{"id":2340,"date":"2025-09-09T23:47:54","date_gmt":"2025-09-10T03:47:54","guid":{"rendered":"https:\/\/www.med.unc.edu\/shire\/?page_id=2340"},"modified":"2026-03-20T12:52:04","modified_gmt":"2026-03-20T16:52:04","slug":"faq","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/shire\/get-help\/faq\/","title":{"rendered":"Frequently Asked Questions"},"content":{"rendered":"<p style=\"text-align: left\"><div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-3 col-md-3 col-xs-12 col-sm-3 oscitas-bootstrap-container\">\n<a href=\"#GenQ\">General Questions<\/a><\/div>\n<div class=\"col-lg-3 col-md-3 col-xs-12 col-sm-3 oscitas-bootstrap-container\">\n<a href=\"#UserAcc\">User Account Questions<\/a><\/div>\n<div class=\"col-lg-3 col-md-3 col-xs-12 col-sm-3 oscitas-bootstrap-container\">\n<a href=\"#TechQ\">Technical Questions<\/a><\/div>\n<div class=\"col-lg-3 col-md-3 col-xs-12 col-sm-3 oscitas-bootstrap-container\">\n<a href=\"#BillQ\">Billing Questions<\/a><\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<h2><strong><a id=\"GenQ\"><\/a>General Questions<\/strong><\/h2>\n<div role=\"tablist\" class=\"panel-group accordion-clean accordion-white oscitas-bootstrap-container\" id=\"unc-accordion-0\">\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-0-0\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-0-0\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-0\"    \n                aria-controls=\"#details-0-0\"  \n                aria-expanded=\"false\" \n                href=\"#details-0-0\">\n                Do you have boilerplate language about the SHIRE that I can use in my grant applications to describe the environment?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-0-0\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Yes! &#8211; <span class=\"TextRun SCXW114782230 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW114782230 BCX0\">\u201cThe Secure Health Informatics Research Environment (SHIRE) is a HIPAA-compliant, secure cloud computing platform hosted by UNC Health that provides flexible compute and analytical tools for data-driven research projects. Data are\u00a0<\/span><span class=\"NormalTextRun SCXW114782230 BCX0\">retained<\/span><span class=\"NormalTextRun SCXW114782230 BCX0\">\u00a0in project-specific workspaces with controlled access.\u00a0<\/span><span class=\"NormalTextRun SCXW114782230 BCX0\">Firewall<\/span><span class=\"NormalTextRun SCXW114782230 BCX0\">\u00a0rules are set to prevent any data\u00a0<\/span><span class=\"NormalTextRun SCXW114782230 BCX0\">exfiltratio<\/span><span class=\"NormalTextRun SCXW114782230 BCX0\">n unless explicitly allowed.\u201d<\/span><\/span><\/li>\n<li><span class=\"NormalTextRun SCXW114782230 BCX0\">If you need more detail, you may want to reference the\u00a0<\/span><span class=\"NormalTextRun CommentStart CommentHighlightPipeRest CommentHighlightRest SCXW114782230 BCX0\">SHIRE Fact Sheet<\/span><span class=\"NormalTextRun CommentHighlightPipeRest SCXW114782230 BCX0\">.<\/span><\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<h2><strong><a id=\"UserAcc\"><\/a>User Account Questions<\/strong><\/h2>\n<div role=\"tablist\" class=\"panel-group accordion-clean accordion-white oscitas-bootstrap-container\" id=\"unc-accordion-1\">\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-1-0\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-1-0\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-1\"    \n                aria-controls=\"#details-1-0\"  \n                aria-expanded=\"false\" \n                href=\"#details-1-0\">\n                Can I add additional users to my SHIRE workspace?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-1-0\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li><span class=\"TextRun SCXW185846065 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW185846065 BCX0\">Yes. You can add <\/span><span class=\"NormalTextRun SCXW185846065 BCX0\">additional<\/span><span class=\"NormalTextRun SCXW185846065 BCX0\">\u00a0IRB-approved users by\u00a0<\/span><span class=\"NormalTextRun SCXW185846065 BCX0\">submitting<\/span>\u00a0<\/span><a class=\"Hyperlink SCXW185846065 BCX0\" href=\"https:\/\/wkf.ms\/4oSz1FD\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Underlined SCXW185846065 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW185846065 BCX0\" data-ccp-charstyle=\"Hyperlink\">this form<\/span><\/span><\/a><span class=\"TextRun SCXW185846065 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW185846065 BCX0\"> at any time<\/span><\/span>.<\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-1-1\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-1-1\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-1\"    \n                aria-controls=\"#details-1-1\"  \n                aria-expanded=\"false\" \n                href=\"#details-1-1\">\n                How can I remove a user from my SHIRE workspace?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-1-1\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li><span class=\"TextRun SCXW185846065 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW185846065 BCX0\">You can remove a user by by <\/span><span class=\"NormalTextRun SCXW185846065 BCX0\">submitting<\/span>\u00a0<\/span><a class=\"Hyperlink SCXW185846065 BCX0\" href=\"https:\/\/wkf.ms\/4oSz1FD\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Underlined SCXW185846065 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW185846065 BCX0\" data-ccp-charstyle=\"Hyperlink\">this form<\/span><\/span><\/a>. Prior to submitting this form, you should (1.) ensure the user&#8217;s VMs do not have any key data or code and (2.) ensure all of the user&#8217;s VMs have been deactivated.<br \/>\n<\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-1-2\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-1-2\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-1\"    \n                aria-controls=\"#details-1-2\"  \n                aria-expanded=\"false\" \n                href=\"#details-1-2\">\n                I am getting e-mail reminders for UNC Health LMS training requirements. Do I have to do them?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-1-2\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li><span class=\"TextRun SCXW6136573 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW6136573 BCX0\">Yes\u2014these trainings are\u00a0<\/span><span class=\"NormalTextRun SCXW6136573 BCX0\">required<\/span><span class=\"NormalTextRun SCXW6136573 BCX0\">\u00a0as part of having UNC Health login credentials.<\/span><\/span> <\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<h2><strong><a id=\"TechQ\"><\/a>Technical Questions<\/strong><\/h2>\n<div role=\"tablist\" class=\"panel-group accordion-clean accordion-white oscitas-bootstrap-container\" id=\"unc-accordion-2\">\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-2-0\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-2-0\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-2\"    \n                aria-controls=\"#details-2-0\"  \n                aria-expanded=\"false\" \n                href=\"#details-2-0\">\n                What software is not supported on the SHIRE?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-2-0\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>We are happy to review any user requests for software to be added to <span class=\"NormalTextRun SCXW152246661 BCX0\">the SHIRE<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">, using our\u00a0<\/span><a style=\"background-color: #ffffff\" href=\"https:\/\/unchc.service-now.com\/sp?id=sc_cat_item&amp;sys_id=261bba6487da6a14a4a574c9cebb35e5\"><span class=\"NormalTextRun CommentStart CommentHighlightPipeRest CommentHighlightRest SCXW152246661 BCX0\">software request form<\/span><\/a><span class=\"NormalTextRun CommentHighlightPipeRest SCXW152246661 BCX0\">. However, licensed software for which we do not have\u00a0<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">an ins<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">titutional license may be difficult for us<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\"> to support.<\/span>\n<ul>\n<li><span class=\"NormalTextRun SCXW152246661 BCX0\">For example, Microsoft Office products and SAS are licensed software for which UNC has an institutional license\u00a0<\/span><span class=\"TextRun SCXW152246661 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW152246661 BCX0\">we are able to support th<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">em\u00a0<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">in\u00a0<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">the SHIRE<\/span><span class=\"NormalTextRun SCXW152246661 BCX0\">.<\/span><\/span><\/li>\n<li>On the other hand, STATA and SPSS are licensed software for which UNC does NOT have an institutional license.<span class=\"NormalTextRun SCXW152246661 BCX0\">\u00a0We do\u00a0<strong>NOT<\/strong>\u00a0currently have a way to support those tools.<\/span><\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-2-1\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-2-1\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-2\"    \n                aria-controls=\"#details-2-1\"  \n                aria-expanded=\"false\" \n                href=\"#details-2-1\">\n                I trained a machine learning model on data inside of the SHIRE. Can I extract the trained model file?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-2-1\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li><span class=\"TextRun SCXW218356490 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW218356490 BCX0\">Likely yes<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">, but it depends on a few factors. If yo<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">u <\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">received de-identified data from the CDWH and trained your model on those data<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">, <\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">you <\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">can<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> request<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> extraction of the model file as a Type 1 export\u2014see <\/span><\/span><a class=\"Hyperlink SCXW218356490 BCX0\" href=\"https:\/\/www.med.unc.edu\/shire\/wp-content\/uploads\/sites\/1472\/2025\/11\/Requesting-a-Data-Export-from-SHIRE.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Underlined SCXW218356490 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW218356490 BCX0\" data-ccp-charstyle=\"Hyperlink\">our Export request documentation<\/span><\/span><\/a><span class=\"TextRun SCXW218356490 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW218356490 BCX0\"> for more details. <\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">If you <\/span><span class=\"NormalTextRun ContextualSpellingAndGrammarErrorV2Themed SCXW218356490 BCX0\">trained<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> your model on HIPAA-limited or <\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">identified<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> data,<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> you may still be able to export the trained model if you are able to prove you have taken steps to prevent identifiers from leaking into the model (by, for example, de-identifying the dataset). Requests to export models for HIPAA-limited or <\/span><span class=\"NormalTextRun SCXW218356490 BCX0\">identified<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> data requests need approval by the CDWH Operations Committee. To request approval, please contact the <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW218356490 BCX0\">TraCS<\/span><span class=\"NormalTextRun SCXW218356490 BCX0\"> analyst or PM you worked with.<\/div>\n\n    <\/div>\n        \n<\/div><\/span><\/span><span class=\"EOP SCXW218356490 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<\/ul>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-2-2\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-2-2\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-2\"    \n                aria-controls=\"#details-2-2\"  \n                aria-expanded=\"false\" \n                href=\"#details-2-2\">\n                I got an e-mail saying my virtual machine in Azure DevTest Labs will automatically shut down. What does that mean?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-2-2\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li><span class=\"NormalTextRun SCXW160622168 BCX0\">The SHIRE automatically shuts down all Virtual Machines (VMs) at 7:00 PM Eastern Standard Time each night unless you specifically \u201csnooze\u201d or cancel the shutdown via the links in that email. The auto-shutdown is in place to prevent users from accidentally leaving VMs on perpetually and running up unintended charges.<\/span><\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-2-3\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-2-3\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-2\"    \n                aria-controls=\"#details-2-3\"  \n                aria-expanded=\"false\" \n                href=\"#details-2-3\">\n                Is there a way to estimate how much it will cost to use a large language model (LLM) in the SHIRE?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-2-3\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li>Members of the SHIRE team have <a href=\"https:\/\/www.med.unc.edu\/shire\/get-help\/cost-scenarios-for-large-language-models-in-the-shire\/\">modeled several different parameters<\/a> surrounding LLM utilization to assist users in budgeting and cost estimation. This modeling may allow researchers to better estimate their anticipated costs based on a variety of factors. However, users should know that it is impossible to fully predict cost of LLM usage with more than moderate precision.<\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<h2><strong><a id=\"BillQ\"><\/a>Billing Questions<\/strong><\/h2>\n<div role=\"tablist\" class=\"panel-group accordion-clean accordion-white oscitas-bootstrap-container\" id=\"unc-accordion-3\">\n\n<div class=\"panel panel-default oscitas-bootstrap-container\">\n\n    <div id=\"panel-heading-details-3-0\" class=\"panel-heading oscitas-bootstrap-container\" role=\"tab\">\n\n        <h3 class=\"panel-title oscitas-bootstrap-container\">\n\n            <button class=\"accordion-toggle oscitas-bootstrap-container collapsed\" \n                id = \"button-details-3-0\"\n                data-toggle=\"collapse\"\n                data-parent=\"#unc-accordion-3\"    \n                aria-controls=\"#details-3-0\"  \n                aria-expanded=\"false\" \n                href=\"#details-3-0\">\n                Can you help me understand the line items on my weekly cost report?            <\/button>\n\n        <\/h3>\n\n    <\/div>\n\n    <div id=\"details-3-0\" class=\"panel-collapse collapse  oscitas-bootstrap-container\">\n\n        <div class=\"panel-body oscitas-bootstrap-container\">\n<ul>\n<li><span class=\"TextRun SCXW185846065 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW185846065 BCX0\">Yes. Please reference the <a href=\"https:\/\/www.med.unc.edu\/shire\/get-help\/quick-billing-model-guide\/\">Quick Billing Model Guid<\/a>e to learn more about the line items that may appear on your weekly cost report.<\/span><\/span><\/div>\n\n    <\/div>\n        \n<\/div><\/li>\n<\/ul>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; General Questions User Account Questions Technical Questions Billing Questions<\/p>\n","protected":false},"author":55643,"featured_media":0,"parent":2307,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2340","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Frequently Asked Questions - The SHIRE Platform<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/shire\/get-help\/faq\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Frequently Asked Questions - The SHIRE Platform\" \/>\n<meta property=\"og:description\" content=\"&nbsp; 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