{"id":15785,"date":"2024-02-08T14:12:22","date_gmt":"2024-02-08T19:12:22","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/?page_id=15785"},"modified":"2025-09-25T13:35:43","modified_gmt":"2025-09-25T17:35:43","slug":"clinical-databases-and-biorepositories","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/","title":{"rendered":"Clinical Databases and Biorepositories"},"content":{"rendered":"

TARC Clinical Databases and Biorepositories<\/h2>\nThis table includes details for current clinical databases and biorepositories associated with TARC investigators. For anyone interested in learning more about the databases and biospecimens available or interested in collaborating on a project that utilizes the below resources, please reach out to the contact person listed for the study of interest. <\/span>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Name of Study<\/th>PI Name(s) & Contact(s)<\/th>Clinical Variables<\/th>Biospecimens<\/th>Collection Timepoints<\/th>Enrolled Individuals<\/th>\n<\/tr>\n<\/thead>\n
Total Knee Arthroplasty Database and Biorepository<\/td>Daniel Bracey, Richard Loeser, Joseph Hart
\n
\nContact: Richard Loeser (Richard_Loeser@med.unc.edu)<\/td>		- Demographics
\n- Medications
\n- Radiographs
\n- Knee ROM
\n- PROMIS-29 (pain, depression, anxiety)
\n- KOOS (pain and function)
\n- PCS (pain)<\/td>		- Joint tissue (cartilage and synovial tissue)
\n
\nPlanned:
\n- Synovial fluid
\n- Blood
\n- Urine<\/td>		Tissue and synovial fluid:
\n- Time of surgery
\n
\nBlood and urine:
\n- Time of surgery
\n- 3mo
\n- Post-surgery
\n
\nRadiographs:
\n- Pre-op
\n- 1, 2 and 5yrs post-surgery
\n
\n<\/td>		Enrollment goal of 500<\/td>\n<\/tr>\n
LCCC 1937-Immuno-Oncology Database: Identifying Mechanisms of Autoimmune Diseases in the Era of Cancer Immunotherapy<\/td>Rumey Ishizawar
\n
\nContact(s): Shruti Saxena Beem (shruti_saxena@med.unc.edu)<\/td>		- General health
\n- Medications
\n- Allergies
\n- Comorbidities
\n- Autoimmune conditions
\n- Demographics
\n- Socioeconomic status
\n- Quality of Life
\n- Cancer diagnosis, treatment, and history
\n- Immune-related adverse events<\/td>		- DNA from cheek swab
\n- Blood serum
\n- PBMCs
\n- Whole urine
\n- Urine supernatant and pellet
\n- Feces for microbiome<\/td>		- Baseline
\n- Every 12wks until 2yrs after ICI therapy<\/td>		Enrollment goal of 200
\n
\n- 24 currently enrolled<\/td>\n<\/tr>\n
Alpha-gal Allergy<\/td>Scott Commins
\n
\nContact: Scott Commins (scommins@email.unc.edu)<\/td>		- Allergic or not allergic<\/td>- Plasma
\n- Sera
\n- PBMCs<\/td>		2020-2023<\/td>Approx. 400 enrolled<\/td>\n<\/tr>\n
Identification of Causes and Markers of Renal Disease<\/td>Ronald Falk
\n
\nContact: Lauren Blazek (lmccabe@email.unc.edu)<\/td>		- Treatment
\n- Outcomes
\n- Histopathology<\/td>		- Blood
\n- Urine
\n- Stool<\/td>		- Once\/yr from participants with glomerular disease (varies depending on cohort)<\/td>3,000 enrolled<\/td>\n<\/tr>\n
Longitudinal ACL Injury Database<\/td>Brian Pietrosimone
\n
\nContact: Brian Pietrosimone (pietrosi@email.unc.edu)<\/td>		- Biomechanics
\n- Knee joint MRI
\n- Patient reported outcomes (KOOS, IKDC, Kinesiophobia)<\/td>		- Synovial fluid
\n- Serum
\n- Plasma
\n- Urine<\/td>		- Preoperative
\n- Time of ACL reconstruction
\n- 2, 4, 6, and 12mo post-ACL reconstruction<\/td>		60 enrolled<\/td>\n<\/tr>\n
The Johnston County Health Study<\/td>Amanda Nelson
\n
\nContact: Patrick Gale (w.patrick.gale@unc.edu)<\/td>		- General health
\n- Medications
\n- Allergies
\n- Comorbidities
\n- Autoimmune conditions
\n- Demographics
\n- Socioeconomic status
\n- Radiographs
\n- Ultrasounds<\/td>		- Serum
\n- Plasma
\n- Urine
\n- White cells<\/td>		2019 - 2024<\/td>902 enrolled<\/td>\n<\/tr>\n
<\/td><\/td><\/td><\/td><\/td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

This table was updated on 09\/25\/2025.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

This table was updated on 09\/25\/2025.<\/p>\n","protected":false},"author":114753,"featured_media":0,"parent":3227,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-15785","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"\nClinical Databases and Biorepositories | Thurston Arthritis Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical Databases and Biorepositories | Thurston Arthritis Research Center\" \/>\n<meta property=\"og:description\" content=\"This table was updated on 09\/25\/2025.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/\" \/>\n<meta property=\"og:site_name\" content=\"Thurston Arthritis Research Center\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/unctarc\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-25T17:35:43+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@UNCTARC\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/\",\"url\":\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/\",\"name\":\"Clinical Databases and Biorepositories | Thurston Arthritis Research Center\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/#website\"},\"datePublished\":\"2024-02-08T19:12:22+00:00\",\"dateModified\":\"2025-09-25T17:35:43+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/tarc\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\",\"item\":\"https:\/\/www.med.unc.edu\/tarc\/research\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Clinical Databases and Biorepositories\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/tarc\/\",\"name\":\"Thurston Arthritis Research Center\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/tarc\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Clinical Databases and Biorepositories | Thurston Arthritis Research Center","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/","og_locale":"en_US","og_type":"article","og_title":"Clinical Databases and Biorepositories | Thurston Arthritis Research Center","og_description":"This table was updated on 09\/25\/2025.","og_url":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/","og_site_name":"Thurston Arthritis Research Center","article_publisher":"https:\/\/www.facebook.com\/unctarc","article_modified_time":"2025-09-25T17:35:43+00:00","twitter_card":"summary_large_image","twitter_site":"@UNCTARC","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/","url":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/","name":"Clinical Databases and Biorepositories | Thurston Arthritis Research Center","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/tarc\/#website"},"datePublished":"2024-02-08T19:12:22+00:00","dateModified":"2025-09-25T17:35:43+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/tarc\/research\/clinical-databases-and-biorepositories\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/tarc\/"},{"@type":"ListItem","position":2,"name":"Research","item":"https:\/\/www.med.unc.edu\/tarc\/research\/"},{"@type":"ListItem","position":3,"name":"Clinical Databases and Biorepositories"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/tarc\/#website","url":"https:\/\/www.med.unc.edu\/tarc\/","name":"Thurston Arthritis Research Center","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/tarc\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/pages\/15785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/users\/114753"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/comments?post=15785"}],"version-history":[{"count":1,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/pages\/15785\/revisions"}],"predecessor-version":[{"id":16893,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/pages\/15785\/revisions\/16893"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/pages\/3227"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/media?parent=15785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}