Sha Chang (PI), Jian Zhang, Eric Schreiber, Adrienne Cox, David Borldelon*, Otto Zhou*;
*Department of Physics & Astronomy, University of North Carolina at Chapel Hill
We use carbon nanotube field emission technology to develop new irradiation devices to meet the needs of high spatial and temporal resolution yet compact cellular irradiation devices suitable for average biology laboratories. The proposed system promises simultaneous irradiation of many individually selected cells or cellular regions under microscope observation. Recently, we have successfully developed the first prototype device and calibrated its 30keV electron beam Radiation dosimetry. We have validated the prototype system by cell irradiation and observation of the expected DNA damage.