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PRODID:-//Thurston Arthritis Research Center - ECPv6.15.18//NONSGML v1.0//EN
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METHOD:PUBLISH
X-ORIGINAL-URL:https://www.med.unc.edu/tarc
X-WR-CALDESC:Events for Thurston Arthritis Research Center
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20230217T120000
DTEND;TZID=America/New_York:20230217T130000
DTSTAMP:20260422T233526
CREATED:20230208T154646Z
LAST-MODIFIED:20230216T214131Z
UID:10000705-1676635200-1676638800@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Ming-Feng Hsueh; "Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis"
DESCRIPTION:“Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis” \nBrief Description: Through the novel use of in vivo protein deamidation molecular clocks\, we unmasked a position-dependent gradient of protein anabolism in human lower limb cartilages. This gradient is strikingly associated with the expression of evolutionarily-conserved limb-regenerative miRNAs. This association shows a potential link to a capacity for regeneration that might be exploited to enhance joint repair. \nDr. Ming-Feng Hsueh\, Assistant Professor\nDepartment of or of Orthopedic surgery\nDuke University \nAttend in TARC Dickson Conference room\, or remotely. \nJoin Zoom Meeting https://zoom.us/j/97766513682?pwd=ck1OZVNnRFdNNmFHc3gyaUU3TmxDdz09 \nMeeting ID: 977 6651 3682\nPasscode: 432508\nOne tap mobile\n+13017158592\,\,97766513682#\,\,\,\,*432508# US (Washington DC)\n+13052241968\,\,97766513682#\,\,\,\,*432508# US \n 
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-ming-feng-hsueh-novel-mechanisms-of-microrna-mediated-anabolic-effects-in-osteoarthritis/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20230127T120000
DTEND;TZID=America/New_York:20230127T130000
DTSTAMP:20260422T233526
CREATED:20221212T185015Z
LAST-MODIFIED:20230112T220313Z
UID:10000700-1674820800-1674824400@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Anne-Marie Malfait; "Neuroplasticity in the knee joint: More than just pain."
DESCRIPTION:“Neuroplasticity in the knee joint: More than just pain.” \nBrief Description: I will describe the sensory innervation of the joint\, its anatomical and molecular properties\, and how these properties change in the course of osteoarthritis (=neuroplasticity). I will discuss the biological role of this neuroplasticity in pain and in joint homeostasis. \nAnne-Marie Malfait\, MD\, PhD \nFaculty\, Rush University \nAttend Live in TARC’s Dickson Conference Room\, or via Zoom: https://zoom.us/j/93372731262?pwd=MVJuNVhKaEZOSVU4c29DM2xiaEVQdz09 \nMeeting ID: 933 7273 1262\nPasscode: 667566\nOne tap mobile\n+13017158592\,\,93372731262#\,\,\,\,*667566# US (Washington DC)\n+13052241968\,\,93372731262#\,\,\,\,*667566# US \n  \n  \n  \n  \n 
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-anne-marie-malfait-title-of-presentation-to-be-announced/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20230113T083000
DTEND;TZID=America/New_York:20230113T093000
DTSTAMP:20260422T233526
CREATED:20230109T153043Z
LAST-MODIFIED:20230112T164220Z
UID:10000677-1673598600-1673602200@www.med.unc.edu
SUMMARY:Rheumatology\, Allergy & Immunology Grand Rounds: Dr. Terrence Holt; "Is Narrative Medicine?"
DESCRIPTION:Dr. Terrence Holt \nAssistant Professor of Social Medicine and Internal Medicine \nDivision of Geriatric Medicine\, UNC \n*VIRTUAL ATTENDANCE ONLY FOR THIS PRESENTATION*  \nJoin Zoom Meeting https://zoom.us/j/93369235083?pwd=TU9GQ2dsMitLVk96VjZSV3N4OHpYdz09 \nMeeting ID: 933 6923 5083 \nPasscode: 363826 \nOne tap mobile \n+13126266799\,\,93369235083#\,\,\,\,*363826# US (Chicago) \n+16465588656\,\,93369235083#\,\,\,\,*363826# US (New York) \nThis activity has been planned and implemented under the sole supervision of the Course Directors\, Millie Kwan\, MD\, and Alfredo Rivadeneira\, MD\, in association with the UNC Office of Continuing Professional Development (CPD). The course director and CPD staff have no relevant financial relationships with ineligible companies as defined by the ACCME.  \n  \n 
URL:https://www.med.unc.edu/tarc/event/rheumatology-allergy-immunology-grand-rounds-dr-terrence-holt-is-narrative-medicine/
LOCATION:Remote or In Person Options Available
CATEGORIES:Rheumatology, Allergy and Immunology Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20221216T120000
DTEND;TZID=America/New_York:20221216T130000
DTSTAMP:20260422T233526
CREATED:20220812T200036Z
LAST-MODIFIED:20221212T190929Z
UID:10000583-1671192000-1671195600@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Brian Diekman; "DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.”
DESCRIPTION:“DNA damage and cellular senescence in osteoarthritis pathophysiology.” \nBrief Description: Aging is the largest risk factor for osteoarthritis\, but the mechanisms responsible for this relationship are unclear. Damaged cells can convert to a phenotypic state known as cellular senescence\, and senescent cells are associated with compromised tissue function. This talk will focus on our efforts to understand the accumulation of DNA damage in chondrocytes during aging\, and to assess whether the activation of more efficient DNA damage repair has promise as a strategy to limit cellular senescence and osteoarthritis. \nDr. Brian Diekman\nAssistant Professor of Biomedical Engineering\nUNC-CH & NC State Joint Department of BME \nAttend Live in TARC Dickson Conference Room\, or via Zoom: https://zoom.us/j/97841158212?pwd=MTRpRXVUbHJNY1AzTmRuS1lLWjM1QT09 \nMeeting ID: 978 4115 8212\nPasscode: 922015\nOne tap mobile:\n+13017158592\,\,97841158212#\,\,\,\,*922015# US (Washington DC)\n+13052241968\,\,97841158212#\,\,\,\,*922015# US \n  \n 
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-brian-diekman-title-of-presentation-to-be-announced-soon/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20221118T120000
DTEND;TZID=America/New_York:20221118T130000
DTSTAMP:20260422T233526
CREATED:20220812T195537Z
LAST-MODIFIED:20221024T164510Z
UID:10000581-1668772800-1668776400@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Janet Rubin; "The Skeleton in a Physical World"
DESCRIPTION:“The Skeleton in a Physical World” \nBrief Description: All organisms exist within a physical space and respond to physical forces as part of daily life. The skeleton responds in real-time to physical stresses placed on it to ensure that its structure supports its function. I will discuss how those cells responsible for remodeling skeletal structure respond to mechanical force (load magnitude\, frequency\, and cyclicity)\, and how force rearranges cellular structure in turn. Next I will discuss how maturation into cells that remodel bone is affected by mechanical force and the cell’s cytoskeleton. I will also consider how this information applies to a prescriptive for intelligent exercise. \nDr. Janet Rubin\nSarah Graham Kenan Distinguished Professor of\nMedicine\, Division of Endocrinology and Metabolism\nVice Chair for Research\, Department of Medicine\nUniversity of North Carolina at Chapel Hill \nAttend Live in TARC Dickson Conference Room\, or via Zoom: https://zoom.us/j/99184257365?pwd=Sk12ZDVON3NpSlZydjl5RTdHRlVidz09 \nMeeting ID: 921 0198 5767\nPasscode: 005755\nPhone (New York): 929-205-6099\nPhone (Toll-free): 888-475-4499 \n  \n  \n  \n 
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-janet-rubin-title-of-presentation-to-be-announced-soon/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20221014T080000
DTEND;TZID=America/New_York:20221014T143000
DTSTAMP:20260422T233526
CREATED:20220809T204558Z
LAST-MODIFIED:20220930T160058Z
UID:10000575-1665734400-1665757800@www.med.unc.edu
SUMMARY:Annual "TARC Research Day\," Being Held In-Person\, With Remote Options
DESCRIPTION:After two years of meeting virtually\, we are excited to once again host Research Day 2022 in person.*\n*(In-person attendance pending potential changes in University policies due to COVID-19.) \nAll presenters will host their sessions in person. For certain events there will be a virtual/Zoom option\, for attendees unable to attend in person. \nBe sure to check our TARC Research Day website page frequently for additional details \n and forthcoming updates\, including the Research Day Agenda. \n\nFriday\, October 14th\, 2022\n8:00 a.m. — 2:30 p.m.\nUNC Friday Center\, 100 Friday Center Drive\, Chapel Hill\, N.C.\n \n  \n  \n 
URL:https://www.med.unc.edu/tarc/event/annual-tarc-research-day-in-person-with-remote-options-october-14th/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Day
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220916T120000
DTEND;TZID=America/New_York:20220916T130000
DTSTAMP:20260422T233526
CREATED:20220812T194654Z
LAST-MODIFIED:20220908T182540Z
UID:10000579-1663329600-1663333200@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Laurie Goodrich; "Orthopedic Translational Medicine: Horses\, Humans and the Pursuit of Joint Health"
DESCRIPTION:Presentation Title: “Orthopedic Translational Medicine: Horses\, Humans and the Pursuit of Joint Health” \nBrief description: Post-traumatic Osteoarthritis (PTOA) is extremely common in equine athletes as well as humans. The horse is an incredible translational model and has been utilized for decades to inform equine clinicians treating their patients and MD’s treating people with PTOA. Further\, septic arthritis has been a musculoskeletal condition that causes intense pain\, suffering and sometimes death in both horses and people. This talk will review preclinical modeling to treat PTOA and septic OA in horses as a method to better treat disease in equine patients and humans. Expansive knowledge has been gained in the last decade to further help these common diseases in athletes and this talk will inform attendees of the exciting new modalities that are on the horizon in One Health. \nPresenter:\nLaurie R. Goodrich\, DVM\, MS\, PhD\nDiplomate\, American College of Veterinary Surgeons\nACVS Founding Fellow in Minimally Invasive Surgery\, Large Animal Orthopedics\nBarbara Cox Anthony University Chair in Orthopaedics\nDirector | Orthopaedic Research Center\nProfessor\, Equine Surgery and Lameness\nColorado State University\, College of Veterinary Medicine \nLocation: Dickson Conference Room (3200 Thurston) or attend remotely via Zoom. \nZoom Link and Information: https://zoom.us/j/95258809636?pwd=WXB2VDBvcFhJZU1reWp0TzNqU1BHdz09 \nMeeting ID: 952 5880 9636\nPasscode: 039314 \n\n\nPhone Number (Toll-free): 833-548-0276
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-laurie-goodrich-title-of-presentation-to-be-announced-soon/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220520T120000
DTEND;TZID=America/New_York:20220520T130000
DTSTAMP:20260422T233526
CREATED:20210719T224239Z
LAST-MODIFIED:20220728T173410Z
UID:10000530-1653048000-1653051600@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Doug Phanstiel; "Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis"
DESCRIPTION:“Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis” \nGenome-wide association studies (GWAS) have identified over 100 osteoarthritis (OA)-associated loci; however\, translating these broad loci into actionable therapeutic targets requires identifying the causal variants\, the gene(s) they affect\, and their mechanistic impact on OA risk. We apply genomic\, bioinformatics\, and genome editing approaches to identify novel OA risk genes for further study and therapeutic development. \nDr. Doug Phanstiel \nAssistant Professor of Cell Biology & Physiology \nUNC Chapel Hill \nAttend Live in TARC Dickson Conference Room\, or via Zoom \n\n\n\nVirtual (Zoom) URL: https://zoom.us/j/92101985767?pwd=d3hHbWhHMFlQSm05RmdCVVVmMkVIUT09 \nMeeting ID: 921 0198 5767 \nPasscode: 005755 \nPhone (New York): 929-205-6099 \nPhone (Toll-free): 888-475-4499
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220429T120000
DTEND;TZID=America/New_York:20220429T130000
DTSTAMP:20260422T233526
CREATED:20211108T183112Z
LAST-MODIFIED:20220429T152356Z
UID:10000656-1651233600-1651237200@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Raghunatha Yammani; "Proteostasis: Does it have a role in osteoarthritis?"
DESCRIPTION:Proteostasis: Does it have a role in osteoarthritis? \nBrief description: Loss of proteostasis is one of the hallmarks of aging. We found that aging reduces the expression of molecular chaperones in chondrocytes resulting in cellular stress and inflammation\, which could contribute to the development of osteoarthritis. \nDr. Raghunatha Yammani \nAssociate Professor\, Molecular Medicine \nWake Forest School of Medicine \nAttendance is Hybrid: Dickson Conference Room or Zoom. For in-person attendance\, lunch is provided! \nURL: https://zoom.us/meeting/register/tJMvc-muqT0qHdwYsrzoW03dg8JUwfhkWlFK \nMeeting ID: 972 4067 6078 \nPasscode: 283535 \nPhone (New York): 646 558 8656 \nPhone (Toll-free): 888 475 4499
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-raghunatha-yammani-topic-to-be-announced/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220218T120000
DTEND;TZID=America/New_York:20220218T130000
DTSTAMP:20260422T233526
CREATED:20210719T222917Z
LAST-MODIFIED:20220125T193258Z
UID:10000526-1645185600-1645189200@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Lauren Schnabel; "A new approach to infectious arthritis: understanding bacterial behavior in synovial fluid and developing a novel therapeutic"
DESCRIPTION:“A new approach to infectious arthritis: understanding bacterial behavior in synovial fluid and developing a novel therapeutic” \nBrief Description: This seminar will highlight our group’s work on how and why bacteria form free-floating biofilms in synovial fluid including our ex-vivo model system. The seminar will then focus on our development of a novel therapeutic\, BIO-PLY\, for the treatment of Staphylococcus aureus infectious arthritis and its demonstrated efficacy both ex-vivo and in-vivo in an equine model. Lastly\, data from clinical cases of infectious arthritis treated with BIO-PLY at NC State CVM Equine Hospital will be presented. \nLauren Schnabel\, DVM\, PhD \nAssistant Professor \nN.C. State University \n\n\n\nVirtual (Zoom) \nURL: https://zoom.us/j/92101985767?pwd=d3hHbWhHMFlQSm05RmdCVVVmMkVIUT09 \nMeeting ID: 921 0198 5767 \nPasscode: 005755 \nPhone (New York): 929-205-6099 \nPhone (Toll-free): 888-475-4499\n\n\n\n 
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-dr-lauren-schnabel-title-and-description-to-be-announced/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220121T120000
DTEND;TZID=America/New_York:20220121T130000
DTSTAMP:20260422T233526
CREATED:20210719T222003Z
LAST-MODIFIED:20220110T192356Z
UID:10000524-1642766400-1642770000@www.med.unc.edu
SUMMARY:TARC Research Seminar: Dr. Chris Kepley; "Wandering in the sciences; from nanotechnology\, to sustainable oceans\, to a new cancer immunotherapy"
DESCRIPTION:“Wandering in the sciences; from nanotechnology\, to sustainable oceans\, to a new cancer immunotherapy” \nChris Kepley\, PhD \nAssociate Professor\, Nanoscience \nUniversity of NC\, Greensboro \n\n\n\nVirtual (Zoom) \nURL: https://zoom.us/j/92101985767?pwd=d3hHbWhHMFlQSm05RmdCVVVmMkVIUT09 \nMeeting ID: 921 0198 5767 \nPasscode: 005755 \nPhone (New York): 929-205-6099 \nPhone (Toll-free): 888-475-4499
URL:https://www.med.unc.edu/tarc/event/tarc-research-seminar-title-and-description-to-be-announced-4/
LOCATION:Remote or In Person Options Available
CATEGORIES:TARC Research Seminar
END:VEVENT
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