{"id":10067,"date":"2019-07-30T13:37:59","date_gmt":"2019-07-30T17:37:59","guid":{"rendered":"https:\/\/www.med.unc.edu\/surgery\/?p=10067"},"modified":"2019-08-09T16:09:58","modified_gmt":"2019-08-09T20:09:58","slug":"first-patient-receives-surgery-in-unc-led-international-pivotal-trial-for-repair-of-thoracoabdominal-and-pararenal-aortic-aneurysms","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/surgery\/first-patient-receives-surgery-in-unc-led-international-pivotal-trial-for-repair-of-thoracoabdominal-and-pararenal-aortic-aneurysms\/","title":{"rendered":"First Patient Receives Surgery in UNC-Led International Pivotal Trial for Repair of Thoracoabdominal and Pararenal Aortic Aneurysms"},"content":{"rendered":"<p class=\"lead\">Mark Farber, MD, chief of vascular surgery at the UNC School of Medicine, is the national principal investigator for the study and performed the trial\u2019s first implant of the GORE\u00ae EXCLUDER\u00ae Thoracoabdominal Branch Endoprosthesis, an investigational device, at UNC Hospitals in Chapel Hill, NC.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-10042\" src=\"https:\/\/www.med.unc.edu\/surgery\/wp-content\/uploads\/sites\/854\/2019\/07\/VascularSurgery-300x200.jpg\" alt=\"\" width=\"300\" height=\"200\" srcset=\"https:\/\/www.med.unc.edu\/surgery\/wp-content\/uploads\/sites\/854\/2019\/07\/VascularSurgery-300x200.jpg 300w, https:\/\/www.med.unc.edu\/surgery\/wp-content\/uploads\/sites\/854\/2019\/07\/VascularSurgery-768x512.jpg 768w, https:\/\/www.med.unc.edu\/surgery\/wp-content\/uploads\/sites\/854\/2019\/07\/VascularSurgery-1024x683.jpg 1024w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>CHAPEL HILL, NC \u2013 The pivotal trial to determine the safety and effectiveness of a modular device designed to be the first completely off-the-shelf endovascular solution for aortic aneurysms involving the visceral branch vessels is successfully underway with its first surgery at UNC Hospitals in Chapel Hill, NC.<\/p>\n<p><a href=\"https:\/\/www.med.unc.edu\/surgery\/vasc\/directory\/mark-a-farber-md\/\">Mark Farber, MD<\/a>, chief of vascular surgery at the UNC School of Medicine, is the national principal investigator of the study which is being conducted to obtain approval of the device from the U.S. Food and Drug Administration (FDA). The device \u2013 the GORE\u00ae EXCLUDER\u00ae Thoracoabdominal Branch Endoprosthesis (TAMBE) \u2013 is manufactured by W. L. Gore &amp; Associates, Inc.<\/p>\n<p>Farber performed the trial\u2019s first implant on July 8, 2019, using the endovascular device to repair a Crawford type IV thoracoabdominal aortic aneurysm which involved blood vessels supplying the kidneys, liver, stomach and intestines. The TAMBE device allows patients to avoid the traditional open surgical approach and utilizes a less invasive endovascular approach to repair the aneurysm. While thoracoabdominal aortic aneurysms constitute a low percentage of aortic aneurysms, the involvement of multiple vessels supplying the kidneys and visceral organs makes their repair one of the more challenging tasks in aortic surgery.<\/p>\n<p>\u201cEndovascular repair of thoracoabdominal aneurysms with appropriate devices is limited in the U.S. to a handful of centers,\u201d Farber said. \u201cIn most instances, the patients must wait several weeks for a custom manufactured device designed specifically for their individual anatomy. This makes it difficult to quickly treat these aneurysms, which are often life-threatening. New technology like the investigational Gore TAMBE device allows for expeditious repair while avoiding some of the risks associated with open surgical repair.\u201d<\/p>\n<p>\u201cToday marks important progress in our ability to provide patients with an advanced technological option for the treatment of thoracoabdominal and pararenal aortic aneurysms,\u201d said Eric Zacharias, a vascular business leader at Gore. \u201cResults from this pivotal study could help in obtaining approval from the FDA for this innovative solution to better address challenging aortic anatomies and provide physicians with an even more complete device portfolio for the treatment of aortic aneurysms.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mark Farber, MD, chief of vascular surgery at the UNC School of Medicine, is the national principal investigator for the study and performed the trial\u2019s first implant of the GORE\u00ae EXCLUDER\u00ae Thoracoabdominal Branch Endoprosthesis, an investigational device, at UNC Hospitals in Chapel Hill, NC.<\/p>\n","protected":false},"author":83776,"featured_media":3597,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[66,28,5,68,67],"featured-item":[],"class_list":["post-10067","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-chapel-hill","tag-news","tag-unc-department-of-surgery","tag-unc-school-of-medicine","tag-vascular-surgery","odd"],"pp_force_visibility":null,"pp_subpost_visibility":null,"pp_inherited_force_visibility":null,"pp_inherited_subpost_visibility":null,"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>First Patient Receives Surgery in UNC-Led 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