{"id":10846,"date":"2021-02-10T11:55:54","date_gmt":"2021-02-10T16:55:54","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/?p=10846"},"modified":"2021-02-11T14:19:32","modified_gmt":"2021-02-11T19:19:32","slug":"dr-richard-loeser-co-authors-jama-review-article-on-diagnosis-and-treatment-of-hip-and-knee-osteoarthritis","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/tarc\/dr-richard-loeser-co-authors-jama-review-article-on-diagnosis-and-treatment-of-hip-and-knee-osteoarthritis\/","title":{"rendered":"Dr. Richard Loeser Co-Authors Comprehensive JAMA Review Article, Providing Key Insights Into the Causes, Diagnosis &amp; Treatment of Hip and Knee Osteoarthritis"},"content":{"rendered":"<p><a href=\"https:\/\/www.med.unc.edu\/tarc\/wp-content\/uploads\/sites\/802\/2020\/08\/Dr-Richard-Loeser-smsq-1-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-thumbnail wp-image-9848\" src=\"https:\/\/www.med.unc.edu\/tarc\/wp-content\/uploads\/sites\/802\/2020\/08\/Dr-Richard-Loeser-smsq-1-150x150.jpg\" alt=\"Dr. Richard Loeser\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.med.unc.edu\/tarc\/wp-content\/uploads\/sites\/802\/2020\/08\/Dr-Richard-Loeser-smsq-1-150x150.jpg 150w, https:\/\/www.med.unc.edu\/tarc\/wp-content\/uploads\/sites\/802\/2020\/08\/Dr-Richard-Loeser-smsq-1-600x600.jpg 600w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a>The article provides a review of previous, current and evolving views regarding the disease, including treatments ranging from behavior modification, to advanced new therapies.<\/p>\n<p>Long characterized as a wear-and-tear disorder, osteoarthritis (OA) is now understood to have a complex pathophysiology affecting multiple joints and joint structures.\u00a0 As described by the Osteoarthritis Research Society International definition: \u201cThe disease manifests first as a molecular derangement (abnormal joint tissue metabolism) followed by anatomic, and\/or physiologic derangements (characterized by cartilage degradation, bone remodeling, osteophyte formation, joint inflammation and loss.&#8221;<\/p>\n<p>The published paper also reviews the guidelines of various professional organizations regarding recommended\/not-recommended treatment options for osteoarthritis of the hip and knee.<\/p>\n<p>To access the abstract and article through the JAMA website,<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/article-abstract\/2776205\">\u00a0use this link.<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The article provides a review of previous, current and evolving views regarding the disease, including treatments ranging from behavior modification, to advanced new therapies.<\/p>\n","protected":false},"author":58060,"featured_media":9847,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-10846","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Richard Loeser Co-Authors Comprehensive JAMA Review Article, Providing Key Insights Into the Causes, Diagnosis &amp; 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