{"id":2453,"date":"2025-05-05T12:06:58","date_gmt":"2025-05-05T16:06:58","guid":{"rendered":"https:\/\/www.med.unc.edu\/rrcf\/?p=2453"},"modified":"2025-05-06T17:26:12","modified_gmt":"2025-05-06T21:26:12","slug":"rcf-pilot-project-awards","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/","title":{"rendered":"RCF Pilot Project Awards"},"content":{"rendered":"<h3><\/h3>\n<p>In May 2024, the Radiation Core Facility received a grant from Sandia National Laboratories and the National Nuclear Security Administration&#8217;s Office of Radiological Security to support research comparing the radiobiological effects of <sup>137<\/sup>Cs irradiators and x-ray irradiators. The <sup>137<\/sup>Cs irradiator has long been used in various radiation-related research studies. However, due to security concerns associated with its radioactive source, there is a growing movement to transition to x-ray irradiators. While several studies have demonstrated the feasibility of this replacement, the radiobiological equivalency between the two radiation sources needs further validation in a wider scope. This grant provides an opportunity for researchers at the University of North Carolina (UNC) to conduct comparative studies evaluating the radiobiological effects of the two radiation sources specifically related to their research focus, either in cells and animal models. The three participating awardees and their respective project titles are listed below.<\/p>\n<table style=\"height: 193px;width: 100%;background-color: #e3e5e6\" border=\"2px solid rgb(0, 0, 0)\" cellpadding=\"5\">\n<tbody>\n<tr style=\"background-color: #d0e3f2\">\n<td style=\"padding: 5px;width: 1154px;border: 2px solid #000000\">\n<h3><strong>Project Title<\/strong><\/h3>\n<\/td>\n<td style=\"padding: 5px;width: 250px;border: 2px solid #000000\">\n<h3><strong>Investigator<\/strong><\/h3>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px;width: 1154px;border: 2px solid #000000\">Determining the number of hematopoietic stem cells that reconstitute the immune system between X-ray and Cs irradiation using genetic barcodes<\/td>\n<td style=\"padding: 5px;width: 250px;border: 2px solid #000000\">Brian Miller, MD, Ph.D.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px;width: 1154px;border: 2px solid #000000\">Comparing Cs irradiation to X-rays in producing apoptotic blebs for use in forming IgG-ICs<\/td>\n<td style=\"padding: 5px;width: 250px;border: 2px solid #000000\">Barbara Vilen, Ph.D.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px;width: 1154px;border: 2px solid #000000\">Evaluation of X-ray irradiation as a replacement for Cs irradiation for preparation of humanized mice<\/td>\n<td style=\"padding: 5px;width: 250px;border: 2px solid #000000\">Martina Kovarova, Ph.D.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2440 alignleft\" src=\"https:\/\/www.med.unc.edu\/rrcf\/wp-content\/uploads\/sites\/1375\/2025\/05\/Sandia.png\" alt=\"Sandia National Laboratories\" width=\"283\" height=\"43\" srcset=\"https:\/\/www.med.unc.edu\/rrcf\/wp-content\/uploads\/sites\/1375\/2025\/05\/Sandia.png 283w, https:\/\/www.med.unc.edu\/rrcf\/wp-content\/uploads\/sites\/1375\/2025\/05\/Sandia-280x43.png 280w\" sizes=\"auto, (max-width: 283px) 100vw, 283px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2439 alignright\" src=\"https:\/\/www.med.unc.edu\/rrcf\/wp-content\/uploads\/sites\/1375\/2025\/05\/ORS.jpg\" alt=\"Office of Radiological Security\" width=\"147\" height=\"36\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In May 2024, the Radiation Core Facility received a grant from Sandia National Laboratories and the National Nuclear Security Administration&#8217;s Office of Radiological Security to support research comparing the radiobiological effects of 137Cs irradiators and x-ray irradiators. The 137Cs irradiator has long been used in various radiation-related research studies. However, due to security concerns associated &hellip; <a href=\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\" aria-label=\"Read more about RCF Pilot Project Awards\">Read more<\/a><\/p>\n","protected":false},"author":2532,"featured_media":2482,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2453","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>RCF Pilot Project Awards - Research Radiation Core Facility<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RCF Pilot Project Awards - Research Radiation Core Facility\" \/>\n<meta property=\"og:description\" content=\"In May 2024, the Radiation Core Facility received a grant from Sandia National Laboratories and the National Nuclear Security Administration&#8217;s Office of Radiological Security to support research comparing the radiobiological effects of 137Cs irradiators and x-ray irradiators. The 137Cs irradiator has long been used in various radiation-related research studies. However, due to security concerns associated &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\" \/>\n<meta property=\"og:site_name\" content=\"Research Radiation Core Facility\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-05T16:06:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-06T21:26:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/rrcf\/wp-content\/uploads\/sites\/1375\/2025\/05\/sandia-ors-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"227\" \/>\n\t<meta property=\"og:image:height\" content=\"83\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Eric Livingston\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Eric Livingston\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\"},\"author\":{\"name\":\"Eric Livingston\",\"@id\":\"https:\/\/www.med.unc.edu\/rrcf\/#\/schema\/person\/1f675a5bb39c5b191b4205743d2f9850\"},\"headline\":\"RCF Pilot Project Awards\",\"datePublished\":\"2025-05-05T16:06:58+00:00\",\"dateModified\":\"2025-05-06T21:26:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\"},\"wordCount\":215,\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/rrcf\/wp-content\/uploads\/sites\/1375\/2025\/05\/sandia-ors-1.png\",\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\",\"url\":\"https:\/\/www.med.unc.edu\/rrcf\/2025\/05\/rcf-pilot-project-awards\/\",\"name\":\"RCF Pilot Project Awards - 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