Conformable Embolic.<br \/>\nPI: Nima Kokabi, MD, FRCPC<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06170619?cond=NCT06170619&amp;limit=10&amp;sort=@relevance&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5318 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-150x150.jpg\" alt=\"Nima Kokabi's headshot. A male with dark brown hair and eyes smiling at the camera. He is wearing a white shirt, bright yellow tie, and dark blue suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_KokabiNima_Web_230401-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Evaluation of a Simple-Prep Controlled Embolic (GPX Trial)<\/h3>\n<p>Purpose: To evaluate the safety and effectiveness of the GPX\u00ae Embolic Device when used as indicated for embolization requiring distal vessel penetration.<br \/>\nPI: Nima Kokabi, MD, FRCPC<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06453642?cond=NCT06453642&amp;limit=10&amp;sort=@relevance&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5297 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-150x150.jpg\" alt=\"David Mauro headshot. Male with brown hair and eyes is smiling at the camera. He is wearing a white shirt, a black checkered tie, and a white doctor's coat.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>A prospective, multicenter, open-label single arm study evaluating the safety and efficacy of selective internal radiation therapy (SIRT) using SIR-Spheres\u00ae Y-90 resin microspheres on duration of response (DoR) and objective response rate (ORR) in hepatocellular carcinoma (HCC) patients (DOORwaY90 Study)<\/h3>\n<p>Purpose: To evaluate the safety and effectiveness of SIRT using SIR-Spheres Y-90 resin microspheres as first-line treatment for local control of HCC in patients with Barcelona Clinic Liver Cancer (BCLC) stage A, B1, B2, and C.<br \/>\nPI: David Mauro, MD<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04736121?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT04736121&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5297 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-150x150.jpg\" alt=\"David Mauro headshot. Male with brown hair and eyes is smiling at the camera. He is wearing a white shirt, a black checkered tie, and a white doctor's coat.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_MauroDavid_Web_220923-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Efficacy &amp; Safety of LOBOTM Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations (PAVM)<\/h3>\n<p>Purpose:To evaluate both the technical success and efficacy of PAVM embolization using the LOBO\u2122 device.<br \/>\nPI: David Mauro, MD<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06735976?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT06735976&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5302 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-150x150.jpg\" alt=\"Gloria Salazar's headshot. A female with brown hair and eyes is smiling at the camera. She is wearing a white blouse and light blue and white jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_SalazarGloria_Web_220706-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Randomized Controlled, Single-blind, Parallel-Group Trial of Ovarian Vein and Pelvic Vein Embolization in Women with Chronic Pelvic Pain and Pelvic Varices (EMBOLIZE Trial)<\/h3>\n<p>Purpose: To assess whether bilateral ovarian vein embolization (OVE) and pelvic vein embolization (PVE) reduces pain symptoms and improves quality of life in women with pelvic venous disease (PeVD) and chronic pelvic pain (CPP).<br \/>\nPI: Gloria Salazar, MD<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06618300?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT06618300&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5314 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-150x150.jpg\" alt=\"Hyeon Yu's headshot. An Asian male with black hair and brown eyes wearing glasses is looking at the camera. He is wearing a light blue shirt, dark blue tie, and grey suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/VIR_YuHyeon_Web_220923-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Streamlined Resin Y90 Radiation Segmentectomy for Small HCC: One &amp; Done Trial<\/h3>\n<p>Purpose: To evaluate the safety and efficacy of streamlining Yttrium-90 radioembolization workflow for patients with small Hepatocellular Carcinoma (HCC) ( &lt; 5 cm) that have no aggressive features on baseline imaging.<br \/>\nPI: Hyeon yu, MD<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06168058?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT06168058&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\">\n<div class=\"panel-heading oscitas-bootstrap-container\">\n<h2><a id=\"MIT\"><\/a>Molecular Imaging &amp; Therapeutics<\/h2>\n<\/div>\n<\/div>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5253 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg\" alt=\"Jorge Oldan's headshot. Male with brown thinning hair and brown eyes wearing glasses. He is wearing a blue open-collar button-down shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Evaluation of Endometriosis with 18F-fluoroestradiol PET \/ MRI<\/h3>\n<p>The primary objective is to evaluate the sensitivity and specificity of 18F-fluorofuranylnorprogesterone (FFNP) PET\/MR for evaluating endometriosis. Secondary objectives include comparing PET to conventional MRI, using histopathology from laparotomy as the gold standard and evaluating association of uptake values (SUV-max) with EHP-30 and pain rating scales, controlling for covariates.<br \/>\nPI: Jorge Oldan, MD<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04382911?term=NCT04382911&amp;draw=2&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5253 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg\" alt=\"Jorge Oldan's headshot. Male with brown thinning hair and brown eyes wearing glasses. He is wearing a blue open-collar button-down shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>A Phase II Trial to Evaluate Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer<\/h3>\n<p>Purpose: to assess the accuracy of FFNP-PET in predicting response to abemaciclib + endocrine therapy.<br \/>\nPI: Jorge Oldan, MD<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06179303?cond=NCT06179303&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5253 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg\" alt=\"Jorge Oldan's headshot. Male with brown thinning hair and brown eyes wearing glasses. He is wearing a blue open-collar button-down shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Portable Gamma Camera for Evaluation of Therapeutic Radiopharmaceutical Extravasation<\/h3>\n<p>Purpose: to use a portable gamma camera to determine the extravasation rates in patients receiving Radiopharmaceutical therapy.<br \/>\nPI: Jorge Oldan, MD<br \/>\nActive Enrolling<\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5253 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg\" alt=\"Jorge Oldan's headshot. Male with brown thinning hair and brown eyes wearing glasses. He is wearing a blue open-collar button-down shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>P01 Endometriosis Diagnostic and Therapeutic Collaborative Center- Project 1: Diagnosis and Treatment of Endometriosis: A Translational Approach<\/h3>\n<p>Purpose:To determine mechanisms preventing inflammation resolution in women with endometriosis.<br \/>\nPI: Jorge Oldan, MD<br \/>\nActive &#8211; Closed to Enrollment<\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5253 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg\" alt=\"Jorge Oldan's headshot. Male with brown thinning hair and brown eyes wearing glasses. He is wearing a blue open-collar button-down shirt.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/MIT_OldanJorge_Web_220614-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>EA1211: Interim FDG-PET\/CT for PreDIcting Response of HER2+ Breast Cancer to Neoadjuvant Therapy: DIRECT trial<\/h3>\n<p>Purpose: To investigate the performance of FDG-PET\/CT as a predictor of pathologic complete respone (pCR) in patients treated with neoadjuvant HER2-directed therapy.<br \/>\nPI: Jorge Oldan, MD<br \/>\nActive &#8211; Closed to Enrollment<\/p>\n<p>For more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05710328?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT05710328&amp;rank=1\">ClinicalTrials.org<\/a><\/div>\n<\/div>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\">\n<div class=\"panel-heading oscitas-bootstrap-container\">\n<h2><a id=\"neuro\"><\/a>Neuroradiology<\/h2>\n<\/div>\n<\/div>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5281 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-150x150.jpg\" alt=\"Yueh Lee, MD, PhD, headshot. An Asian male with short black hair and brown eyes, wearing glasses, is looking at the camera. He is wearing a white shirt, a pink tie, and a grey suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>High Frame Rate 3-D Super Resolution Ultrasound Microvascular Imaging<\/h3>\n<p>Purpose: This is a 3 arm single-center study of 35 patients scheduled to undergo a breast or thyroid biopsy that consent to undergo an acoustic angiography in conjunction with b-mode ultrasound prior to their scheduled biopsy. Prior to imaging clinical patients, the third arm will include 5 healthy volunteers that will be imaged to optimize imaging parameters. The primary objective of this study is to compare the sensitivity and specificity of super-resolution acoustic angiography with traditional b-mode ultrasound in the distinction of malignant versus benign breast and thyroid lesions. Secondary objectives include a comparison of area under the curve (AUC) for acoustic angiography versus b-mode ultrasound and a comparison of radiologist preference for the two imaging techniques for each of 3 lesion characteristics.<br \/>\nPI: Yeah Lee, MD, PhD<br \/>\nActive &#8211; Closed to Enrollment<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04136912?term=NCT04136912&amp;draw=2&amp;rank=1\">ClinicalTrials.gov<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5281 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-150x150.jpg\" alt=\"Yueh Lee, MD, PhD, headshot. An Asian male with short black hair and brown eyes, wearing glasses, is looking at the camera. He is wearing a white shirt, a pink tie, and a grey suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Academic-Industrial Partnership for Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging<\/h3>\n<p>Purpose:To evaluate the sensitivity and specificity of Contrast Enhanced Super-Resolution (CESR) imaging in the analysis of known breast, liver, and kidney lesions by comparing image analyses to the pathological results for these lesions.<br \/>\nPI: Yeah Lee, MD, PhD<br \/>\nActive &#8211; Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT07225114?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT07225114&amp;rank=1\">ClinicalTrials.gov<\/a><\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5281 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-150x150.jpg\" alt=\"Yueh Lee, MD, PhD, headshot. An Asian male with short black hair and brown eyes, wearing glasses, is looking at the camera. He is wearing a white shirt, a pink tie, and a grey suit jacket.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/NEURO_LeeYueh_Web_0321-e1722004744795-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>EAF223: Phase II Glioblastoma Accelerated Biomarkers Learning Environment Trial (GABLE)<\/h3>\n<p>Purpose:For each biomarker (Dynamic Susceptibility Contrast-Enhanced MR Imaging, 18F-fluciclovine PET, MR Spectroscopy), to evaluate whether the biomarker can stratify patients with newly diagnosed glioblastoma (GBM) that have progressive enhancement within 12 weeks post-XRT into risk groups based on overall survival.<br \/>\nPI: Yeah Lee, MD, PhD<br \/>\nActive &#8211; Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06319027?limit=10&amp;sort=@relevance&amp;locn=Keefe&amp;cond=NCT06319027&amp;rank=1\">ClinicalTrials.gov<\/a><\/div>\n<\/div>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\"><\/div>\n<div class=\"panel-heading oscitas-bootstrap-container\"><\/div>\n<h2><a id=\"peds\"><\/a>Pediatrics<\/h2>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5293 size-thumbnail\" src=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-150x150.jpg\" alt=\"Will Pryor's headshot. A male with light brown hair, a beard, and blue eyes is smiling at the camera. He is wearing a blue and white checkered shirt with a pink bow tie and a white doctor's coat.\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-150x150.jpg 150w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-300x300.jpg 300w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-768x768.jpg 768w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-2048x2048.jpg 2048w, https:\/\/www.med.unc.edu\/radiology\/wp-content\/uploads\/sites\/1384\/2024\/02\/PEDS_PryorWill_Web_220808-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div>\n<div class=\"col-lg-9 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h3>Accuracy of ultrasound for the evaluation of percutaneous gastrostomy tube position and leakage<\/h3>\n<p>Evaluate the accuracy of ultrasound for the evaluation of percutaneous gastrostomy tube positioning following replacement in comparison with fluoroscopic evaluation.<br \/>\nPI: William Pryor, MD<br \/>\nActive Enrolling<br \/>\nFor more information: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06361498?cond=NCT06361498&amp;rank=1\">ClinicalTrials.gov<\/a><\/div>\n<\/div>\n<div class=\"panel panel-primary  oscitas-bootstrap-container\"><\/div>\n<div class=\"panel-heading oscitas-bootstrap-container\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>UNC Radiology clinical and radiological science faculty are engaged in multiple clinical trials. Our studies investigate new approaches to diagnostic radiology and treating diseases and conditions.\u00a0The clinical trials include close collaboration between scientists and physicians from many areas of expertise. All trials are overseen by the Institutional Review Board (IRB) to ensure the highest ethical &hellip; <a href=\"https:\/\/www.med.unc.edu\/radiology\/research\/clinical-research\/clinical-trials\/\" aria-label=\"Read more about Clinical Trials\">Read more<\/a><\/p>\n","protected":false},"author":79967,"featured_media":0,"parent":231,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-237","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Clinical Trials - Department of Radiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/radiology\/research\/clinical-research\/clinical-trials\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical Trials - Department of Radiology\" \/>\n<meta property=\"og:description\" content=\"UNC Radiology clinical and radiological science faculty are engaged in multiple clinical trials. Our studies investigate new approaches to diagnostic radiology and treating diseases and conditions.\u00a0The clinical trials include close collaboration between scientists and physicians from many areas of expertise. 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