Dr. Liu’s Lab
Peng Liu, MD, PhD
The primary goal of Dr. Liu’s research is to investigate the immune mechanisms by which myeloid cells drive inflammation that causes tissue damage in RA and atherosclerosis.
Dr. Liu’s research is grounded in the belief that obtaining a more in-depth understanding of myeloid cell function and its immune networking in RA and coronary heart disease will lead to new therapies as well as prevention strategies against joint damage and life-threatening cardiac events.
Her lab uses genomic, cellular, and molecular approaches to study myeloid cell differentiation, migration, and function in response to autoimmune and metabolic stimuli in mouse disease models, primary cells and tissues, and cell lines. One of the lab’s major projects involves studying the differential transcriptional control, chemotaxis, cell fate, and impact on T and B cells of the monocyte subsets in autoimmune arthritis. The lab is also interested in how myeloid-derived suppressor cells (MDSCs) regulate autoimmune-driven innate and adaptive responses and tissue inflammation.
Another research focus for the lab is determining the contribution of macrophages and dendritic cells to the initiation and development of atherosclerosis. Beside lipid dysfunction and aging, Dr. Liu’s team has made progress in better understanding the link between RA and atherosclerosis.
Dr. Liu’s lab is accepting post-doc applications. If you are interested, please contact Dr. Liu at email@example.com.