{"id":4065,"date":"2011-02-24T11:45:10","date_gmt":"2011-02-24T16:45:10","guid":{"rendered":"https:\/\/www.med.unc.edu\/radonc\/?p=4065"},"modified":"2020-04-29T15:29:17","modified_gmt":"2020-04-29T19:29:17","slug":"trus-augmented-by-mri-mrsi-for-prostate-interventions","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/","title":{"rendered":"TRUS augmented by MRI\/MRSI for prostate interventions"},"content":{"rendered":"<p class=\"lead\">Goal: merge US with MR to visualize targets for biopsy needles, radioactive seeds and ablation instruments.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2603 size-full\" title=\"TRUS\" src=\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg\" alt=\"TRUS\" width=\"261\" height=\"137\" align=\"right\" srcset=\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg 261w, https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1-150x79.jpg 150w\" sizes=\"auto, (max-width: 261px) 100vw, 261px\" \/>Prostate interventions such as biopsy, brachytherapy, and therapeutic tissue ablation are visually guided by trans-rectal ultrasound images (TRUS). TRUS shows the overall shape of the prostate but does not distinguish cancer from normal prostate tissue. The inability to actually see where cancer is located during a TRUS procedure severely limits the ability of the surgeon to accurately aim his\/her instrument at suspected cancer growths. Due to this limitation current biopsy procedures lead to a relatively high number of undetected cases (false negatives). Moreover brachytherapy and ablation procedures must target volumes of tissue larger than necessary to assure inclusion of the cancer growths in the target region, an approach that can lead to unwanted side effects. Recent research has shown that the combination of magnetic resonance imaging (MRI) and magnetic resonance spectroscopic imaging (MRSI) can pinpoint regions likely to harbor cancer cells inside the prostate. M-reps are being investigated to accurately map potential cancer-bearing regions found on pre-intervention MR\/MRS images to TRUS images, and display those regions as targets for interventional instruments such as biopsy needles, radioactive seeds, and ablation instruments.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Goal: merge US with MR to visualize targets for biopsy needles, radioactive seeds and ablation instruments.<\/p>\n","protected":false},"author":73344,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[67],"tags":[21],"class_list":["post-4065","post","type-post","status-publish","format-standard","hentry","category-projects","tag-image-guided-rt","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>TRUS augmented by MRI\/MRSI for prostate interventions | Department of Radiation Oncology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TRUS augmented by MRI\/MRSI for prostate interventions | Department of Radiation Oncology\" \/>\n<meta property=\"og:description\" content=\"Goal: merge US with MR to visualize targets for biopsy needles, radioactive seeds and ablation instruments.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Radiation Oncology\" \/>\n<meta property=\"article:published_time\" content=\"2011-02-24T16:45:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-04-29T19:29:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg\" \/>\n<meta name=\"author\" content=\"Nick Perisich\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UNCRadOnc\" \/>\n<meta name=\"twitter:site\" content=\"@UNCRadOnc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\"},\"author\":{\"name\":\"Nick Perisich\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/5afbd02e04a64ce4bbbe794a0e1ce216\"},\"headline\":\"TRUS augmented by MRI\/MRSI for prostate interventions\",\"datePublished\":\"2011-02-24T16:45:10+00:00\",\"dateModified\":\"2020-04-29T19:29:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\"},\"wordCount\":206,\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg\",\"keywords\":[\"Image Guided RT\"],\"articleSection\":[\"Projects\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\",\"url\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\",\"name\":\"TRUS augmented by MRI\/MRSI for prostate interventions | Department of Radiation Oncology\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg\",\"datePublished\":\"2011-02-24T16:45:10+00:00\",\"dateModified\":\"2020-04-29T19:29:17+00:00\",\"author\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/5afbd02e04a64ce4bbbe794a0e1ce216\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg\",\"width\":261,\"height\":137},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/radonc\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"TRUS augmented by MRI\/MRSI for prostate interventions\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/radonc\/\",\"name\":\"Department of Radiation Oncology\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/radonc\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/5afbd02e04a64ce4bbbe794a0e1ce216\",\"name\":\"Nick Perisich\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/34b9cd2c2d3e48fb4ff9b0eb08947aee678b8097f23f71641cc6460cbd41b56d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/34b9cd2c2d3e48fb4ff9b0eb08947aee678b8097f23f71641cc6460cbd41b56d?s=96&d=mm&r=g\",\"caption\":\"Nick Perisich\"},\"url\":\"https:\/\/www.med.unc.edu\/radonc\/author\/nickgfp\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"TRUS augmented by MRI\/MRSI for prostate interventions | Department of Radiation Oncology","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/","og_locale":"en_US","og_type":"article","og_title":"TRUS augmented by MRI\/MRSI for prostate interventions | Department of Radiation Oncology","og_description":"Goal: merge US with MR to visualize targets for biopsy needles, radioactive seeds and ablation instruments.","og_url":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/","og_site_name":"Department of Radiation Oncology","article_published_time":"2011-02-24T16:45:10+00:00","article_modified_time":"2020-04-29T19:29:17+00:00","og_image":[{"url":"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg","type":"","width":"","height":""}],"author":"Nick Perisich","twitter_card":"summary_large_image","twitter_creator":"@UNCRadOnc","twitter_site":"@UNCRadOnc","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#article","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/"},"author":{"name":"Nick Perisich","@id":"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/5afbd02e04a64ce4bbbe794a0e1ce216"},"headline":"TRUS augmented by MRI\/MRSI for prostate interventions","datePublished":"2011-02-24T16:45:10+00:00","dateModified":"2020-04-29T19:29:17+00:00","mainEntityOfPage":{"@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/"},"wordCount":206,"image":{"@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg","keywords":["Image Guided RT"],"articleSection":["Projects"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/","url":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/","name":"TRUS augmented by MRI\/MRSI for prostate interventions | Department of Radiation Oncology","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/radonc\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg","datePublished":"2011-02-24T16:45:10+00:00","dateModified":"2020-04-29T19:29:17+00:00","author":{"@id":"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/5afbd02e04a64ce4bbbe794a0e1ce216"},"breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#primaryimage","url":"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg","contentUrl":"https:\/\/www.med.unc.edu\/radonc\/wp-content\/uploads\/sites\/815\/2018\/07\/trus1.jpg","width":261,"height":137},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/radonc\/trus-augmented-by-mri-mrsi-for-prostate-interventions\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/radonc\/"},{"@type":"ListItem","position":2,"name":"TRUS augmented by MRI\/MRSI for prostate interventions"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/radonc\/#website","url":"https:\/\/www.med.unc.edu\/radonc\/","name":"Department of Radiation Oncology","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/radonc\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/5afbd02e04a64ce4bbbe794a0e1ce216","name":"Nick Perisich","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/radonc\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/34b9cd2c2d3e48fb4ff9b0eb08947aee678b8097f23f71641cc6460cbd41b56d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/34b9cd2c2d3e48fb4ff9b0eb08947aee678b8097f23f71641cc6460cbd41b56d?s=96&d=mm&r=g","caption":"Nick Perisich"},"url":"https:\/\/www.med.unc.edu\/radonc\/author\/nickgfp\/"}]}},"featured_image":false,"featured_image_medium":false,"featured_image_medium_large":false,"featured_image_large":false,"featured_image_thumbnail":false,"featured_image_alt":false,"category_details":[{"name":"Projects","link":"https:\/\/www.med.unc.edu\/radonc\/category\/projects\/"}],"tag_details":[{"name":"Image Guided RT","link":"https:\/\/www.med.unc.edu\/radonc\/tag\/image-guided-rt\/"}],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/posts\/4065","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/users\/73344"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/comments?post=4065"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/posts\/4065\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/media?parent=4065"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/categories?post=4065"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/radonc\/wp-json\/wp\/v2\/tags?post=4065"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}